Search Results - Rachel Brough

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  1. 1

    Synthetic lethality of PARP and NAMPT inhibition in triple‐negative breast cancer cells by Ilirjana Bajrami, Asha Kigozi, Antoinette Van Weverwijk, Rachel Brough, Jessica Frankum, Christopher J. Lord, Alan Ashworth

    Published 2012-08-01
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  2. 2

    CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours. by Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth

    Published 2016-01-01
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  3. 3

    A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity. by Stephen J Pettitt, Farah L Rehman, Ilirjana Bajrami, Rachel Brough, Fredrik Wallberg, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Lina Chen, James Campbell, Christopher J Lord, Alan Ashworth

    Published 2013-01-01
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  4. 4

    Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7 by Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

    Published 2024-02-01
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  5. 5

    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells by Anabel Zelceski, Paola Francica, Lea Lingg, Merve Mutlu, Colin Stok, Martin Liptay, John Alexander, Joseph S. Baxter, Rachel Brough, Aditi Gulati, Syed Haider, Maya Raghunandan, Feifei Song, Sandhya Sridhar, Josep V. Forment, Mark J. O’Connor, Barry R. Davies, Marcel A.T.M. van Vugt, Dragomir B. Krastev, Stephen J. Pettitt, Andrew N.J. Tutt, Sven Rottenberg, Christopher J. Lord

    Published 2023-05-01
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  6. 6

    Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers by Roman M. Chabanon, Liudmila Shcherbakova, Magali Lacroix-Triki, Marine Aglave, Jean Zeghondy, Victor Kriaa, Antoine Gougé, Marlène Garrido, Elodie Edmond, Ludovic Bigot, Dragomir B. Krastev, Rachel Brough, Stephen J. Pettitt, Thibault Thomas-Bonafos, Robert Samstein, Christophe Massard, Marc Deloger, Andrew NJ Tutt, Fabrice Barlesi, Yohann Loriot, Suzette Delaloge, Marcel Tawk, Cindy Degerny, Yea-Lih Lin, Barbara Pistilli, Philippe Pasero, Christopher J. Lord, Sophie Postel-Vinay

    Published 2025-07-01
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  7. 7

    CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13 by Jean Ching-Yi Tien, Jie Luo, Yu Chang, Yuping Zhang, Yunhui Cheng, Xiaoju Wang, Jianzhang Yang, Rahul Mannan, Somnath Mahapatra, Palak Shah, Xiao-Ming Wang, Abigail J. Todd, Sanjana Eyunni, Caleb Cheng, Ryan J. Rebernick, Lanbo Xiao, Yi Bao, James Neiswender, Rachel Brough, Stephen J. Pettitt, Xuhong Cao, Stephanie J. Miner, Licheng Zhou, Yi-Mi Wu, Estefania Labanca, Yuzhuo Wang, Abhijit Parolia, Marcin Cieslik, Dan R. Robinson, Zhen Wang, Felix Y. Feng, Jonathan Chou, Christopher J. Lord, Ke Ding, Arul M. Chinnaiyan

    Published 2024-10-01
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