IDENTIFICATION OF KEY AMINO ACIDS RESPONSIBLE FOR THE SUBSTANTIALLY HIGHER AFFINITIES OF HUMAN TYPE 1 3β-HYDROXYSTEROID DEHYDROGENASE/ISOMERASE (3β-HSD1) FOR SUBSTRATES, COENZYMES...

por Thomas, James L., Boswell, Elizabeth L., Scaccia, Launa A., Pletnev, Vladimir, Umland, Timothy C.
Publicado 2005

Structure/function of human type 1 3β-hydroxysteroid dehydrogenase: an intrasubunit disulfide bond in the Rossmann-fold domain and a Cys residue in the active site are critical for...

por Thomas, James L., Huether, Robert, Mack, Vance L., Scaccia, Launa A., Stoner, Ryan C., Duax, William L.
Publicado 2007

RATIONAL PROTEOMICS V: STRUCTURE-BASED MUTAGENESIS HAS REVEALED KEY RESIDUES RESPONSIBLE FOR SUBSTRATE RECOGNITION AND CATALYSIS BY THE DEHYDROGENASE AND ISOMERASE ACTIVITIES IN HU...

por Pletnev, Vladimir Z., Thomas, James L., Rhaney, Felicia L., Holt, Lynley S., Scaccia, Launa A., Umland, Timothy C., Duax, William L.
Publicado 2006