Transcriptional and epigenetic regulation of macrophages in atherosclerosis

著者: Kuznetsova, Tatyana, Prange, Koen H.M., Glass, Christopher K., De Winther, Menno P.J.
出版年 Nat Rev Cardiol (2019)

AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis

著者: Singh, Abhishek A., Mandoli, Amit, Prange, Koen H.M., Laakso, Marko, Martens, Joost H.A.
出版年 Oncotarget (2016)

Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotei...

著者: Stiekema, Lotte C A, Prange, Koen H M, Hoogeveen, Renate M, Verweij, Simone L, Kroon, Jeffrey, Schnitzler, Johan G, Dzobo, Kim E, Cupido, Arjen J, Tsimikas, Sotirios, Stroes, Erik S G, de Winther, Menno P J, Bahjat, Mahnoush
出版年 Eur Heart J (2020)

Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss

著者: Willemsen, Lisa, Neele, Annette E, van der Velden, Saskia, Prange, Koen H M, den Toom, Myrthe, van Roomen, Cindy P A A, Reiche, Myrthe E, Griffith, Guillermo R, Gijbels, Marion J J, Lutgens, Esther, de Winther, Menno P J
出版年 BMJ Open Diabetes Res Care (2019)

Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation

著者: Schnitzler, Johan G., Hoogeveen, Renate M., Ali, Lubna, Prange, Koen H.M., Waissi, Farahnaz, van Weeghel, Michel, Bachmann, Julian C., Versloot, Miranda, Borrelli, Matthew J., Yeang, Calvin, De Kleijn, Dominique P.V., Houtkooper, Riekelt H., Koschinsky, Marlys L., de Winther, Menno P.J., Groen, Albert K., Witztum, Joseph L., Tsimikas, Sotirios, Stroes, Erik S.G., Kroon, Jeffrey
出版年 Circ Res (2020)

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

著者: Depuydt, Marie A.C., Prange, Koen H.M., Slenders, Lotte, Örd, Tiit, Elbersen, Danny, Boltjes, Arjan, de Jager, Saskia C.A., Asselbergs, Folkert W., de Borst, Gert J., Aavik, Einari, Lönnberg, Tapio, Lutgens, Esther, Glass, Christopher K., den Ruijter, Hester M., Kaikkonen, Minna U., Bot, Ilze, Slütter, Bram, van der Laan, Sander W., Yla-Herttuala, Seppo, Mokry, Michal, Kuiper, Johan, de Winther, Menno P.J., Pasterkamp, Gerard
出版年 Circ Res (2020)

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

著者: Baardman, Jeroen, Verberk, Sanne G. S., van der Velden, Saskia, Gijbels, Marion J. J., van Roomen, Cindy P. P. A., Sluimer, Judith C., Broos, Jelle Y., Griffith, Guillermo R., Prange, Koen H. M., van Weeghel, Michel, Lakbir, Soufyan, Molenaar, Douwe, Meinster, Elisa, Neele, Annette E., Kooij, Gijs, de Vries, Helga E., Lutgens, Esther, Wellen, Kathryn E., de Winther, Menno P. J., Van den Bossche, Jan
出版年 Nat Commun (2020)

Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

著者: Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
出版年 Nat Commun (2021)

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

著者: Yi, Guoqiang, Wierenga, Albertus T.J., Petraglia, Francesca, Narang, Pankaj, Janssen-Megens, Eva M., Mandoli, Amit, Merkel, Angelika, Berentsen, Kim, Kim, Bowon, Matarese, Filomena, Singh, Abhishek A., Habibi, Ehsan, Prange, Koen H.M., Mulder, André B., Jansen, Joop H., Clarke, Laura, Heath, Simon, van der Reijden, Bert A., Flicek, Paul, Yaspo, Marie-Laure, Gut, Ivo, Bock, Christoph, Schuringa, Jan Jacob, Altucci, Lucia, Vellenga, Edo, Stunnenberg, Hendrik G., Martens, Joost H.A.
出版年 Cell Rep (2019)