Resultados da pesquisa - Taha Merghoub

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer Por Said Dermime, Said Dermime, Said Dermime, Maysaloun Merhi, Maysaloun Merhi, Taha Merghoub, Taha Merghoub, Taha Merghoub, Taha Merghoub

Obter o texto integral

Targeted APC Activation in Cancer Immunotherapy to Enhance the Abscopal Effect Por Nathan Suek, Luis Felipe Campesato, Taha Merghoub, Taha Merghoub, Danny N. Khalil, Danny N. Khalil

Obter o texto integral

35336 Effect of Nuclear Soluble Adenylyl Cyclase (sAC) on Melanoma Treatment Response Por Jakyung Bang, Marek M. Drozdz, Lauren Dong, Taha Merghoub, Jonathan H. Zippin

Obter o texto integral

604 Combining a novel dual RAF/MEK inhibitor with immunomodulation to promote an anti-tumor response Por Taha Merghoub, Sadna Budhu, Isabell Schulze, Lauren Dong, Hyejin Choi, Nezar Mehanna, Neal Rosen

525 Investigating dynamic IDO-Kyn-AhR pathway-induced tumor immunosuppression using imaging modality to optimize AhR therapeutic intervention Por Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Inna Serganova, Jonathan F Khan, Mamadou A Bah

Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant Por Ning Yang, Aitor Garcia, Cindy Meyer, Thomas Tuschl, Taha Merghoub, Jedd D. Wolchok, Liang Deng

Obter o texto integral

Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia Por Yi Wang, Taha Merghoub, Peihong Dai, Weiyi Wang, Ning Yang, Liang Deng, Shuaitong Liu, Rachel A Giese

Obter o texto integral

493 Tired and hungry: a potential role for CD47 in T cell exhaustion Por Taha Merghoub, Roberta Zappasodi, Cailian Liu, Jedd Wolchok, Levi Mangarin, Pamela Holland, Chien-Huan Weng, David Schroder

968 PD-1hiFoxp3-CD4+ tumor-infiltrating T-cell lineage commitment impacts the immunotherapy outcome Por Jedd D Wolchok, Taha Merghoub, Roberta Zappasodi, Sara Schad, Benjamin Greenbaum, Levi Mark Mangarin, Stephen Martis, Andrea Orlando

619 Pharmacologic modulation of tumor glycolysis to improve responses to immune checkpoint blockade therapy Por Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Levi Mangarin, Svena Verma, Inna Serganova, Rachana Maniyar, Ronald Blasberg, Myat Ko

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity Por Marcela V Maus, Jason Plotkin, Gopinadh Jakka, Guillaume Stewart-Jones, Isabelle Rivière, Taha Merghoub, Jedd Wolchok, Christoph Renner, Michel Sadelain

Obter o texto integral

Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner Por Rikke B. Holmgaard, Dmitriy Zamarin, Yanyun Li, Billel Gasmi, David H. Munn, James P. Allison, Taha Merghoub, Jedd D. Wolchok

Obter o texto integral

Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity Por Dmitriy Zamarin, Rikke B. Holmgaard, Jacob Ricca, Tamar Plitt, Peter Palese, Padmanee Sharma, Taha Merghoub, Jedd D. Wolchok, James P. Allison

Obter o texto integral

696 Single-cell RNA-seq reveals the critical roles of the STING- and MDA5-mediated cytosolic nucleic acid-sensing pathways as well as IFNAR/STAT2 signaling in recombinant MVA-induc... Por Taha Merghoub, Ning Yang, Liang Deng, Tuo Zhang, Shuaitong Liu, Gregory Mazo, Adrian Tan, Jiahu Wang, John Choi, Jenny Zhaoying Xiang

Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model Por Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Liqun Cai, Aliya Holland, Jasmine Thomas, Dina Preise, Alex Somma, Benjamin Gordon, Avigdor Scherz, Jedd D. Wolchok, Jedd D. Wolchok, Jedd D. Wolchok, Joseph Erinjeri, Taha Merghoub, Taha Merghoub, Jonathan A. Coleman, Jonathan A. Coleman

Obter o texto integral

Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity. Por Francesca Avogadri, Taha Merghoub, Maureen F Maughan, Daniel Hirschhorn-Cymerman, John Morris, Erika Ritter, Robert Olmsted, Alan N Houghton, Jedd D Wolchok

Obter o texto integral

789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model Por Alan N Houghton, Jedd D Wolchok, Taha Merghoub, Daniel Hirschhorn, Linda Hamadene, Yacine Marouf, Allison B Warner, Mariam M George, Nicholas J Ceglia

1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade Por Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Svena Verma, Inna Serganova, Lauren Dong, Levi Mark Mangarin, Yacine Marouf, Jonathan F Khan

567 Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of stroma poor cancers Por Taha Merghoub, Sadna Budhu, Luis Felipe Campesato, Aditi Gupta, Catherine Uyttenhove, Aliya Holland, Kelly Fitzgerald, Rachel Giese, Adam Michel, Jacques Van Snick, Gerd Ritter

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway. Por Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng

Obter o texto integral