Invariant NKT Cells as Novel Targets for Immunotherapy in Solid Tumors

by Pilones, Karsten A., Aryankalayil, Joseph, Demaria, Sandra
Published 2012

Combination of interleukin-15 and fractionated radiotherapy for cancer treatment

by Aryankalayil, Joseph, Pilones, Karsten, Vatner, Ralph, Demaria, Sandra
Published in J Immunother Cancer (2014)

Intratumoral IL-15 potentiates radiation-induced anti-tumor immunity

by Pilones, Karsten, Aryankalayil, Joseph, Formenti, Silvia, Demaria, Sandra
Published in J Immunother Cancer (2015)

Dendritic cells cross-presenting tumor-derived antigens are eliminated by invariant natural killer T (iNKT) cells, impairing development of anti-tumor immunity to a mouse carcinoma

by Pilones, Karsten A, Aryankalayil, Joseph, Formenti, Silvia, Demaria, Sandra
Published 2013

Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes

by Pilones, Karsten A, Aryankalayil, Joseph, Babb, James S, Demaria, Sandra
Published 2014

Unique changes in the TCR repertoire of tumor-infiltrating lymphocytes underlie the synergy of radiotherapy with CTLA-4 blockade

by Pilones, Karsten, Emerson, Ryan, Formenti, Silvia, Robins, Harlan, Demaria, Sandra
Published in J Immunother Cancer (2014)

IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection

by Pilones, Karsten A., Charpentier, Maud, Garcia-Martinez, Elena, Demaria, Sandra
Published in Oncoimmunology (2020)

Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment

by Demaria, Sandra, Pilones, Karsten A., Formenti, Silvia C., Dustin, Michael L.
Published 2013

Radiotherapy induces responsiveness of a resistant mammary carcinoma to PD-1 blockade

by Diamond, Julie, Pilones, Karsten, Aryankalayil, Joseph, Vatner, Ralph, Formenti, Silvia, Demaria, Sandra
Published in J Immunother Cancer (2014)

Mechanisms of synergy of radiotherapy and immunotherapy

by Pilones, Karsten A, Emerson, Ryan, Formenti, Silvia C, Robbins, Harlan S, Demaria, Sandra
Published in J Transl Med (2015)

In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment

by Vanpouille-Box, Claire, Pilones, Karsten A., Wennerberg, Erik, Formenti, Silvia C., Demaria, Sandra
Published in Vaccine (2015)

The Optimal Partnership of Radiation and Immunotherapy: from Preclinical Studies to Clinical Translation

by Demaria, Sandra, Pilones, Karsten A., Vanpouille-Box, Claire, Golden, Encouse B., Formenti, Silvia C.
Published 2014

Fractionated but not single dose radiation releases key signals of in situ tumor vaccination

by Vanpouille-Box, Claire, Aryankalayil, Molykutty, Pilones, Karsten, Formenti, Silvia, Coleman, C Norman, Demaria, Sandra
Published in J Immunother Cancer (2014)

Invariant natural killer T cells regulate breast cancer response to radiation and CTLA-4 blockade

by Pilones, Karsten A., Kawashima, Noriko, Yang, Anne Marie, Babb, James S., Formenti, Silvia C., Demaria, Sandra
Published 2009

CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy

by Pourchet, Aldo, Fuhrmann, Steven R., Pilones, Karsten A., Demaria, Sandra, Frey, Alan B., Mulvey, Matthew, Mohr, Ian
Published in EBioMedicine (2016)

Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade

by Pilones, Karsten A., Hensler, Michal, Daviaud, Camille, Kraynak, Jeffrey, Fucikova, Jitka, Galluzzi, Lorenzo, Demaria, Sandra, Formenti, Silvia C.
Published in Oncoimmunology (2020)

Radiotherapy cooperates with IL15 to induce antitumor immune responses

by Pilones, Karsten A., Charpentier, Maud, Garcia-Martinez, Elena, Daviaud, Camille, Kraynak, Jeffrey, Aryankalayil, Joseph, Formenti, Silvia C., Demaria, Sandra
Published in Cancer Immunol Res (2020)

Barriers to Radiation-Induced In Situ Tumor Vaccination

by Wennerberg, Erik, Lhuillier, Claire, Vanpouille-Box, Claire, Pilones, Karsten A., García-Martínez, Elena, Rudqvist, Nils-Petter, Formenti, Silvia C., Demaria, Sandra
Published in Front Immunol (2017)

TGFβ is a master regulator of radiation therapy-induced anti-tumor immunity

by Vanpouille-Box, Claire, Diamond, Julie M., Pilones, Karsten A., Zavadil, Jiri, Babb, James S., Formenti, Silvia C., Barcellos-Hoff, Mary Helen, Demaria, Sandra
Published in Cancer Res (2015)

Suppressing T cell motility induced by anti–CTLA-4 monotherapy improves antitumor effects

by Ruocco, Maria Grazia, Pilones, Karsten A., Kawashima, Noriko, Cammer, Michael, Huang, Julie, Babb, James S., Liu, Mengling, Formenti, Silvia C., Dustin, Michael L., Demaria, Sandra
Published 2012