Bilaketaren emaitzak - Matthew P. Goetz

Evaluation of the androgen receptor in patients with ERα-positive early breast cancer treated with adjuvant tamoxifen ± fluoxymesterone nork James N. Ingle, Vera J. Suman, Malvika H. Solanki, Marie R. Passow, Jordan D. Campbell, Liewei Wang, Matthew P. Goetz

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Abemaciclib as initial therapy for advanced breast cancer: MONARCH 3 updated results in prognostic subgroups nork Stephen Johnston, Joyce O’Shaughnessy, Miguel Martin, Jens Huober, Masakazu Toi, Joohyuk Sohn, Valérie A. M. André, Holly R. Martin, Molly C. Hardebeck, Matthew P. Goetz

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Abemaciclib in combination with therapies for patients with metastatic breast cancer: a phase 1b study nork Sara M. Tolaney, Komal Jhaveri, Teresa Helsten, Shannon L. Puhalla, Alison Conlin, E. Claire Dees, Muralidhar Beeram, Sonya C. Chapman, Andrew Lithio, Lacey M. Litchfield, Matthew P. Goetz

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Impact of dose reductions on adjuvant abemaciclib efficacy for patients with high-risk early breast cancer: analyses from the monarchE study nork Matthew P. Goetz, Irfan Cicin, Laura Testa, Sara M. Tolaney, Jens Huober, Valentina Guarneri, Stephen R. D. Johnston, Miguel Martin, Priya Rastogi, Nadia Harbeck, Ashwin Shahir, Ran Wei, Valérie André, Hope S. Rugo, Joyce O’Shaughnessy

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Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX) nork Yongxian Zhuang, Jordan M. Grainger, Peter T. Vedell, Jia Yu, Ann M. Moyer, Huanyao Gao, Xiao-Yang Fan, Sisi Qin, Duan Liu, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Richard M. Weinshilboum, Liewei Wang

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Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes nork Duan Liu, Ming-Fen Ho, Daniel J. Schaid, Steven E. Scherer, Krishna Kalari, Mohan Liu, Joanna Biernacka, Vivien Yee, Jared Evans, Erin Carlson, Matthew P. Goetz, Michiaki Kubo, D. Lawrence Wickerham, Liewei Wang, James N. Ingle, Richard M. Weinshilboum

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Identification of a Notch transcriptomic signature for breast cancer nork Eike-Benjamin Braune, Felix Geist, Xiaojia Tang, Krishna Kalari, Judy Boughey, Liewei Wang, Roberto A. Leon-Ferre, Antonino B. D’Assoro, James N. Ingle, Matthew P. Goetz, Julian Kreis, Kang Wang, Theodoros Foukakis, Anita Seshire, Dirk Wienke, Urban Lendahl

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Patient-specific signaling signatures predict optimal therapeutic combinations for triple negative breast cancer nork Heba Alkhatib, Jason Conage-Pough, Sangita Roy Chowdhury, Denen Shian, Deema Zaid, Ariel M. Rubinstein, Amir Sonnenblick, Tamar Peretz-Yablonsky, Avital Granit, Einat Carmon, Ishwar N. Kohale, Judy C. Boughey, Matthew P. Goetz, Liewei Wang, Forest M. White, Nataly Kravchenko-Balasha

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Automated mitotic spindle hotspot counts are highly associated with clinical outcomes in systemically untreated early-stage triple-negative breast cancer nork Roberto A. Leon-Ferre, Jodi M. Carter, David Zahrieh, Jason P. Sinnwell, Roberto Salgado, Vera J. Suman, David W. Hillman, Judy C. Boughey, Krishna R. Kalari, Fergus J. Couch, James N. Ingle, Maschenka Balkenhol, Francesco Ciompi, Jeroen van der Laak, Matthew P. Goetz

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Efficacy and safety results by menopausal status in monarchE: adjuvant abemaciclib combined with endocrine therapy in patients with HR+, HER2−, node-positive, high-risk early breas... nork Shani Paluch-Shimon, Patrick Neven, Jens Huober, Irfan Cicin, Matthew P. Goetz, Chikako Shimizu, Chiun-Sheng Huang, Hans Joachim Lueck, Jane Beith, Eriko Tokunaga, Jessica Reyes Contreras, Rosane Oliveira de Sant’Ana, Ran Wei, Ashwin Shahir, Sarah C. Nabinger, Tammy Forrester, Stephen R. D. Johnston, Nadia Harbeck

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Molecular basis of allosteric regulation and pharmaceutical targeting of protein kinase Cβ nork Anh T. Q. Cong, Taylor L. Witter, Elizabeth S. Bruinsma, Sayantani Sarkar Bhattacharya, Swaathi Jayaraman, Samuel R. Wyatt, Jasper K. Solverson, Maria B. Dugan, Jasmina Paluncic, Mary J. Kuffel, Julia R. Alvey, Huy V. Huynh, Xinyan Wu, Alan P. Fields, Akhilesh Pandey, John R. Hawse, Matthew P. Goetz, Matthew J. Schellenberg

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Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer nork Swaathi Jayaraman, Xinyan Wu, Krishna R. Kalari, Xiaojia Tang, Mary J. Kuffel, Elizabeth S. Bruinsma, Shahrzad Jalali, Kevin L. Peterson, Cristina Correia, Rachel A. Kudgus, Scott H. Kaufmann, Santosh Renuse, James N. Ingle, Joel M. Reid, Matthew M. Ames, Alan P. Fields, Matthew J. Schellenberg, John R. Hawse, Akhilesh Pandey, Matthew P. Goetz

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CHFR expression and sensitivity of breast cancer cells to antimitotic agents in vitro and in the I-SPY trial nork Andrea E. Wahner Hendrickson, Karen S. Flatten, Taylor M. Weiskittel, Annapoorna Venkatachalam, Annabella R. Strathman, Olivia K. Rossman, X. Wei Meng, Paula A. Schneider, Kevin L. Peterson, Cristina Correia, Olivia J. Anderson, Saloni Singh, Fergus J. Couch, Laura J. Esserman, Nola M. Hylton, Natsuko Onishi, Angela M. DeMichele, Junjie Chen, Hu Li, James N. Ingle, Matthew P. Goetz, Scott H. Kaufmann

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Pre-treatment peripheral blood immunophenotyping and response to neoadjuvant chemotherapy in operable breast cancer nork Roberto A. Leon-Ferre, Kaitlyn R. Whitaker, Vera J. Suman, Tanya Hoskin, Karthik V. Giridhar, Raymond M. Moore, Ahmad Al-Jarrad, Sarah A. McLaughlin, Donald W. Northfelt, Katie N. Hunt, Amy Lynn Conners, Ann Moyer, Jodi M. Carter, Krishna Kalari, Richard Weinshilboum, Liewei Wang, James N. Ingle, Keith L. Knutson, Stephen M. Ansell, Judy C. Boughey, Matthew P. Goetz, Jose C. Villasboas

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Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer nork Kirsten G. M. Aspros, Jodi M. Carter, Tanya L. Hoskin, Vera J. Suman, Malayannan Subramaniam, Michael J. Emch, Zhenqing Ye, Zhifu Sun, Jason P. Sinnwell, Kevin J. Thompson, Xiaojia Tang, Esther P. B. Rodman, Xiyin Wang, Adam W. Nelson, Igor Chernukhin, Feda H. Hamdan, Elizabeth S. Bruinsma, Jason S. Carroll, Martin E. Fernandez-Zapico, Steven A. Johnsen, Krishna R. Kalari, Haojie Huang, Roberto A. Leon-Ferre, Fergus J. Couch, James N. Ingle, Matthew P. Goetz, John R. Hawse

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A pooled analysis evaluating prognostic significance of Residual Cancer Burden in invasive lobular breast cancer nork Rita A. Mukhtar, Soumya Gottipati, Christina Yau, Sara López-Tarruella, Helena Earl, Larry Hayward, Louise Hiller, Marie Osdoit, Marieke van der Noordaa, Diane de Croze, Anne-Sophie Hamy, Marick Laé, Fabien Reyal, Gabe S. Sonke, Tessa G. Steenbruggen, Maartje van Seijen, Jelle Wesseling, Miguel Martín, Maria del Monte-Millán, Judy C. Boughey, Matthew P. Goetz, Tanya Hoskin, Vicente Valero, Stephen B. Edge, Jean E. Abraham, John M. S. Bartlett, Carlos Caldas, Janet Dunn, Elena Provenzano, Stephen-John Sammut, Jeremy S. Thomas, Ashley Graham, Peter Hall, Lorna Mackintosh, Fang Fan, Andrew K. Godwin, Kelsey Schwensen, Priyanka Sharma, Angela M. DeMichele, Kimberly Cole, Lajos Pusztai, Mi-Ok Kim, Laura J van ’t Veer, David Cameron, Laura J. Esserman, W. Fraser Symmans

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Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer nork Reiner Hoppe, Stefan Winter, Wing-Yee Lo, Kyriaki Michailidou, Manjeet K. Bolla, Renske Keeman, Qin Wang, Joe Dennis, Michael Lush, Krishna R. Kalari, Matthew P. Goetz, Liewei Wang, Junmei Cairns, Richard Weinshilboum, Lois Shepherd, Bingshu E. Chen, Lothar Häberle, Matthias Ruebner, Matthias W. Beckmann, Wei He, Nicole L. Larson, Sebastian M. Armasu, Werner Schroth, Balram Chowbay, Chiea Chuen Khor, Mustapha Abubakar, Antonis C. Antoniou, Thomas Brüning, Jose E. Castelao, Jenny Chang-Claude, NBCS Collaborators, Thilo Dörk, Diana M. Eccles, Jonine D. Figueroa, Manuela Gago-Dominguez, José A. García-Sáenz, Melanie Gündert, Carolin C. Hack, Ute Hamann, Sileny Han, Maartje J. Hooning, Hanna Huebner, ABCTB Investigators, Esther M. John, Yon-Dschun Ko, Vessela N. Kristensen, Sabine Linn, Sara Margolin, Dimitrios Mavroudis, Heli Nevanlinna, Patrick Neven, Nadia Obi, Tjoung-Won Park-Simon, Katri Pylkäs, Muhammad U. Rashid, Atocha Romero, Emmanouil Saloustros, Elinor J. Sawyer, William J. Tapper, Ian Tomlinson, Camilla Wendt, Robert Winqvist, Alison M. Dunning, Jacques Simard, Per Hall, Paul D. P. Pharoah, Matthias Schwab, Fergus J. Couch, Kamila Czene, Peter A. Fasching, Douglas F. Easton, Marjanka K. Schmidt, James N. Ingle, Hiltrud Brauch

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