Zoekresultaten - Prajwal Rajappa

406 Reprogramming the glioma immunosuppressive tumor microenvironment with engineered myeloid cells that release IL-2 to delay malignant progression door Matthew Nazzaro, Alessandro Canella, Claire Schmitt, Abigail Haffey, Giovanni Nigita, Gregory K Behbehani, Prajwal Rajappa

Primary murine high-grade glioma cells derived from RCAS/tv-a diffuse glioma model reprogram naive T cells into immunosuppressive regulatory T lymphocytes door Alessandro Canella, Mykyta Artomov, Aleksandr Ukhatov, Sakthi Rajendran, Phillip Perez, Uksha Saini, Jack Hedberg, Kevin Cassady, Prajwal Rajappa

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In vitro generated macrophages reflect the immunosuppressive phenotype of in vivo glioblastoma-associated macrophages door Matthew Nazzaro, Elaine R. Mardis, Mykyta Artomov, Ella Juenger, Justin Lyberger, Mark Damante, Gregory Behbehani, Susobhan Sarkar, Prajwal Rajappa

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Trabectedin decreases myeloid resistance to improve the efficacy of anti-PD1 immunotherapy and delay glioma malignant progression door Matthew Nazzaro, Elaine R. Mardis, Alessandro Canella, Bhavneet Bhinder, Olivier Elemento, Gregory Behbehani, Mark Currier, Andrea Glaspell, Dean A. Lee, Timothy P. Cripe, Prajwal Rajappa

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Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment door Alessandro Canella, Matthew Nazzaro, Sakthi Rajendran, Claire Schmitt, Abigail Haffey, Giovanni Nigita, Diana Thomas, Justin M. Lyberger, Gregory K. Behbehani, Nduka M. Amankulor, Elaine R. Mardis, Timothy P. Cripe, Prajwal Rajappa

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BRAF V600E in a preclinical model of pleomorphic Xanthoastrocytoma: Analysis of the tumor microenvironment and immune cell infiltration dynamics in vivo door Alessandro Canella, Matthew Nazzaro, Mykyta Artomov, Lakshmi Prakruthi Rao Venkata, Diana Thomas, Justin Lyberger, Aleksandr Ukhatov, Yao Lulu Xing, Katherine Miller, Gregory Behbehani, Nduka M. Amankulor, Claudia Katharina Petritsch, Prajwal Rajappa

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Trabectedin promotes oncolytic virus antitumor efficacy, viral gene expression, and immune effector function in models of bone sarcoma door Emily M. Ringwalt, Mark A. Currier, Andrea M. Glaspell, Chun-Yu Chen, Matthew V. Cannon, Maren Cam, Amy C. Gross, Matthew Gust, Pin-Yi Wang, Louis Boon, Laura E. Biederman, Emily Schwarz, Prajwal Rajappa, Dean A. Lee, Elaine R. Mardis, William E. Carson, 3rd, Ryan D. Roberts, Timothy P. Cripe

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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma door Sakthi Rajendran, Yang Hu, Alessandro Canella, Clayton Peterson, Amy Gross, Maren Cam, Matthew Nazzaro, Abigail Haffey, Akdes Serin-Harmanci, Rosario Distefano, Giovanni Nigita, Wesley Wang, Daniel Kreatsoulas, Zihai Li, Jesse A. Sepeda, Andrew Sas, Mark E. Hester, Katherine E. Miller, Olivier Elemento, Ryan D. Roberts, Eric C. Holland, Ganesh Rao, Elaine R. Mardis, Prajwal Rajappa

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Safety and Feasibility of Stereotactic Radiosurgery for Patients with 15 or more Brain Metastases door Rituraj Upadhyay, MD, Joshua D. Palmer, MD, Brett G. Klamer, PhD, Haley K. Perlow, MD, Jonathan E. Schoenhals, MD, Jayeeta Ghose, PhD, Prajwal Rajappa, MD, Dukagjin M. Blakaj, MD, PhD, Sasha Beyer, MD, PhD, John C. Grecula, MD, Austin J. Sim, MD, JD, Lanchun Lu, PhD, Wesley Zoller, CMD, James B. Elder, MD, Arnab Chakravarti, MD, Evan Thomas, MD, PhD, Raju R. Raval, MD, DPhil

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The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma door Tyler J. Alban, Matthew M. Grabowski, Balint Otvos, Defne Bayik, Wesley Wang, Ajay Zalavadia, Vlad Makarov, Katie Troike, Mary McGraw, Anja Rabljenovic, Adam Lauko, Chase Neumann, Gustavo Roversi, Kristin A. Waite, Gino Cioffi, Nirav Patil, Thuy T. Tran, Kathleen McCortney, Alicia Steffens, C. Marcela Diaz, J. Mark Brown, Kathleen M. Egan, Craig M. Horbinski, Jill S. Barnholtz-Sloan, Prajwal Rajappa, Michael A. Vogelbaum, Richard Bucala, Timothy A. Chan, Manmeet S. Ahluwalia, Justin D. Lathia

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