Mechanisms of resistance to CAR T cell therapies

by Singh, Nathan, Orlando, Elena, Xu, Jun, Xu, Jie, Binder, Zev, Collins, McKensie A., O’Rourke, Donald M., Melenhorst, J. Joseph
Published in Semin Cancer Biol (2019)

Diagnostic accuracy and interobserver variability of CO-RADS in patients with suspected coronavirus disease-2019: a multireader validation study

by Bellini, Davide, Panvini, Nicola, Rengo, Marco, Vicini, Simone, Lichtner, Miriam, Tieghi, Tiziana, Ippoliti, Dea, Giulio, Federica, Orlando, Elena, Iozzino, Mario, Ciolfi, Maria Grazia, Montechiarello, Sarah, d’Ambrosio, Ugo, d’Adamo, Emanuele, Gambaretto, Chiara, Panno, Stefano, Caldon, Vanessa, Ambrogi, Cesare, Carbone, Iacopo
Published in Eur Radiol (2020)

Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of the epigenome

by Zhang, Qian, Orlando, Elena J., Wang, Hong Y., Bogusz, Agata M., Liu, Xiaobin, Lacey, Simon F., Strauser, Honore T., Nunez-Cruz, Selene, Nejati, Reza, Zhang, Paul, Brooks, Sarah, Watt, Christopher, Melenhorst, J. Joseph, June, Carl H., Schuster, Stephen J., Wasik, Mariusz A.
Published in Blood (2020)

Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T cell dysfunction

by Singh, Nathan, Lee, Yong Gu, Shestova, Olga, Ravikumar, Pranali, Hayer, Katharina E., Hong, Seok Jae, Lu, Xueqing Maggie, Pajarillo, Raymone, Agarwal, Sangya, Kuramitsu, Shunichiro, Orlando, Elena J., Mueller, Karen Thudium, Good, Charly R., Berger, Shelley L., Shalem, Ophir, Weitzman, Matthew D., Frey, Noelle V., Maude, Shannon L., Grupp, Stephan A., June, Carl H., Gill, Saar, Ruella, Marco
Published in Cancer Discov (2020)

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

by Ruella, Marco, Xu, Jun, Barrett, David M., Fraietta, Joseph A., Reich, Tyler J., Ambrose, David E., Klichinsky, Michael, Shestova, Olga, Patel, Prachi R., Kulikovskaya, Irina, Nazimuddin, Farzana, Bhoj, Vijay G., Orlando, Elena J., Fry, Terry J., Bitter, Hans, Maude, Shannon L., Levine, Bruce L., Nobles, Christopher L., Bushman, Frederic D., Young, Regina M., Scholler, John, Gill, Saar I., June, Carl H., Grupp, Stephan A., Lacey, Simon F., Melenhorst, J. Joseph
Published in Nat Med (2018)

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

by Fraietta, Joseph A., Lacey, Simon F., Orlando, Elena J., Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C., Wang, Yan, O’Connor, Roddy S., Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E., Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M., Johnson, F. Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H., Davis, Megan M., Levine, Bruce L., Frey, Noelle V., Siegel, Donald L., Huang, Alexander C., Wherry, E. John, Bitter, Hans, Brogdon, Jennifer L., Porter, David L., June, Carl H., Melenhorst, J. Joseph
Published in Nat Med (2018)

Einstein@Home discovers a radio-quiet gamma-ray millisecond pulsar

by Clark, Colin J., Pletsch, Holger J., Wu, Jason, Guillemot, Lucas, Kerr, Matthew, Johnson, Tyrel J., Camilo, Fernando, Salvetti, David, Allen, Bruce, Anderson, David, Aulbert, Carsten, Beer, Christian, Bock, Oliver, Cuéllar, Andres, Eggenstein, Heinz-Bernd, Fehrmann, Henning, Kramer, Michael, Kwang, Shawn A., Machenschalk, Bernd, Nieder, Lars, Ackermann, Markus, Ajello, Marco, Baldini, Luca, Ballet, Jean, Barbiellini, Guido, Bastieri, Denis, Bellazzini, Ronaldo, Bissaldi, Elisabetta, Blandford, Roger D., Bloom, Elliott D., Bonino, Raffaella, Bottacini, Eugenio, Brandt, Terri J., Bregeon, Johan, Bruel, Philippe, Buehler, Rolf, Burnett, Toby H., Buson, Sara, Cameron, Rob A., Caputo, Regina, Caraveo, Patrizia A., Cavazzuti, Elisabetta, Cecchi, Claudia, Charles, Eric, Chekhtman, Alexandre, Ciprini, Stefano, Cominsky, Lynn R., Costantin, Denise, Cutini, Sara, D’Ammando, Filippo, De Luca, Andrea, Desiante, Rachele, Di Venere, Leonardo, Di Mauro, Mattia, Di Lalla, Niccolò, Digel, Seth W., Favuzzi, Cecilia, Ferrara, Elizabeth C., Franckowiak, Anna, Fukazawa, Yasushi, Funk, Stefan, Fusco, Piergiorgio, Gargano, Fabio, Gasparrini, Dario, Giglietto, Nico, Giordano, Francesco, Giroletti, Marcello, Gomez-Vargas, Germán A., Green, David, Grenier, Isabelle A., Guiriec, Sylvain, Harding, Alice K., Hewitt, John W., Horan, Deirdre, Jóhannesson, Guðlaugur, Kensei, Shiki, Kuss, Michael, La Mura, Giovanni, Larsson, Stefan, Latronico, Luca, Li, Jian, Longo, Francesco, Loparco, Francesco, Lovellette, Michael N., Lubrano, Pasquale, Magill, Jeffrey D., Maldera, Simone, Manfreda, Alberto, Mazziotta, Mario N., McEnery, Julie E., Michelson, Peter F., Mirabal, Nestor, Mitthumsiri, Warit, Mizuno, Tsunefumi, Monzani, Maria Elena, Morselli, Aldo, Moskalenko, Igor V., Nuss, Eric, Ohsugi, Takashi, Omodei, Nicola, Orienti, Monica, Orlando, Elena, Palatiello, Michele, Paliya, Vaidehi S., de Palma, Francesco, Paneque, David, Perkins, Jeremy S., Persic, Massimo, Pesce-Rollins, Melissa, Porter, Troy A., Principe, Giacomo, Rainò, Silvia, Rando, Riccardo, Ray, Paul S., Razzano, Massimiliano, Reimer, Anita, Reimer, Olaf, Romani, Roger W., Saz Parkinson, Pablo M., Sgrò, Carmelo, Siskind, Eric J., Smith, David A., Spada, Francesca, Spandre, Gloria, Spinelli, Paolo, Thayer, Jana B., Thompson, David J., Torres, Diego F., Troja, Eleonora, Vianello, Giacomo, Wood, Kent, Wood, Matthew
Published in Sci Adv (2018)