Výsledky vyhledávání - Sebastien Malinge

Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia Autor Cécile Thirant, Cécile Lopez, Sébastien Malinge, Thomas Mercher

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Characterization of mesenchymal stem cells in pre-B acute lymphoblastic leukemia Autor Anastasia M. Hughes, Anastasia M. Hughes, Vincent Kuek, Vincent Kuek, Vincent Kuek, Joyce Oommen, Grace-Alyssa Chua, Maria van Loenhout, Sebastien Malinge, Sebastien Malinge, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha, Laurence C. Cheung, Laurence C. Cheung, Laurence C. Cheung

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Pharmacological inhibition of sclerostin protects bone from B‐cell acute lymphoblastic leukemia‐mediated destruction Autor Vincent Kuek, Joyce Oommen, Emanuela Ferrari, Jinbo Yuan, Aris N. Economides, Richard B. Lock, Sebastien Malinge, Rishi S. Kotecha, Laurence C. Cheung

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Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic... Autor Laurence C. Cheung, Mark N. Cruickshank, Anastasia M. Hughes, Sajla Singh, Grace-Alyssa Chua, Jette Ford, Emanuela Ferrari, Joyce Oommen, Sébastien Malinge, Richard B. Lock, Ursula R. Kees, Rishi S. Kotecha

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Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models Autor Paola Rivera-Munoz, Anouchka P. Laurent, Aurelie Siret, Cecile K. Lopez, Cathy Ignacimouttou, Melanie G. Cornejo, Olivia Bawa, Philippe Rameau, Olivier A. Bernard, Philippe Dessen, Gary D. Gilliland, Thomas Mercher, Sébastien Malinge

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Down syndrome and leukemia: from basic mechanisms to clinical advances Autor André Baruchel, Jean-Pierre Bourquin, John Crispino, Sergi Cuartero, Henrik Hasle, Johann Hitzler, Jan-Henning Klusmann, Shai Izraeli, Andrew A. Lane, Sébastien Malinge, Karen R. Rabin, Irene Roberts, Sandra Ryeom, Sarah K. Tasian, Elvin Wagenblast

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Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia Autor Laurence C. Cheung, Laurence C. Cheung, Rebecca de Kraa, Joyce Oommen, Grace-Alyssa Chua, Sajla Singh, Anastasia M. Hughes, Emanuela Ferrari, Jette Ford, Sung K. Chiu, Ronald W. Stam, Ursula R. Kees, Sébastien Malinge, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha

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Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia Autor Rishi S. Kotecha, Sarah M. Trinder, Anastasia M. Hughes, Benjamin H. Mullin, Sarah Rashid, Jinbo Yuan, Jiake Xu, Owen Duncan, Patrycja Skut, Grace-Alyssa Chua, Sajla Singh, Joyce Oommen, Richard B. Lock, Ursula R. Kees, Sebastien Malinge, Vincent Kuek, Laurence C. Cheung

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The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300‐dependent stemness program Autor Alexandre Fagnan, Zakia Aid, Marie Baille, Aneta Drakul, Elie Robert, Cécile K. Lopez, Cécile Thirant, Yann Lecluse, Julie Rivière, Cathy Ignacimouttou, Silvia Salmoiraghi, Eduardo Anguita, Audrey Naimo, Christophe Marzac, Françoise Pflumio, Sébastien Malinge, Christian Wichmann, Yun Huang, Camille Lobry, Julie Chaumeil, Eric Soler, Jean‐Pierre Bourquin, Claus Nerlov, Olivier A. Bernard, Juerg Schwaller, Thomas Mercher

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Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model Autor Brahim Arkoun, Elie Robert, Fabien Boudia, Stefania Mazzi, Virginie Dufour, Aurélie Siret, Yasmine Mammasse, Zakia Aid, Matthieu Vieira, Aygun Imanci, Marine Aglave, Marie Cambot, Rachel Petermann, Sylvie Souquere, Philippe Rameau, Cyril Catelain, Romain Diot, Gérard Tachdjian, Olivier Hermine, Nathalie Droin, Najet Debili, Isabelle Plo, Sébastien Malinge, Eric Soler, Hana Raslova, Thomas Mercher, William Vainchenker

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Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia Autor Shannon L. Carey-Smith, Maryam H. Simad, Kunjal Panchal, Carlos Aya-Bonilla, Hannah Smolders, Sang Lin, Jesse D. Armitage, Vivien T. Nguyen, Kathryn Bentley, Jette Ford, Sajla Singh, Joyce Oommen, Anouchka P. Laurent, Thomas Mercher, John D. Crispino, Andrew P. Montgomery, Michael Kassiou, Thierry Besson, Emmanuel Deau, Laurent Meijer, Laurence C. Cheung, Rishi S. Kotecha, Sébastien Malinge

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A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors Autor Maria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, Robin Droit, Wan Ching Lim, Antonin Marchais, Jerome Salmon, Sarah Cherkaoui, Raphael J. Morscher, Anouchka Laurent, Sébastien Malinge, Thomas Mercher, Séverine Tabone-Eglinger, Isabelle Goddard, Francoise Pflumio, Julien Calvo, Francoise Redini, Natacha Entz-Werlé, Aroa Soriano, Alberto Villanueva, Stefano Cairo, Pascal Chastagner, Massimo Moro, Cormac Owens, Michela Casanova, Raquel Hladun-Alvaro, Pablo Berlanga, Estelle Daudigeos-Dubus, Philippe Dessen, Laurence Zitvogel, Ludovic Lacroix, Gaelle Pierron, Olivier Delattre, Gudrun Schleiermacher, Didier Surdez, Birgit Geoerger

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