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The Fine LINE: Methylation Drawing the Cancer Landscape
LINE-1 (L1) is the most abundant mammalian transposable element that comprises nearly 20% of the genome, and nearly half of the mammalian genome has stemmed from L1-mediated mobilization. Expression and retrotransposition of L1 are suppressed by complex mechanisms, where the key role belongs to DNA...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi Limited
2015-01-01
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| Collection: | BioMed Research International |
| Accès en ligne: | http://dx.doi.org/10.1155/2015/131547 |
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