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let-7 miRNAs Can Act through Notch to Regulate Human Gliogenesis

It is clear that neural differentiation from human pluripotent stem cells generates cells that are developmentally immature. Here, we show that the let-7 plays a functional role in the developmental decision making of human neural progenitors, controlling whether these cells make neurons or glia. Th...

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Main Authors: M. Patterson, X. Gaeta, K. Loo, M. Edwards, S. Smale, J. Cinkornpumin, Y. Xie, J. Listgarten, S. Azghadi, S.M. Douglass, M. Pellegrini, W.E. Lowry
格式: Artigo
語言:Inglês
出版: Elsevier 2014-11-01
叢編:Stem Cell Reports
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2213671114002690
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