Hakutulokset - Stephen Safe

Natural products as anticancer agents and enhancing their efficacy by a mechanism-based precision approach Tekijä Stephen Safe

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725 Immunomodulation by targeting PDL-1 in colon cancer using nuclear receptor 4A1 (NR4A1) antagonists Tekijä Maen Abdelrahim, Kumaravel Mohankumar, Keshav Karki, Stephen Safe

Editorial: Emerging anti-cancer compounds and immunomodulators for pancreatic cancer treatment Tekijä Kathleen E. DelGiorno, Stephen Safe, Jennifer M. Bailey-Lundberg

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Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors. Tekijä Satya Pathi, Indira Jutooru, Gayathri Chadalapaka, Vijayalekshmi Nair, Syng-Ook Lee, Stephen Safe

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Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1) Tekijä Lei Zhang, Greg Martin, Kumaravel Mohankumar, Gus A. Wright, Fuada Mariyam, Stephen Safe

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Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells Tekijä Hyo-Seon Lee, Soo-Hyun Kim, Bo-Mi Kim, Stephen Safe, Syng-Ook Lee

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732 A novel nuclear receptor 4A1 (NR4A1) antagonists attenuates T-cell exhaustion in colorectal cancer Tekijä Maen Abdelrahim, Kumaravel Mohankumar, Stephen Safe, Gus Wright, Subhashree Kumaravel, Rupesh Shrestha, Robert Chapkin

Activation of COUP-TFI by a Novel Diindolylmethane Derivative Tekijä Kyungsil Yoon, Chien-Cheng Chen, Asuka A. Orr, Patricia N. Barreto, Phanourios Tamamis, Stephen Safe

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Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization. Tekijä Wei Ying, Srikanth Kanameni, Cheng-An Chang, Vijayalekshmi Nair, Stephen Safe, Fuller W Bazer, Beiyan Zhou

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Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma. Tekijä Erik Hedrick, Syng-Ook Lee, Gyungeun Kim, Maen Abdelrahim, Un-Ho Jin, Stephen Safe, Ala Abudayyeh

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Flavonoids kaempferol and quercetin are nuclear receptor 4A1 (NR4A1, Nur77) ligands and inhibit rhabdomyosarcoma cell and tumor growth Tekijä Rupesh Shrestha, Kumaravel Mohankumar, Greg Martin, Amanuel Hailemariam, Syng-ook Lee, Un-ho Jin, Robert Burghardt, Stephen Safe

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Synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,-12-dien-30-oate and erlotinib on erlotinib-resistant non-small cell lung cancer cells Tekijä Ebony Nottingham, Elizabeth Mazzio, Sunil Kumar Surapaneni, Shallu Kutlehria, Arindam Mondal, Ramesh Badisa, Stephen Safe, Arun K. Rishi, Mandip Singh

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Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1). Tekijä Cedar H A Boakye, Ravi Doddapaneni, Punit P Shah, Apurva R Patel, Chandraiah Godugu, Stephen Safe, Santosh K Katiyar, Mandip Singh

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A Chalcone Synthase-like Bacterial Protein Catalyzes Heterocyclic C-Ring Cleavage of Naringenin to Alter Bioactivity Against Nuclear Receptors in Colonic Epithelial Cells Tekijä Ebru Ece Gülşan, Farrhin Nowshad, Meredith Davis Leigh, Jimmy Walter Crott, Hyejin Park, Greg Martin, Stephen Safe, Robert S. Chapkin, Arul Jayaraman, Kyongbum Lee

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Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands Tekijä Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen Safe

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Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer. Tekijä Yating Cheng, Parisa Imanirad, Indira Jutooru, Erik Hedrick, Un-Ho Jin, Aline Rodrigues Hoffman, Jeann Leal de Araujo, Benjamin Morpurgo, Andrei Golovko, Stephen Safe

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Orphan nuclear receptor 4A1 (NR4A1) and NR4A2 are endogenous regulators of CD71 and their ligands induce ferroptosis in breast cancer Tekijä Arafat Rahman Oany, Srijana Upadhyay, Wai Ning Tiffany Tsui, Amanuel Hailemariam, Sarah Latka, John D. Landua, Sandra D. Scherer, Alana L. Welm, Hugo Villanueva, Michael T. Lewis, Stephen Safe

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The Transcriptional Repressor ZBTB4 Regulates EZH2 Through a MicroRNA-ZBTB4-Specificity Protein Signaling Axis Tekijä Won Seok Yang, Gayathri Chadalapaka, Sung-Gook Cho, Syng-ook Lee, Un-Ho Jin, Indira Jutooru, Kwangmin Choi, Yuet-Kin Leung, Shuk-Mei Ho, Stephen Safe, Kyounghyun Kim

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Environmental levels and toxicological potencies of a novel mixed halogenated carbazole Tekijä Miren Pena-Abaurrea, Matthew Robson, Sri Chaudhuri, Nicole Riddell, Robert McCrindle, Brock Chittim, Robert Parette, Un-Ho Jin, Stephen Safe, David Poirier, Ralph Ruffolo, Richard Dyer, Rachael Fletcher, Paul A. Helm, Eric J. Reiner

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