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RocA truncation underpins hyper-encapsulation, carriage longevity and transmissibility of serotype M18 group A streptococci.

Group A streptococcal isolates of serotype M18 are historically associated with epidemic waves of pharyngitis and the non-suppurative immune sequela rheumatic fever. The serotype is defined by a unique, highly encapsulated phenotype, yet the molecular basis for this unusual colony morphology is unkn...

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Auteurs principaux: Nicola N Lynskey, David Goulding, Magdalena Gierula, Claire E Turner, Gordon Dougan, Robert J Edwards, Shiranee Sriskandan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2013-01-01
Collection:PLoS Pathogens
Accès en ligne:https://doi.org/10.1371/journal.ppat.1003842
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