Søgeresultater - Timothy A Springer

Low-affinity integrin states have faster ligand-binding kinetics than the high-affinity state af Jing Li, Jiabin Yan, Timothy A Springer

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Coordinated integrin activation by actin-dependent force during T-cell migration af Pontus Nordenfelt, Hunter L. Elliott, Timothy A. Springer

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A specific interface between integrin transmembrane helices and affinity for ligand. af Bing-Hao Luo, Timothy A Springer, Junichi Takagi

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Monomeric prefusion structure of an extremophile gamete fusogen and stepwise formation of the postfusion trimeric state af Juan Feng, Xianchi Dong, Yang Su, Chafen Lu, Timothy A. Springer

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Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy af Travis I. Moore, Jesse Aaron, Teng-Leong Chew, Timothy A. Springer

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General structural features that regulate integrin affinity revealed by atypical αVβ8 af Jianchuan Wang, Yang Su, Roxana E. Iacob, John R. Engen, Timothy A. Springer

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Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia af Loredana Bury, Emanuela Falcinelli, Davide Chiasserini, Timothy A. Springer, Joseph E. Italiano, Paolo Gresele

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Flow-induced elongation of von Willebrand factor precedes tension-dependent activation af Hongxia Fu, Yan Jiang, Darren Yang, Friedrich Scheiflinger, Wesley P. Wong, Timothy A. Springer

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Structural insights into MIC2 recognition by MIC2-associated protein in Toxoplasma gondii af Su Zhang, Fangfang Wang, Dujuan Zhang, Dongsheng Liu, Wei Ding, Timothy A. Springer, Gaojie Song

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Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker af Klaus Bonazza, Roxana E Iacob, Nathan E Hudson, Jing Li, Chafen Lu, John R Engen, Timothy A Springer

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Design and assessment of TRAP-CSP fusion antigens as effective malaria vaccines. af Chafen Lu, Gaojie Song, Kristin Beale, Jiabin Yan, Emma Garst, Juan Feng, Emily Lund, Flaminia Catteruccia, Timothy A Springer

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Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP af Dennis Klug, Sarah Goellner, Jessica Kehrer, Julia Sattler, Léanne Strauss, Mirko Singer, Chafen Lu, Timothy A Springer, Friedrich Frischknecht

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Single-molecule characterization of subtype-specific β1 integrin mechanics af Myung Hyun Jo, Jing Li, Valentin Jaumouillé, Yuxin Hao, Jessica Coppola, Jiabin Yan, Clare M. Waterman, Timothy A. Springer, Taekjip Ha

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Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2 af Juan Feng, Xianchi Dong, Adam DeCosta, Yang Su, Fiona Angrisano, Katarzyna A Sala, Andrew M Blagborough, Chafen Lu, Timothy A Springer

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Fusion surface structure, function, and dynamics of gamete fusogen HAP2 af Juan Feng, Xianchi Dong, Jennifer Pinello, Jun Zhang, Chafen Lu, Roxana E Iacob, John R Engen, William J Snell, Timothy A Springer

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Complex structure of engineered modular domains defining molecular interaction between ICAM-1 and integrin LFA-1. af Sungkwon Kang, Chae Un Kim, Xiaoling Gu, Roisin M Owens, Sarah J van Rijn, Vanissra Boonyaleepun, Yuxin Mao, Timothy A Springer, Moonsoo M Jin

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Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits af Yuxin Hao, Jiabin Yan, Courtney Fraser, Aiping Jiang, Murali Anuganti, Roushu Zhang, Kenneth Lloyd, Joseph Jardine, Jessica Coppola, Rob Meijers, Jing Li, Timothy A. Springer

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Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse [version 2; referees: 2 approved] af Chiara Beilin, Kaushik Choudhuri, Gerben Bouma, Dessislava Malinova, Jaime Llodra, David L. Stokes, Motumu Shimaoka, Timothy A. Springer, Michael L. Dustin, Adrian J. Thrasher, Siobhan O. Burns

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Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics... af Kristian E Swearingen, Scott E Lindner, Lirong Shi, Melanie J Shears, Anke Harupa, Christine S Hopp, Ashley M Vaughan, Timothy A Springer, Robert L Moritz, Stefan H I Kappe, Photini Sinnis

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Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus af Abhay Kotecha, Quan Wang, Xianchi Dong, Serban L. Ilca, Marina Ondiviela, Rao Zihe, Julian Seago, Bryan Charleston, Elizabeth E. Fry, Nicola G. A. Abrescia, Timothy A. Springer, Juha T. Huiskonen, David I. Stuart

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