Risultati della ricerca - Steven M Rowe

An ex vivo rat trachea model reveals abnormal airway physiology and a gland secretion defect in cystic fibrosis. di Elex Harris, Molly Easter, Janna Ren, Stefanie Krick, Jarrod Barnes, Steven M Rowe

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Pulmonary artery enlargement is associated with pulmonary hypertension and decreased survival in severe cystic fibrosis: A cohort study. di Aline N Zouk, Swati Gulati, Dongqi Xing, Keith M Wille, Steven M Rowe, J Michael Wells

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Fibroblast Growth Factor Receptor 4 Deficiency Mediates Airway Inflammation in the Adult Healthy Lung? di Molly Easter, Jaleesa Garth, Elex S. Harris, Elex S. Harris, Ren-Jay Shei, Eric S. Helton, Yuhua Wei, Rebecca Denson, Rennan Zaharias, Steven M. Rowe, Steven M. Rowe, Patrick Geraghty, Christian Faul, Jarrod W. Barnes, Jarrod W. Barnes, Stefanie Krick, Stefanie Krick

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Aspergillus fumigatus is influenced by mucus accumulation, airway inflammation and cystic fibrosis transmembrane conductance regulator function di T. Spencer Poore, Anh Nguyen, Levi Schaefers, Anna Solomonik, Ashleigh Rieglers, Sixto M. Leal, Steven M. Rowe, Susan Birket

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Protective and antifungal properties of Nanodisk-Amphotericin B over commercially available Amphotericin B di Do-Yeon Cho, Kyle J. Hoffman, Gobind S. Gill, Dong-Jin Lim, Daniel Skinner, Calvin Mackey, Steven M. Rowe, Bradford A. Woodworth

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Longitudinal improvements in clinical and functional outcomes following initiation of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis di Kadambari Vijaykumar, Hui Min Leung, Amilcar Barrios, Justin Wade, Heather Y. Hathorne, David P. Nichols, Guillermo J. Tearney, Steven M. Rowe, George M. Solomon

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Reduced sialylation of airway mucin impairs mucus transport by altering the biophysical properties of mucin di Elex S. Harris, Hannah J. McIntire, Marina Mazur, Hinnerk Schulz-Hildebrandt, Hui Min Leung, Guillermo J. Tearney, Stefanie Krick, Steven M. Rowe, Jarrod W. Barnes

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Elexacaftor/tezacaftor/ivacaftor’s effects on cystic fibrosis infections are maintained, but not increased, after 3.5 years of treatment di Sarah J. Morgan, Ellis Coulter, Hannah L. Betts, George M. Solomon, John P. Clancy, Steven M. Rowe, David P. Nichols, Pradeep K. Singh, the PROMISE-Micro Study Group

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The unfolded protein response affects readthrough of premature termination codons di Yifat S Oren, Michelle L McClure, Steven M Rowe, Eric J Sorscher, Assaf C Bester, Miriam Manor, Eitan Kerem, Joseph Rivlin, Fouad Zahdeh, Matthias Mann, Tamar Geiger, Batsheva Kerem

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Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells di Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

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Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells. di Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M Townes, Steven M Rowe, David M Bedwell, Jennifer Guimbellot, Rui Zhao

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Extracellular vesicles enhance pulmonary transduction of stably associated adeno‐associated virus following intratracheal administration di Gijung Kwak, Olesia Gololobova, Neeraj Sharma, Colin Caine, Marina Mazur, Kathleen Mulka, Natalie E. West, George M. Solomon, Garry R. Cutting, Kenneth W. Witwer, Steven M. Rowe, Michael Paulaitis, George Aslanidi, Jung Soo Suk

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Korean Red Ginseng aqueous extract improves markers of mucociliary clearance by stimulating chloride secretion di Do-Yeon Cho, Daniel Skinner, Shaoyan Zhang, Ahmed Lazrak, Dong Jin Lim, Christopher G. Weeks, Catherine G. Banks, Chang Kyun Han, Si-Kwan Kim, Guillermo J. Tearney, Sadis Matalon, Steven M. Rowe, Bradford A. Woodworth

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Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells di Adrian Constantin Tanjala, Jia Xin Jiang, Paul D. W. Eckford, Mohabir Ramjeesingh, Canhui Li, Ling Jun Huan, Gabrielle Langeveld, Claire Townsend, Daniel V. Paone, Jakob Busch-Petersen, Roman Pekhletski, LiPing Tang, Vamsee Raju, Steven M. Rowe, Christine E. Bear

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Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist di David P. Nichols, Sarah J. Morgan, Michelle Skalland, Anh T. Vo, Jill M. Van Dalfsen, Sachinkumar B.P. Singh, Wendy Ni, Lucas R. Hoffman, Kailee McGeer, Sonya L. Heltshe, John P. Clancy, Steven M. Rowe, Peter Jorth, Pradeep K. Singh, the PROMISE-Micro Study Group

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A ferret model demonstrates sustained fibrosis, restrictive physiology, and airway proximalization di Jacelyn E. Peabody Lever, Qian Li, Nikoleta Pavelkova, Shah S. Hussain, Sayan Bakshi, Janna Q. Ren, Luke I. Jones, Kajal Jadhav, Jared P. Kennemur, Mason Weupe, Javier Campos-Gomez, Liping Tang, Jeremie M. Peabody Lever, Dezhi Wang, Denise D. Stanford, Jeremy B. Foote, Kevin S. Harrod, Harrison Kim, Scott E. Phillips, Steven M. Rowe

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A high‐resolution 3D atlas of the spectrum of tuberculous and COVID‐19 lung lesions di Gordon Wells, Joel N Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj, Leon Y Perumal, Malcolm Matthew, Robert L Hunter, Hayden Pacl, Jacelyn E Peabody Lever, Denise D Stanford, Satinder P Singh, Prachi Bajpai, Upender Manne, Paul V Benson, Steven M Rowe, Stephan le Roux, Alex Sigal, Muofhe Tshibalanganda, Carlyn Wells, Anton du Plessis, Mpumelelo Msimang, Threnesan Naidoo, Adrie J C Steyn

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Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection di Qian Li, Kadambari Vijaykumar, Scott E. Phillips, Shah S. Hussain, Nha V. Huynh, Courtney M. Fernandez-Petty, Jacelyn E. Peabody Lever, Jeremy B. Foote, Janna Ren, Javier Campos-Gómez, Farah Abou Daya, Nathaniel W. Hubbs, Harrison Kim, Ezinwanne Onuoha, Evan R. Boitet, Lianwu Fu, Hui Min Leung, Linhui Yu, Thomas W. Detchemendy, Levi T. Schaefers, Jennifer L. Tipper, Lloyd J. Edwards, Sixto M. Leal Jr., Kevin S. Harrod, Guillermo J. Tearney, Steven M. Rowe

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