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let-7 miRNAs Can Act through Notch to Regulate Human Gliogenesis
It is clear that neural differentiation from human pluripotent stem cells generates cells that are developmentally immature. Here, we show that the let-7 plays a functional role in the developmental decision making of human neural progenitors, controlling whether these cells make neurons or glia. Th...
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Main Authors: | , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Elsevier
2014-11-01
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叢編: | Stem Cell Reports |
在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2213671114002690 |
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