Resultados da busca - Sabina Signoretti

Regulation of HHLA2 expression in kidney cancer and myeloid cells por Tomonari Shigemura, Nahuel Perrot, Zimo Huang, Rupal S. Bhatt, Aseman Bagheri Sheshdeh, Nourhan El Ahmar, Fatme Ghandour, Sabina Signoretti, David F. McDermott, Gordon J. Freeman, Kathleen M. Mahoney

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A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis por Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg, Massimo Loda

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A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis por Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg, Massimo Loda

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Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma. por Lana Hamieh, Toni K Choueiri, Barbara Ogórek, Damir Khabibullin, Daniel Rosebrock, Dimitri Livitz, Andre Fay, Jean-Christophe Pignon, David F McDermott, Neeraj Agarwal, Wenhua Gao, Sabina Signoretti, David J Kwiatkowski

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Long-term outcomes with nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma por Chung-Wei Lee, Thomas Powles, Sabina Signoretti, Sumanta K Pal, Toni K Choueiri, Brian I Rini, Saby George, Robert J Motzer, Frede Donskov, Scott S Tykodi, Nizar M Tannir, Saurabh Gupta, Ruiyun Jiang

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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases por Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

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1017 SLAMF7+ CD8+ exhausted T cell-specific gene signature is associated with resistance to PD1 blockade in renal cell carcinoma por Michael Hurwitz, Elizabeth Plimack, Jeffrey Sosman, Sabina Signoretti, David F McDermott, Michael B Atkins, Naomi B Haas, Hans Hammers, Nicholas Schindler, Opeyemi A Jegede, Catherine J Wu, David Braun, Miya Hugaboom, Kelly Street, Neil Ruthen, Lena Wirth

Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model por Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, Alicia Buck, Cecile Razimbaud, Aedin C. Culhane, Jiusong Sun, David A. Braun, Toni K. Choueiri, Catherine J. Wu, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Quan Zhu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of renal cell carcinoma, version 3.0 por Tian Zhang, Shankar Siva, Wenxin Xu, Thomas Powles, Sabina Signoretti, Michael B Atkins, Sumanta K Pal, Rana R McKay, Toni K Choueiri, Brian I Rini, A Ari Hakimi, Brian Shuch, Arpita Desai, Pedro C Barata, Archana Ajmera, Cristiane Bergerot, Laura Bukavina, Susan Poteat, Wesley Yip

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1511 Pan-tumor harmonization of pathologic response assessment for standardized data collection in neoadjuvant IO trials (PATHdata): Interim analysis of a multi-institutional repro... por Xiaowei Xu, Hao Wang, Michael Tetzlaff, James Ziai, Sabina Signoretti, Ashley Cimino-Mathews, Tricia Cottrell, Janis M Taube, Annikka Weissferdt, Richard A Scolyer, Pierre-Olivier Fiset, Jaime Rodriguez-Canales, Lynette M Sholl, Julie S Deutsch, Krista Chen, Carlos E de Andrea, Christine Orr, Salgado Roberto, Christian Schurch, Raja Seethala, Alexander S Baras

Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma por Neeraj Agarwal, Sabina Signoretti, David F McDermott, Toni K Choueiri, Wanling Xie, John A Steinharter, Nieves Martinez-Chanza, Bradley A McGregor, Lauren C Harshman, Abhishek Tripathi, Xiao X Wei, Edwin Lin, Abdallah Flaifel, Emily N Stern Gatof, Gabrielle Bouchard, Justin H Fleischer, Connor Gray, Charlene Mantia, Linda Thompson, Marios Giannakis

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Generation of a comprehensive epigenomic atlas in clear cell renal cell carcinoma informs kidney cancer progression and heritability por Sarah Abou Alaiwi, Elio Adib, Ziwei Zhang, Sandor Spisak, Aurel Prosz, Paulo Cordeiro, Talal El Zarif, Zsófia Márta Sztupinszki, Amin H. Nassar, Ji-Heui Seo, Rianna Campbell, John A. Steinharter, Mitchell Machiela, Diptavo Dutta, Stephen Chanock, Mark Purdue, Mark Pomerantz, Sabina Signoretti, Zoltan Szallasi, Alexander Gusev, Sylvan C. Baca, Toni K. Choueiri, Matthew L. Freedman

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The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs por Treg Grubb, Pooneh Koochaki, Sayed Matar, Fatme Ghandour, Marc Machaalani, Eddy Saad, Cerise Tang, Eduard Reznik, Jesminara Khatun, Carleigh Salem, Noah Dubasik, David A. Orlando, Matthew G. Guenther, Gyanu Parajuli, Raghvendra M. Srivastava, Steven R. Martinez, Jesse A. Coker, Ritesh R. Kotecha, A. Ari Hakimi, John M. Asara, Timothy A. Chan, Sakari Vanharanta, Shaun R. Stauffer, William G. Kaelin, Sabina Signoretti, Toni K. Choueiri, Abhishek A. Chakraborty

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Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects por Yufei Wang, Alicia Buck, Brandon Piel, Luann Zerefa, Nithyassree Murugan, Christian D. Coherd, Andras G. Miklosi, Haraman Johal, Ricardo Nunes Bastos, Kun Huang, Miriam Ficial, Yasmin Nabil Laimon, Sabina Signoretti, Zhou Zhong, Song-My Hoang, Gabriella M. Kastrunes, Marion Grimaud, Atef Fayed, Hsien-Chi Yuan, Quang-De Nguyen, Tran Thai, Elena V. Ivanova, Cloud P. Paweletz, Ming-Ru Wu, Toni K. Choueiri, Jon O. Wee, Gordon J. Freeman, David A. Barbie, Wayne A. Marasco

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Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma por Talal El Zarif, Karl Semaan, Marc Eid, Ji-Heui Seo, Simon Garinet, Matthew P. Davidsohn, Pranshu Sahgal, Brad Fortunato, John Canniff, Amin H. Nassar, Sarah Abou Alaiwi, Ziad Bakouny, Gitanjali Lakshminarayanan, Hunter Savignano, Kevin Lyons, Sayed Matar, Atef Ali, Eddy Saad, Renee Maria Saliby, Paulo Cordeiro, Ziwei Zhang, Nourhan El Ahmar, Yasmin Nabil Laimon, Chris Labaki, Valisha Shah, Dory Freeman, Jillian O’Toole, Gwo-Shu Mary Lee, Justin Hwang, Mark Pomerantz, Sabina Signoretti, Eliezer M. Van Allen, Wanling Xie, Jacob E. Berchuck, Srinivas R. Viswanathan, David A. Braun, Toni K. Choueiri, Matthew L. Freedman, Sylvan C. Baca

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The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma por Christopher J. Ricketts, Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, Ewan A. Gibb, Rehan Akbani, Rameen Beroukhim, Donald P. Bottaro, Toni K. Choueiri, Richard A. Gibbs, Andrew K. Godwin, Scott Haake, A. Ari Hakimi, Elizabeth P. Henske, James J. Hsieh, Thai H. Ho, Rupa S. Kanchi, Bhavani Krishnan, David J. Kwiatkowski, Wenbin Liu, Maria J. Merino, Gordon B. Mills, Jerome Myers, Michael L. Nickerson, Victor E. Reuter, Laura S. Schmidt, C. Simon Shelley, Hui Shen, Brian Shuch, Sabina Signoretti, Ramaprasad Srinivasan, Pheroze Tamboli, George Thomas, Benjamin G. Vincent, Cathy D. Vocke, David A. Wheeler, Lixing Yang, William Y. Kim, A. Gordon Robertson, Paul T. Spellman, W. Kimryn Rathmell, W. Marston Linehan

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