Resultados da busca - V.Hugh Perry

The Role of Microglia in Synaptic Stripping and Synaptic Degeneration: A Revised Perspective por V Hugh Perry, Vincent O'Connor

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Brain region specific pre-synaptic and post-synaptic degeneration are early components of neuropathology in prion disease. por Zuzana Šišková, Richard A Reynolds, Vincent O'Connor, V Hugh Perry

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Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration por Karine Palin, Colm Cunningham, Penny Forse, V. Hugh Perry, Nick Platt

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TGFβ1 regulates the inflammatory response during chronic neurodegeneration por Delphine Boche, Colm Cunningham, Fabian Docagne, Helen Scott, V. Hugh Perry

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Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology por Bryony C. Gray, Zuzana Siskova, V. Hugh Perry, Vincent O'Connor

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Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease. por Kathryn J Hilton, Colm Cunningham, Richard A Reynolds, V Hugh Perry

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Soluble axoplasm enriched from injured CNS axons reveals the early modulation of the actin cytoskeleton. por Patrick Garland, Lucy J Broom, Shmma Quraishe, Paul D Dalton, Paul Skipp, Tracey A Newman, V Hugh Perry

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The role of activity in synaptic degeneration in a protein misfolding disease, prion disease. por Matteo Caleo, Laura Restani, Eleonora Vannini, Zuzana Siskova, Hussain Al-Malki, Ruth Morgan, Vincent O'Connor, V Hugh Perry

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Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration. por James Alibhai, Richard A Blanco, Marcelo A Barria, Pedro Piccardo, Byron Caughey, V Hugh Perry, Tom C Freeman, Jean C Manson

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Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer’s disease por Sarmi Sri, Chrysia-Maria Pegasiou, Chantal Abbigail Cave, Katie Hough, Natalie Wood, Diego Gomez-Nicola, Katrin Deinhardt, David Bannerman, V. Hugh Perry, Mariana Vargas-Caballero

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MRI and MRS alterations in the preclinical phase of murine prion disease: Association with neuropathological and behavioural changes por Kerry A. Broom, Daniel C. Anthony, John P. Lowe, Julian L. Griffin, Helen Scott, Andrew M. Blamire, Peter Styles, V. Hugh Perry, Nicola R. Sibson

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease por Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, NIMA Consortium, Diego Gómez-Nicola, V. Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A. Parker, Diana Cash

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An Inducible Mouse Model of Late Onset Tay–Sachs Disease por Mylvaganam Jeyakumar, David Smith, Elena Eliott-Smith, Mario Cortina-Borja, Gabriele Reinkensmeier, Terry D. Butters, Thorsten Lemm, Konrad Sandhoff, V.Hugh Perry, Raymond A. Dwek, Frances M. Platt

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Periodontitis and Cognitive Decline in Alzheimer's Disease. por Mark Ide, Marina Harris, Annette Stevens, Rebecca Sussams, Viv Hopkins, David Culliford, James Fuller, Paul Ibbett, Rachel Raybould, Rhodri Thomas, Ursula Puenter, Jessica Teeling, V Hugh Perry, Clive Holmes

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Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain por Katharine Askew, Kaizhen Li, Adrian Olmos-Alonso, Fernando Garcia-Moreno, Yajie Liang, Philippa Richardson, Tom Tipton, Mark A. Chapman, Kristoffer Riecken, Sol Beccari, Amanda Sierra, Zoltán Molnár, Mark S. Cragg, Olga Garaschuk, V. Hugh Perry, Diego Gomez-Nicola

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Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration por Juliane Obst, Emilie Simon, Maria Martin-Estebane, Elena Pipi, Liana M. Barkwill, Ivette Gonzalez-Rivera, Fergus Buchanan, Alan R. Prescott, Dorte Faust, Simon Fox, Janet Brownlees, Debra Taylor, V. Hugh Perry, Hugh Nuthall, Peter J. Atkinson, Eric Karran, Carol Routledge, Diego Gomez-Nicola

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