16S rDNA ?-? interactions Bacillus Bayesian optimization Hg isotopes M. polymorpha acid mine drainage adsorption kinetics adsorption mechanisms adsorption removal algae cells ammonia nitrogen antibiotic resistance genes (ARGs) antibiotic resistant bacteria (ARB) antibiotics aquaculture aquaculture wastewater benzene and toluene bioavailability biochar biological aerated filters biomineralization bioremediation biosorption biotransformation chromium contamination copper slag copper smelter cow manure