Comparing platforms for C. elegans mutant identification using high-throughput whole-genome sequencing.

por Yufeng Shen, Sumeet Sarin, Ye Liu, Oliver Hobert, Itsik Pe'er
Publicado 2008-01-01

ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs.

por Paola Nicoletti, Mukesh Bansal, Celine Lefebvre, Paolo Guarnieri, Yufeng Shen, Itsik Pe'er, Andrea Califano, Aris Floratos
Publicado 2015-01-01

Congenital diaphragmatic hernias: from genes to mechanisms to therapies

por Gabrielle Kardon, Kate G. Ackerman, David J. McCulley, Yufeng Shen, Julia Wynn, Linshan Shang, Eric Bogenschutz, Xin Sun, Wendy K. Chung
Publicado 2017-08-01

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

por Brahma V. Kumar, Wenji Ma, Michelle Miron, Tomer Granot, Rebecca S. Guyer, Dustin J. Carpenter, Takashi Senda, Xiaoyun Sun, Siu-Hong Ho, Harvey Lerner, Amy L. Friedman, Yufeng Shen, Donna L. Farber
Publicado 2017-09-01

Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas

por Guojie Zhong, Priyanka Ahimaz, Nicole A. Edwards, Jacob J. Hagen, Christophe Faure, Qiao Lu, Paul Kingma, William Middlesworth, Julie Khlevner, Mahmoud El Fiky, David Schindel, Elizabeth Fialkowski, Adhish Kashyap, Sophia Forlenza, Alan P. Kenny, Aaron M. Zorn, Yufeng Shen, Wendy K. Chung
Publicado 2022-07-01

Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease

por Na Zhu, Carrie L. Welch, Jiayao Wang, Philip M. Allen, Claudia Gonzaga-Jauregui, Lijiang Ma, Alejandra K. King, Usha Krishnan, Erika B. Rosenzweig, D. Dunbar Ivy, Eric D. Austin, Rizwan Hamid, Michael W. Pauciulo, Katie A. Lutz, William C. Nichols, Jeffrey G. Reid, John D. Overton, Aris Baras, Frederick E. Dewey, Yufeng Shen, Wendy K. Chung
Publicado 2018-07-01

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

por Alexander Hsieh, Sarah U. Morton, Jon A. L. Willcox, Joshua M. Gorham, Angela C. Tai, Hongjian Qi, Steven DePalma, David McKean, Emily Griffin, Kathryn B. Manheimer, Daniel Bernstein, Richard W. Kim, Jane W. Newburger, George A. Porter, Deepak Srivastava, Martin Tristani-Firouzi, Martina Brueckner, Richard P. Lifton, Elizabeth Goldmuntz, Bruce D. Gelb, Wendy K. Chung, Christine E. Seidman, J. G. Seidman, Yufeng Shen
Publicado 2020-04-01