Bilaketaren emaitzak - Thorsten Stiewe

p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein folding nork Oleg Timofeev, Thorsten Stiewe

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Fragility of precision: resistance to mutant p53 reactivation nork Andreas C. Joerger, Thorsten Stiewe

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Robustness of the Autophagy Pathway to Somatic Copy Number Losses nork Pierfrancesco Polo, Niklas Gremke, Thorsten Stiewe, Michael Wanzel

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MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6. nork Bastian Stielow, Florian Finkernagel, Thorsten Stiewe, Andrea Nist, Guntram Suske

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Phosphoproteomics Reveals Selective Regulation of Signaling Pathways by Lysophosphatidic Acid Species in Macrophages nork Raimund Dietze, Witold Szymanski, Kaire Ojasalu, Florian Finkernagel, Andrea Nist, Thorsten Stiewe, Johannes Graumann, Rolf Müller

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Low-penetrance TP53 variants are mainly hypomorphic: an underestimated issue with high clinical significance nork Lea Rodriguez, Bernard Leroy, Franck Toledo, Julianne Susanne Funk, Thorsten Stiewe, Panagiotis Baliakas, François Delhommeau, Thierry Soussi

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The Nuclear Proteins TP73 and CUL4A Confer Resistance to Cytarabine by Induction of Translesion DNA Synthesis via Mono-ubiquitination of PCNA nork Miriam Rehberger, Jonas A. Schäfer, Anna-Maria Krampitz, Anne Catherine Bretz, Lukas Jost, Torsten Haferlach, Thorsten Stiewe, Andreas Neubauer

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p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo nork Oleg Timofeev, Katharina Schlereth, Michael Wanzel, Attila Braun, Bernhard Nieswandt, Axel Pagenstecher, Andreas Rosenwald, Hans-Peter Elsässer, Thorsten Stiewe

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The CpG Island-Binding Protein SAMD1 Contributes to an Unfavorable Gene Signature in HepG2 Hepatocellular Carcinoma Cells nork Clara Simon, Bastian Stielow, Andrea Nist, Iris Rohner, Lisa Marie Weber, Merle Geller, Sabrina Fischer, Thorsten Stiewe, Robert Liefke

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Mutant p53-ENTPD5 control of the calnexin/calreticulin cycle: a druggable target for inhibiting integrin-α5-driven metastasis nork Evangelos Pavlakis, Michelle Neumann, Nastasja Merle, Ronja Wieboldt, Michael Wanzel, Viviane Ponath, Elke Pogge von Strandmann, Sabrina Elmshäuser, Thorsten Stiewe

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Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt nork Danai Mavridi, Julianne S. Funk, Dimitrios-Ilias Balourdas, Andreas Krämer, Raysa Khan Tareque, Oleg Timofeev, John Spencer, Thorsten Stiewe, Andreas C. Joerger

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Detection of minimal residual disease in circulating cell-free DNA in acute myeloid leukemia nork Charlotte Sommer, Hildegard I. D. Mack, Madeleine C. Killer, Petra Ross, Andrea Nist, Thorsten Stiewe, Andreas Neubauer, Cornelia Brendel, Elisabeth K. M. Mack

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Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species nork Mohamad K. Hammoud, Celina Meena, Raimund Dietze, Nathalie Hoffmann, Witold Szymanski, Florian Finkernagel, Andrea Nist, Thorsten Stiewe, Johannes Graumann, Elke Pogge von Strandmann, Rolf Müller

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Divergent CD45+ immune landscapes shape the lung tumor microenvironment nork Selma Dizdarević, Selma Dizdarević, René Wiegandt, Andreas Weigert, Andreas Weigert, Thorsten Stiewe, Thorsten Stiewe, Bastian Eul, Stefan Guenther, Friedrich Grimminger, Friedrich Grimminger, Werner Seeger, Werner Seeger, Werner Seeger, Soni Savai Pullamsetti, Soni Savai Pullamsetti, Soni Savai Pullamsetti, Soni Savai Pullamsetti, Mario Looso, Kati Turkowski, Kati Turkowski, Rajkumar Savai, Rajkumar Savai, Rajkumar Savai, Rajkumar Savai

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Side-Directed Release of Differential Extracellular Vesicle-associated microRNA Profiles from Bronchial Epithelial Cells of Healthy and Asthmatic Subjects nork Viktoria E. M. Schindler, Fahd Alhamdan, Christian Preußer, Lukas Hintz, Bilal Alashkar Alhamwe, Andrea Nist, Thorsten Stiewe, Elke Pogge von Strandmann, Daniel P. Potaczek, Clemens Thölken, Holger Garn

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Author Correction: Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses nork Oleg Timofeev, Boris Klimovich, Jean Schneikert, Michael Wanzel, Evangelos Pavlakis, Julia Noll, Samet Mutlu, Sabrina Elmshäuser, Andrea Nist, Marco Mernberger, Boris Lamp, Ulrich Wenig, Alexander Brobeil, Stefan Gattenlöhner, Kernt Köhler, Thorsten Stiewe

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mTOR-driven autophagy suppression defines metabolic vulnerability in CDK4/6 inhibitor-resistant HR+/HER2− breast cancer nork Luise von Wichert, Alina Stroh, Marie Witt, Michael Wanzel, Marco Mernberger, Sebastian Griewing, Thomas Wündisch, Berit M. Pfitzner, Julia Teply-Szymanski, Anne-Sophie Litmeyer, Carsten Denkert, Uwe Wagner, Thorsten Stiewe, Niklas Gremke

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Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling nork Suresh Sivakumar, Sonja Lieber, Raimund Dietze, Vanessa M. Beutgen, Eileen C. Sutor, Sophie Heidemann, Florian Finkernagel, Julia Teply-Szymanski, Andrea Nist, Thorsten Stiewe, Katrin Roth, Silke Reinartz, Johannes Graumann, Sabine Müller-Brüsselbach, Rolf Müller

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Transcriptomic response of prostate cancer cells to carbon ion and photon irradiation with focus on androgen receptor and TP53 signaling nork Jörg Hänze, Lilly M. Mengen, Marco Mernberger, Dinesh Kumar Tiwari, Thomas Plagge, Andrea Nist, Florentine S. B. Subtil, Ulrike Theiss, Fabian Eberle, Katrin Roth, Matthias Lauth, Rainer Hofmann, Rita Engenhart-Cabillic, Thorsten Stiewe, Axel Hegele

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SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma. nork Clara Simon, Inka D Brunke, Bastian Stielow, Ignasi Forné, Anna Mary Steitz, Merle Geller, Iris Rohner, Lisa Marie Weber, Sabrina Fischer, Lea Marie Jeude, Theresa Huber, Andrea Nist, Thorsten Stiewe, Magdalena Huber, Malte Buchholz, Robert Liefke

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