نتائج البحث - Michael Spohn

Transcriptomics-based characterization of the immuno-stromal microenvironment in pediatric low-grade glioma حسب Meik Körner, Michael Spohn, Ulrich Schüller, Michael Bockmayr

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IRF4 is required for migration of CD4+ T cells to the intestine but not for Th2 and Th17 cell maintenance حسب Constantin Schmidt, Constantin Schmidt, Aenne Harberts, Aenne Harberts, Daniel Reimers, Tabea Bertram, Leonie Caroline Voß, Joanna Schmid, Niels Christian Lory, Michael Spohn, Michael Spohn, Michael Spohn, Friedrich Koch-Nolte, Samuel Huber, Friederike Raczkowski, Minka Breloer, Minka Breloer, Hans-Willi Mittrücker

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Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo. حسب Julia S Czechowicz, Claus-Henning Nagel, Maike Voges, Michael Spohn, Martha M Eibl, Joachim Hauber

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Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in mice حسب Leonie Caroline Voß, Constantin Schmidt, Constantin Schmidt, Aenne Harberts, Aenne Harberts, Aenne Harberts, Michael Spohn, Michael Spohn, Michael Spohn, Peter Bradtke, Alina Borchers, Alina Borchers, Alina Borchers, Stefanie Fertig, Joanna Schmid, Friedrich Koch-Nolte, Christian F. Krebs, Christian F. Krebs, Christian F. Krebs, Friederike Raczkowski, Hans-Willi Mittrücker, Hans-Willi Mittrücker

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O5 CRISPR/Cas9-derived activation systems as new tools for induction of latent human immunodeficiency virus (HIV) حسب JuliaK Bialek, Maike Voges, Gabor A. Dunay, Carola Schäfer, Michael Spohn, Joachim Hauber, Ulrike C. Lange

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Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems. حسب Julia K Bialek, Gábor A Dunay, Maike Voges, Carola Schäfer, Michael Spohn, Rolf Stucka, Joachim Hauber, Ulrike C Lange

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Merkel Cell Polyomavirus DNA Replication Induces Senescence in Human Dermal Fibroblasts in a Kap1/Trim28-Dependent Manner حسب Svenja Siebels, Manja Czech-Sioli, Michael Spohn, Claudia Schmidt, Juliane Theiss, Daniela Indenbirken, Thomas Günther, Adam Grundhoff, Nicole Fischer

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Defining Culture Conditions for the Hidden Nitrite-Oxidizing Bacterium Nitrolancea حسب Eva Spieck, Katharina Sass, Sabine Keuter, Sophia Hirschmann, Michael Spohn, Daniela Indenbirken, Linnea F. M. Kop, Sebastian Lücker, Alejandra Giaveno

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Identification of virus-encoded microRNAs in divergent Papillomaviruses. حسب Rachel Chirayil, Rodney P Kincaid, Christine Dahlke, Chad V Kuny, Nicole Dälken, Michael Spohn, Becki Lawson, Adam Grundhoff, Christopher S Sullivan

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Characterization of a PRKCE::ETV6 fusion as a potential oncogenic driver in T-cell acute lymphoblastic leukemia حسب Esther L. Monsees, Udo zur Stadt, Julia Strauss, Sabrina Schuster, Nadja Kleist, Richard T. Hauch, Michael Spohn, Gerrit Wolters-Eisfeld, Martin A. Horstmann, Gabriele Escherich, Lena Behrmann

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Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I_bk,Ca) حسب András Horváth, Torsten Christ, Jussi T. Koivumäki, Maksymilian Prondzynski, Antonia T. L. Zech, Michael Spohn, Umber Saleem, Ingra Mannhardt, Bärbel Ulmer, Evaldas Girdauskas, Christian Meyer, Arne Hansen, Thomas Eschenhagen, Marc D. Lemoine

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Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcom... حسب Gabriele Escherich, Udo zur Stadt, Arndt Borkhardt, Dagmar Dilloo, Jörg Faber, Tobias Feuchtinger, Thomas Imschweiler, Norbert Jorch, Arnulf Pekrun, Irene Schmid, Franziska Schramm, Michael Spohn, Martin Zimmermann, Martin A Horstmann

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MVA-based SARS-CoV-2 vaccine candidates encoding different spike protein conformations induce distinct early transcriptional responses which may impact subsequent adaptive immunity حسب Ilka Grewe, Ilka Grewe, Ilka Grewe, Ilka Grewe, Monika Friedrich, Monika Friedrich, Monika Friedrich, Marie-Louise Dieck, Marie-Louise Dieck, Marie-Louise Dieck, Michael Spohn, Michael Spohn, Michael Spohn, My Linh Ly, My Linh Ly, My Linh Ly, Verena Krähling, Verena Krähling, Leonie Mayer, Leonie Mayer, Leonie Mayer, Sibylle C. Mellinghoff, Sibylle C. Mellinghoff, Sibylle C. Mellinghoff, Monika Rottstegge, Monika Rottstegge, Monika Rottstegge, Rebekka Kraemer, Asisa Volz, Asisa Volz, Stephan Becker, Stephan Becker, Anahita Fathi, Anahita Fathi, Anahita Fathi, Anahita Fathi, Christine Dahlke, Christine Dahlke, Christine Dahlke, Leonie M. Weskamm, Leonie M. Weskamm, Leonie M. Weskamm, Marylyn M. Addo, Marylyn M. Addo, Marylyn M. Addo

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High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms. حسب Manja Czech-Sioli, Thomas Günther, Marlin Therre, Michael Spohn, Daniela Indenbirken, Juliane Theiss, Sabine Riethdorf, Minyue Qi, Malik Alawi, Corinna Wülbeck, Irene Fernandez-Cuesta, Franziska Esmek, Jürgen C Becker, Adam Grundhoff, Nicole Fischer

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The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration حسب Melanie Schoof, Michael Launspach, Dörthe Holdhof, Lynhda Nguyen, Verena Engel, Severin Filser, Finn Peters, Jana Immenschuh, Malte Hellwig, Judith Niesen, Volker Mall, Birgit Ertl-Wagner, Christian Hagel, Michael Spohn, Beat Lutz, Jan Sedlacik, Daniela Indenbirken, Daniel J. Merk, Ulrich Schüller

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy حسب Maksymilian Prondzynski, Marc D Lemoine, Antonia TL Zech, András Horváth, Vittoria Di Mauro, Jussi T Koivumäki, Nico Kresin, Josefine Busch, Tobias Krause, Elisabeth Krämer, Saskia Schlossarek, Michael Spohn, Felix W Friedrich, Julia Münch, Sandra D Laufer, Charles Redwood, Alexander E Volk, Arne Hansen, Giulia Mearini, Daniele Catalucci, Christian Meyer, Torsten Christ, Monica Patten, Thomas Eschenhagen, Lucie Carrier

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy حسب Maksymilian Prondzynski, Marc D Lemoine, Antonia TL Zech, András Horváth, Vittoria Di Mauro, Jussi T Koivumäki, Nico Kresin, Josefine Busch, Tobias Krause, Elisabeth Krämer, Saskia Schlossarek, Michael Spohn, Felix W Friedrich, Julia Münch, Sandra D Laufer, Charles Redwood, Alexander E Volk, Arne Hansen, Giulia Mearini, Daniele Catalucci, Christian Meyer, Torsten Christ, Monica Patten, Thomas Eschenhagen, Lucie Carrier

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Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors حسب Daniel J. Merk, Foteini Tsiami, Sophie Hirsch, Bianca Walter, Lara A. Haeusser, Jens D. Maile, Aaron Stahl, Mohamed A. Jarboui, Anna Lechado-Terradas, Franziska Klose, Sepideh Babaei, Jakob Admard, Nicolas Casadei, Cristiana Roggia, Michael Spohn, Jens Schittenhelm, Stephan Singer, Ulrich Schüller, Federica Piccioni, Nicole S. Persky, Manfred Claassen, Marcos Tatagiba, Philipp J. Kahle, David E. Root, Markus Templin, Ghazaleh Tabatabai

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Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells حسب Lisa-Marie Rieckmann, Michael Spohn, Lisa Ruff, David Agorku, Lisa Becker, Alina Borchers, Jenny Krause, Roisin O’Reilly, Jurek Hille, Janna-Lisa Velthaus-Rusik, Niklas Beumer, Armin Günther, Lena Willnow, Charles D. Imbusch, Peter Iglauer, Ronald Simon, Sören Franzenburg, Hauke Winter, Michael Thomas, Carsten Bokemeyer, Nicola Gagliani, Christian F. Krebs, Martin Sprick, Olaf Hardt, Sabine Riethdorf, Andreas Trumpp, Nikolas H. Stoecklein, Sven Peine, Philipp Rosenstiel, Klaus Pantel, Sonja Loges, Melanie Janning

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Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2 حسب Shuyong Zhu, Nancy Stanslowsky, Jorge Fernández-Trillo, Tamrat M. Mamo, Pengfei Yu, Norman Kalmbach, Birgit Ritter, Reto Eggenschwiler, Werner J.D. Ouwendijk, David Mzinza, Likai Tan, Andreas Leffler, Michael Spohn, Richard J.P. Brown, Kai A. Kropp, Volkhard Kaever, Teng-Cheong Ha, Pratibha Narayanan, Adam Grundhoff, Reinhold Förster, Axel Schambach, Georges M.G.M. Verjans, Manuela Schmidt, Andreas Kispert, Tobias Cantz, Ana Gomis, Florian Wegner, Abel Viejo-Borbolla

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