The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia

by Shinya Tasaki, Shinya Tasaki, Chris Gaiteri, Chris Gaiteri, Sara Mostafavi, Philip L. De Jager, Philip L. De Jager, David A. Bennett, David A. Bennett
Published 2018-10-01

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

by Calvin Park, Gerald Ponath, Maya Levine-Ritterman, Edward Bull, Eric C. Swanson, Philip L. De Jager, Benjamin M. Segal, David Pitt
Published 2019-08-01

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

by Hansruedi Mathys, Chinnakkaruppan Adaikkan, Fan Gao, Jennie Z. Young, Elodie Manet, Martin Hemberg, Philip L. De Jager, Richard M. Ransohoff, Aviv Regev, Li-Huei Tsai
Published 2017-10-01

Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

by Michiko Sekiya, Minghui Wang, Naoki Fujisaki, Yasufumi Sakakibara, Xiuming Quan, Michelle E. Ehrlich, Philip L. De Jager, David A. Bennett, Eric E. Schadt, Sam Gandy, Kanae Ando, Bin Zhang, Koichi M. Iijima
Published 2018-03-01

Mitochondrial respiratory chain protein co-regulation in the human brain

by Caroline Trumpff, Edward Owusu-Ansah, Hans-Ulrich Klein, Annie J. Lee, Vladislav Petyuk, Thomas S. Wingo, Aliza P. Wingo, Madhav Thambisetty, Luigi Ferrucci, Nicholas T. Seyfried, David A. Bennett, Philip L. De Jager, Martin Picard
Published 2022-05-01

Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.

by Edwin Choy, Roman Yelensky, Sasha Bonakdar, Robert M Plenge, Richa Saxena, Philip L De Jager, Stanley Y Shaw, Cara S Wolfish, Jacqueline M Slavik, Chris Cotsapas, Manuel Rivas, Emmanouil T Dermitzakis, Ellen Cahir-McFarland, Elliott Kieff, David Hafler, Mark J Daly, David Altshuler
Published 2008-11-01

Transcriptome and TCR Repertoire Measurements of CXCR3+ T Follicular Helper Cells Within HIV-Infected Human Lymph Nodes

by Chenfeng He, Michael J. Malone, Michael J. Malone, Ben S. Wendel, Ben S. Wendel, Ke-Yue Ma, Daniel Del Alcazar, Daniel Del Alcazar, David B. Weiner, Philip L. De Jager, Perla M. Del Río-Estrada, Yuria Ablanedo-Terrazas, Gustavo Reyes-Terán, Laura F. Su, Laura F. Su, Ning Jiang, Ning Jiang, Ning Jiang, Ning Jiang
Published 2022-05-01

Life Extension Factor Klotho Enhances Cognition

by Dena B. Dubal, Jennifer S. Yokoyama, Lei Zhu, Lauren Broestl, Kurtresha Worden, Dan Wang, Virginia E. Sturm, Daniel Kim, Eric Klein, Gui-Qiu Yu, Kaitlyn Ho, Kirsten E. Eilertson, Lei Yu, Makoto Kuro-o, Philip L. De Jager, Giovanni Coppola, Gary W. Small, David A. Bennett, Joel H. Kramer, Carmela R. Abraham, Bruce L. Miller, Lennart Mucke
Published 2014-05-01

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.

by Gary W Beecham, Kara Hamilton, Adam C Naj, Eden R Martin, Matt Huentelman, Amanda J Myers, Jason J Corneveaux, John Hardy, Jean-Paul Vonsattel, Steven G Younkin, David A Bennett, Philip L De Jager, Eric B Larson, Paul K Crane, M Ilyas Kamboh, Julia K Kofler, Deborah C Mash, Linda Duque, John R Gilbert, Harry Gwirtsman, Joseph D Buxbaum, Patricia Kramer, Dennis W Dickson, Lindsay A Farrer, Matthew P Frosch, Bernardino Ghetti, Jonathan L Haines, Bradley T Hyman, Walter A Kukull, Richard P Mayeux, Margaret A Pericak-Vance, Julie A Schneider, John Q Trojanowski, Eric M Reiman, Alzheimer's Disease Genetics Consortium (ADGC), Gerard D Schellenberg, Thomas J Montine
Published 2014-09-01

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.

by Yukinori Okada, Dorothee Diogo, Jeffrey D Greenberg, Faten Mouassess, Walid A L Achkar, Robert S Fulton, Joshua C Denny, Namrata Gupta, Daniel Mirel, Stacy Gabriel, Gang Li, Joel M Kremer, Dimitrios A Pappas, Robert J Carroll, Anne E Eyler, Gosia Trynka, Eli A Stahl, Jing Cui, Richa Saxena, Marieke J H Coenen, Henk-Jan Guchelaar, Tom W J Huizinga, Philippe Dieudé, Xavier Mariette, Anne Barton, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, Larry W Moreland, S Louis Bridges, Corinne Miceli-Richard, Hyon K Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, Towfique Raj, Philip L De Jager, Soumya Raychaudhuri, Jane Worthington, Leonid Padyukov, Lars Klareskog, Katherine A Siminovitch, Peter K Gregersen, Elaine R Mardis, Thurayya Arayssi, Layla A Kazkaz, Robert M Plenge
Published 2014-01-01