Résultats de la recherche - Taha Merghoub

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer par Said Dermime, Said Dermime, Said Dermime, Maysaloun Merhi, Maysaloun Merhi, Taha Merghoub, Taha Merghoub, Taha Merghoub, Taha Merghoub

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Targeted APC Activation in Cancer Immunotherapy to Enhance the Abscopal Effect par Nathan Suek, Luis Felipe Campesato, Taha Merghoub, Taha Merghoub, Danny N. Khalil, Danny N. Khalil

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35336 Effect of Nuclear Soluble Adenylyl Cyclase (sAC) on Melanoma Treatment Response par Jakyung Bang, Marek M. Drozdz, Lauren Dong, Taha Merghoub, Jonathan H. Zippin

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604 Combining a novel dual RAF/MEK inhibitor with immunomodulation to promote an anti-tumor response par Taha Merghoub, Sadna Budhu, Isabell Schulze, Lauren Dong, Hyejin Choi, Nezar Mehanna, Neal Rosen

525 Investigating dynamic IDO-Kyn-AhR pathway-induced tumor immunosuppression using imaging modality to optimize AhR therapeutic intervention par Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Inna Serganova, Jonathan F Khan, Mamadou A Bah

Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant par Ning Yang, Aitor Garcia, Cindy Meyer, Thomas Tuschl, Taha Merghoub, Jedd D. Wolchok, Liang Deng

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Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia par Yi Wang, Taha Merghoub, Peihong Dai, Weiyi Wang, Ning Yang, Liang Deng, Shuaitong Liu, Rachel A Giese

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493 Tired and hungry: a potential role for CD47 in T cell exhaustion par Taha Merghoub, Roberta Zappasodi, Cailian Liu, Jedd Wolchok, Levi Mangarin, Pamela Holland, Chien-Huan Weng, David Schroder

968 PD-1hiFoxp3-CD4+ tumor-infiltrating T-cell lineage commitment impacts the immunotherapy outcome par Jedd D Wolchok, Taha Merghoub, Roberta Zappasodi, Sara Schad, Benjamin Greenbaum, Levi Mark Mangarin, Stephen Martis, Andrea Orlando

619 Pharmacologic modulation of tumor glycolysis to improve responses to immune checkpoint blockade therapy par Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Levi Mangarin, Svena Verma, Inna Serganova, Rachana Maniyar, Ronald Blasberg, Myat Ko

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity par Marcela V Maus, Jason Plotkin, Gopinadh Jakka, Guillaume Stewart-Jones, Isabelle Rivière, Taha Merghoub, Jedd Wolchok, Christoph Renner, Michel Sadelain

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Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner par Rikke B. Holmgaard, Dmitriy Zamarin, Yanyun Li, Billel Gasmi, David H. Munn, James P. Allison, Taha Merghoub, Jedd D. Wolchok

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Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity par Dmitriy Zamarin, Rikke B. Holmgaard, Jacob Ricca, Tamar Plitt, Peter Palese, Padmanee Sharma, Taha Merghoub, Jedd D. Wolchok, James P. Allison

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696 Single-cell RNA-seq reveals the critical roles of the STING- and MDA5-mediated cytosolic nucleic acid-sensing pathways as well as IFNAR/STAT2 signaling in recombinant MVA-induc... par Taha Merghoub, Ning Yang, Liang Deng, Tuo Zhang, Shuaitong Liu, Gregory Mazo, Adrian Tan, Jiahu Wang, John Choi, Jenny Zhaoying Xiang

Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model par Sadna Budhu, Kwanghee Kim, Wesley Yip, Stephen La Rosa, Sylvia Jebiwott, Liqun Cai, Aliya Holland, Jasmine Thomas, Dina Preise, Alex Somma, Benjamin Gordon, Avigdor Scherz, Jedd D. Wolchok, Jedd D. Wolchok, Jedd D. Wolchok, Joseph Erinjeri, Taha Merghoub, Taha Merghoub, Jonathan A. Coleman, Jonathan A. Coleman

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Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity. par Francesca Avogadri, Taha Merghoub, Maureen F Maughan, Daniel Hirschhorn-Cymerman, John Morris, Erika Ritter, Robert Olmsted, Alan N Houghton, Jedd D Wolchok

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789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model par Alan N Houghton, Jedd D Wolchok, Taha Merghoub, Daniel Hirschhorn, Linda Hamadene, Yacine Marouf, Allison B Warner, Mariam M George, Nicholas J Ceglia

1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade par Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Svena Verma, Inna Serganova, Lauren Dong, Levi Mark Mangarin, Yacine Marouf, Jonathan F Khan

567 Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of stroma poor cancers par Taha Merghoub, Sadna Budhu, Luis Felipe Campesato, Aditi Gupta, Catherine Uyttenhove, Aliya Holland, Kelly Fitzgerald, Rachel Giese, Adam Michel, Jacques Van Snick, Gerd Ritter

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway. par Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng

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