let-7 miRNAs Can Act through Notch to Regulate Human Gliogenesis

It is clear that neural differentiation from human pluripotent stem cells generates cells that are developmentally immature. Here, we show that the let-7 plays a functional role in the developmental decision making of human neural progenitors, controlling whether these cells make neurons or glia. Th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: M. Patterson, X. Gaeta, K. Loo, M. Edwards, S. Smale, J. Cinkornpumin, Y. Xie, J. Listgarten, S. Azghadi, S.M. Douglass, M. Pellegrini, W.E. Lowry
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014-11-01
Schriftenreihe:Stem Cell Reports
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2213671114002690
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge