Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymer–drug conjugate

بواسطة Chipman, Stewart D, Oldham, Fred B, Pezzoni, Gabriella, Singer, Jack W
منشور في 2006

Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis

بواسطة Al-Fayoumi, Suliman, Hashiguchi, Taishi, Shirakata, Yuka, Mascarenhas, John, Singer, Jack W
الحاوية / القاعدة J Exp Pharmacol (2018)

Comparative phenotypic profiling of the JAK2 inhibitors ruxolitinib, fedratinib, momelotinib, and pacritinib reveals distinct mechanistic signatures

بواسطة Singer, Jack W., Al-Fayoumi, Suliman, Taylor, Jason, Velichko, Sharlene, O’Mahony, Alison
الحاوية / القاعدة PLoS One (2019)

Comprehensive kinase profile of pacritinib, a nonmyelosuppressive Janus kinase 2 inhibitor

بواسطة Singer, Jack W, Al-Fayoumi, Suliman, Ma, Haiching, Komrokji, Rami S, Mesa, Ruben, Verstovsek, Srdan
الحاوية / القاعدة J Exp Pharmacol (2016)

Phase 1/2 study of pacritinib, a next generation JAK2/FLT3 inhibitor, in myelofibrosis or other myeloid malignancies

بواسطة Verstovsek, Srdan, Odenike, Olatoyosi, Singer, Jack W., Granston, Tanya, Al-Fayoumi, Suliman, Deeg, H. Joachim
الحاوية / القاعدة J Hematol Oncol (2016)

Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy

بواسطة Singer, Jack W., Fleischman, Angela, Al-Fayoumi, Suliman, Mascarenhas, John O., Yu, Qiang, Agarwal, Anupriya
الحاوية / القاعدة Oncotarget (2018)

Procoagulant inhibitory properties of paclitaxel poliglumex

بواسطة Nemunaitis, John, Senzer, Neil, Cooper, Barry, Nemunaitis, Michael, Bedell, Cynthia, Singer, Jack W, Oldham, Fred B
منشور في 2010

Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

بواسطة Leung, David W, Tompkins, Chris, Brewer, Jim, Ball, Alexey, Coon, Mike, Morris, Valerie, Waggoner, David, Singer, Jack W
منشور في 2004

Polycythemia Vera: FURTHER IN VITRO STUDIES OF HEMATOPOIETIC REGULATION

بواسطة Adamson, John W., Singer, Jack W., Catalano, Pat, Murphy, Scott, Lin, Nancy, Steinmann, Laura, Ernst, Connie, Fialkow, Philip J.
منشور في 1980

Colony-stimulating Factor-1 Receptor is Required for Nurse-like Cell Survival in Chronic Lymphocytic Leukemia

بواسطة Polk, Avery, Lu, Ye, Wang, Tianjiao, Seymour, Erlene, Bailey, Nathanael G., Singer, Jack W., Boonstra, Philip S., Lim, Megan S., Malek, Sami, Wilcox, Ryan A.
الحاوية / القاعدة Clin Cancer Res (2016)

Monotherapy with pixantrone in histologically confirmed relapsed or refractory aggressive B‐cell non‐Hodgkin lymphoma: post‐hoc analyses from a phase III trial

بواسطة Pettengell, Ruth, Sebban, Catherine, Zinzani, Pier Luigi, Derigs, Hans Gunter, Kravchenko, Sergey, Singer, Jack W., Theocharous, Panteli, Wang, Lixia, Pavlyuk, Mariya, Makhloufi, Kahina M., Coiffier, Bertrand
الحاوية / القاعدة Br J Haematol (2016)

Predictive models for splenic response to JAK-inhibitor therapy in patients with myelofibrosis

بواسطة Menghrajani, Kamal, Boonstra, Philip S., Mercer, Jessica A., Perkins, Cecelia, Gowin, Krisstina L., Weber, Alissa A., Mesa, Ruben, Gotlib, Jason R., Wang, Lixia, Singer, Jack W., Talpaz, Moshe
الحاوية / القاعدة Leuk Lymphoma (2018)

Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial

بواسطة Mascarenhas, John, Hoffman, Ronald, Talpaz, Moshe, Gerds, Aaron T., Stein, Brady, Gupta, Vikas, Szoke, Anita, Drummond, Mark, Pristupa, Alexander, Granston, Tanya, Daly, Robert, Al-Fayoumi, Suliman, Callahan, Jennifer A., Singer, Jack W., Gotlib, Jason, Jamieson, Catriona, Harrison, Claire, Mesa, Ruben, Verstovsek, Srdan
الحاوية / القاعدة JAMA Oncol (2018)

Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes

بواسطة Hosseini, Mona M., Kurtz, Stephen E., Abdelhamed, Sherif, Mahmood, Shawn, Davare, Monika A., Kaempf, Andy, Elferich, Johannes, McDermott, Jason E., Liu, Tao, Payne, Samuel H., Shinde, Ujwal, Rodland, Karin D., Mori, Motomi, Druker, Brian J., Singer, Jack W., Agarwal, Anupriya
الحاوية / القاعدة Leukemia (2018)

Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

بواسطة Mesa, Ruben A, Vannucchi, Alessandro M, Mead, Adam, Egyed, Miklos, Szoke, Anita, Suvorov, Aleksandr, Jakucs, Janos, Perkins, Andrew, Prasad, Ritam, Mayer, Jiri, Demeter, Judit, Ganly, Peter, Singer, Jack W, Zhou, Huafeng, Dean, James P, te Boekhorst, Peter A, Nangalia, Jyoti, Kiladjian, Jean-Jacques, Harrison, Claire N
الحاوية / القاعدة Lancet Haematol (2017)