Prevention against diffuse spinal cord astrocytoma: can the Notch pathway be a novel treatment target?

This study was designed to investigate whether the Notch pathway is involved in the development of diffuse spinal cord astrocytomas. BALB/c nude mice received injections of CD133 + and CD133− cell suspensions prepared using human recurrent diffuse spinal cord astrocytoma tissue through administratio...

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Huvudupphovsmän: Jian-jun Sun, Zhen-yu Wang, Ling-song Li, Hai-yan Yu, Yong-sheng Xu, Hai-bo Wu, Yi Luo, Bin Liu, Mei Zheng, Jin-long Mao, Xiao-hui Lou
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wolters Kluwer Medknow Publications 2015-01-01
Serie:Neural Regeneration Research
Ämnen:
Alzheimer′s disease
amyloid-β
astrocytes
Ca 2+
calcilytic
calcium-sensing receptor
nitromemantine
NPS 2143
α7-nicotinic acetylcholine receptor
nerve regeneration
spinal cord injury
surgical decompression
tumor necrosis factor α
cell apoptosis
neurological function
neural regeneration
contusion
Nogo-A
axon growth
immunohistochemistry
fluorescent quantitative PCR
Schwann cells
cell transplantation
edaravone
motor function
electrophysiological function
electroacupuncture
intervertebral disc
blood circulation
inflammation
neuroprotection
neurons
NSFC grants
astrocytoma
mice
immunodeficiency (BALB/c) mice
Notch
nestin
glial fibrillary acidic protein
CD133
spinal cord
brain
MRI
Länkar:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=2;spage=244;epage=251;aulast=Sun
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