Catalytic in vivo protein knockdown by small-molecule PROTACs

by Bondeson, Daniel P, Mares, Alina, Smith, Ian E D, Ko, Eunhwa, Campos, Sebastien, Miah, Afjal H, Mulholland, Katie E, Routly, Natasha, Buckley, Dennis L, Gustafson, Jeffrey L, Zinn, Nico, Grandi, Paola, Shimamura, Satoko, Bergamini, Giovanna, Faelth-Savitski, Maria, Bantscheff, Marcus, Cox, Carly, Gordon, Deborah A, Willard, Ryan R, Flanagan, John J, Casillas, Linda N, Votta, Bartholomew J, den Besten, Willem, Famm, Kristoffer, Kruidenier, Laurens, Carter, Paul S, Harling, John D, Churcher, Ian, Crews, Craig M
Published in Nat Chem Biol (2015)