Hakutulokset - Wim Robberecht

Modelling amyotrophic lateral sclerosis: progress and possibilities Tekijä Philip Van Damme, Wim Robberecht, Ludo Van Den Bosch

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Ivermectin inhibits AMPA receptor-mediated excitotoxicity in cultured motor neurons and extends the life span of a transgenic mouse model of amyotrophic lateral sclerosis Tekijä Maria Andries, Philip Van Damme, Wim Robberecht, Ludo Van Den Bosch

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Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1G93A-induced motor neuron death Tekijä Maarten Dewil, Vidal F. dela Cruz, Ludo Van Den Bosch, Wim Robberecht

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Skeletal muscle properties in a transgenic mouse model for amyotrophic lateral sclerosis: effects of creatine treatment Tekijä Wim Derave, Ludo Van Den Bosch, Griet Lemmens, Bert O Eijnde, Wim Robberecht, Peter Hespel

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Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration Tekijä Ludo Van Den Bosch, Erik Storkebaum, Vicky Vleminckx, Lieve Moons, Ludo Vanopdenbosch, Wendy Scheveneels, Peter Carmeliet, Wim Robberecht

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Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy. Tekijä Angela S Laird, Annelies Van Hoecke, Louis De Muynck, Mieke Timmers, Ludo Van den Bosch, Philip Van Damme, Wim Robberecht

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Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice Tekijä Sander Beel, Sarah Herdewyn, Raheem Fazal, Mathias De Decker, Matthieu Moisse, Wim Robberecht, Ludo Van Den Bosch, Philip Van Damme

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Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis Tekijä Annelies Nonneman, Nathan Criem, Sebastian A. Lewandowski, Rik Nuyts, Dietmar R. Thal, Frank W. Pfrieger, John Ravits, Philip Van Damme, An Zwijsen, Ludo Van Den Bosch, Wim Robberecht

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Lowering EphA4 Does Not Ameliorate Disease in a Mouse Model for Severe Spinal Muscular Atrophy Tekijä Lindsay Poppe, Lindsay Poppe, Silke Smolders, Silke Smolders, Laura Rué, Laura Rué, Mieke Timmers, Mieke Timmers, Annette Lenaerts, Annette Lenaerts, Annet Storm, Annet Storm, Lies Schoonaert, Lies Schoonaert, Antina de Boer, Antina de Boer, Philip Van Damme, Philip Van Damme, Philip Van Damme, Ludo Van Den Bosch, Ludo Van Den Bosch, Wim Robberecht, Wim Robberecht, Robin Lemmens, Robin Lemmens, Robin Lemmens

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CuZn-Superoxide Dismutase in D90A Heterozygotes from Recessive and Dominant ALS Pedigrees Tekijä P.Andreas Jonsson, Åsa Bäckstrand, Peter M. Andersen, Johan Jacobsson, Matthew Parton, Chris Shaw, Robert Swingler, Pamela J. Shaw, Wim Robberecht, Albert C. Ludolph, Teepu Siddique, Veronica I. Skvortsova, Stefan L. Marklund

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EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer’s disease Tekijä Lindsay Poppe, Laura Rué, Mieke Timmers, Annette Lenaerts, Annet Storm, Zsuzsanna Callaerts-Vegh, Gilles Courtand, Antina de Boer, Silke Smolders, Philip Van Damme, Ludo Van Den Bosch, Rudi D’Hooge, Bart De Strooper, Wim Robberecht, Robin Lemmens

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Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth Tekijä Lawrence Van Helleputte, Mandy Kater, Dana P. Cook, Caroline Eykens, Elisabeth Rossaert, Wanda Haeck, Tom Jaspers, Natasja Geens, Pieter Vanden Berghe, Conny Gysemans, Chantal Mathieu, Wim Robberecht, Philip Van Damme, Guido Cavaletti, Matthew Jarpe, Ludo Van Den Bosch

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Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity Tekijä Elke Bogaert, Steven Boeynaems, Masato Kato, Lin Guo, Thomas R. Caulfield, Jolien Steyaert, Wendy Scheveneels, Nathalie Wilmans, Wanda Haeck, Nicole Hersmus, Joost Schymkowitz, Frederic Rousseau, James Shorter, Patrick Callaerts, Wim Robberecht, Philip Van Damme, Ludo Van Den Bosch

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AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS Tekijä Caroline Eykens, Elisabeth Rossaert, Sandra Duqué, Laura Rué, André Bento-Abreu, Nicole Hersmus, Annette Lenaerts, Axelle Kerstens, Nikky Corthout, Sebastian Munck, Philip Van Damme, Matthew G. Holt, Georg von Jonquires, Matthias Klugmann, Ludo Van Den Bosch, Wim Robberecht

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Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis Tekijä Laura Rué, Patrick Oeckl, Mieke Timmers, Annette Lenaerts, Jasmijn van der Vos, Silke Smolders, Lindsay Poppe, Antina de Boer, Ludo Van Den Bosch, Philip Van Damme, Jochen H. Weishaupt, Albert C. Ludolph, Markus Otto, Wim Robberecht, Robin Lemmens

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Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice Tekijä Kim A. Staats, Lawrence Van Helleputte, Ashley R. Jones, André Bento-Abreu, Annelies Van Hoecke, Aleksey Shatunov, Claire L. Simpson, Robin Lemmens, Tom Jaspers, Kiyoko Fukami, Yoshikazu Nakamura, Robert H. Brown, Jr., Philip Van Damme, Adrian Liston, Wim Robberecht, Ammar Al-Chalabi, Ludo Van Den Bosch

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HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients Tekijä Wenting Guo, Maximilian Naujock, Laura Fumagalli, Tijs Vandoorne, Pieter Baatsen, Ruben Boon, Laura Ordovás, Abdulsamie Patel, Marc Welters, Thomas Vanwelden, Natasja Geens, Tine Tricot, Veronick Benoy, Jolien Steyaert, Cynthia Lefebvre-Omar, Werend Boesmans, Matthew Jarpe, Jared Sterneckert, Florian Wegner, Susanne Petri, Delphine Bohl, Pieter Vanden Berghe, Wim Robberecht, Philip Van Damme, Catherine Verfaillie, Ludo Van Den Bosch

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The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases Tekijä Zhongbo Chen, Regina H. Reynolds, Antonio F. Pardiñas, Sarah A. Gagliano Taliun, Wouter van Rheenen, Kuang Lin, Aleksey Shatunov, Emil K. Gustavsson, Isabella Fogh, Ashley R. Jones, Wim Robberecht, Philippe Corcia, Adriano Chiò, Pamela J. Shaw, Karen E. Morrison, Jan H. Veldink, Leonard H. van den Berg, Christopher E. Shaw, John F. Powell, Vincenzo Silani, John A. Hardy, Henry Houlden, Michael J. Owen, Martin R. Turner, Mina Ryten, Ammar Al-Chalabi

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Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data Tekijä Ahmad Al Khleifat, Alfredo Iacoangeli, Alfredo Iacoangeli, Ashley R. Jones, Joke J. F. A. van Vugt, Matthieu Moisse, Matthieu Moisse, Aleksey Shatunov, Aleksey Shatunov, Ramona A. J. Zwamborn, Rick A. A. van der Spek, Johnathan Cooper-Knock, Simon Topp, Wouter van Rheenen, Brendan Kenna, Kristel R. Van Eijk, Kevin Kenna, Ross Byrne, Victoria López, Sarah Opie-Martin, Atay Vural, Yolanda Campos, Markus Weber, Markus Weber, Bradley Smith, Isabella Fogh, Vincenzo Silani, Vincenzo Silani, Karen E. Morrison, Richard Dobson, Richard Dobson, Michael A. van Es, Russell L. McLaughlin, Patrick Vourc’h, Adriano Chio, Adriano Chio, Philippe Corcia, Philippe Corcia, Mamede de Carvalho, Marc Gotkine, Monica Povedano Panades, Jesus S. Mora, Pamela J. Shaw, John E. Landers, Jonathan D. Glass, Christopher E. Shaw, Christopher E. Shaw, Nazli Basak, Orla Hardiman, Orla Hardiman, Wim Robberecht, Wim Robberecht, Philip Van Damme, Philip Van Damme, Leonard H. van den Berg, Jan H. Veldink, Ammar Al-Chalabi, Ammar Al-Chalabi

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Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. Tekijä Frank P Diekstra, Christiaan G J Saris, Wouter van Rheenen, Lude Franke, Ritsert C Jansen, Michael A van Es, Paul W J van Vught, Hylke M Blauw, Ewout J N Groen, Steve Horvath, Karol Estrada, Fernando Rivadeneira, Albert Hofman, Andre G Uitterlinden, Wim Robberecht, Peter M Andersen, Judith Melki, Vincent Meininger, Orla Hardiman, John E Landers, Robert H Brown, Aleksey Shatunov, Christopher E Shaw, P Nigel Leigh, Ammar Al-Chalabi, Roel A Ophoff, Leonard H van den Berg, Jan H Veldink

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