Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors

par Walker, Scott S., Xu, Yiming, Triantafyllou, Ilias, Waldman, Michelle F., Mendrick, Cara, Brown, Nathaniel, Mann, Paul, Chau, Andrew, Patel, Reena, Bauman, Nicholas, Norris, Christine, Antonacci, Barry, Gurnani, Maya, Cacciapuoti, Anthony, McNicholas, Paul M., Wainhaus, Samuel, Herr, R. Jason, Kuang, Rongze, Aslanian, Robert G., Ting, Pauline C., Black, Todd A.
Publié 2011

Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical mod...

par McLeod, Robbie L., Tulshian, Deen B., Bolser, Donald C., Varty, Geoffrey B., Baptista, Marco, Fernandez, Xiomara, Parra, Leonard E., Zimmer, Jennifer C., Erickson, Christine H., Ho, Ginny D., Jia, Yanlin, Ng, Fay W., Korfmacher, Walter, Xu, Xiaoying, Veals, John, Smith-Torhan, April, Wainhaus, Samuel, Fawzi, Ahmad B., Austin, Theodore M., van Heek, Margaret, Hey, John A.
Publié 2009