The biological significance of brain barrier mechanisms: help or hindrance in drug delivery to the central nervous system? [version 1; referees: 2 approved]

Barrier mechanisms in the brain are important for its normal functioning and development. Stability of the brain’s internal environment, particularly with respect to its ionic composition, is a prerequisite for the fundamental basis of its function, namely transmission of nerve impulses. In addition...

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Main Authors: Norman R. Saunders, Mark D. Habgood, Kjeld Møllgård, Katarzyna M. Dziegielewska
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Ltd 2016-03-01
Serier:F1000Research
Fag:
Neurobiology of Disease & Regeneration
Neurodevelopment
Neuronal & Glial Cell Biology
Neuropharmacology & Psychopharmacology
Pharmacokinetics & Drug Delivery
Online adgang:http://f1000research.com/articles/5-313/v1
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