Ohcanbohtosat - Mathieu J. F. Crupi

Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus Dahkki Zaid Taha, Zaid Taha, Mathieu J.F. Crupi, Mathieu J.F. Crupi, Nouf Alluqmani, Nouf Alluqmani, Faiha Fareez, Kristy Ng, Judy Sobh, Emily Lee, Andrew Chen, Max Thomson, Marcus M. Spinelli, Carolina S. Ilkow, Carolina S. Ilkow, John C. Bell, John C. Bell, Rozanne Arulanandam, Jean-Simon Diallo, Jean-Simon Diallo

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Enhanced susceptibility of cancer cells to oncolytic rhabdo-virotherapy by expression of Nodamura virus protein B2 as a suppressor of RNA interference Dahkki Donald Bastin, Amelia S. Aitken, Adrian Pelin, Larissa A. Pikor, Mathieu J. F. Crupi, Michael S. Huh, Marie-Claude Bourgeois-Daigneault, John C. Bell, Carolina S. Ilkow

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A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion Dahkki Taha Azad, Reza Rezaei, Ragunath Singaravelu, Taylor R. Jamieson, Mathieu J. F. Crupi, Abera Surendran, Joanna Poutou, Parisa Taklifi, Juthaporn Cowan, Donald William Cameron, Carolina S. Ilkow

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High throughput screen identifies lysosomal acid phosphatase 2 (ACP2) to regulate IFN-1 responses to potentiate oncolytic VSV∆51 activity Dahkki Boaz Wong, Rayanna Birtch, Anabel Bergeron, Kristy Ng, Glib Maznyi, Marcus Spinelli, Andrew Chen, Anne Landry, Mathieu J. F. Crupi, Rozanne Arulanandam, Carolina S. Ilkow, Jean-Simon Diallo

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Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic Dahkki Taha Azad, Helena J. Janse van Rensburg, Jessica Morgan, Reza Rezaei, Mathieu J. F. Crupi, Rui Chen, Mina Ghahremani, Monire Jamalkhah, Nicole Forbes, Carolina Ilkow, John C. Bell

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Oncolytic vaccinia virus encoding constitutively active EPAC remodels the tumor microenvironment to enhance therapeutic efficacy with chemotherapy and surgery Dahkki Siddharth Singh, Xiaohong He, Julia Thomas, Sydney Vallati, Julia Petryk, Bradley Austin, Stephen Boulton, Carolina Ilkow, Bailey Organ, Reza Rezaei, Rida Gill, Quanshen Guo, Jaahnavi Dave, Christiano Tanese De Souza, Amy Gingrich, Mathieu J F Crupi, Ragunath Singaravelu, John C Bell

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Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy Dahkki Nikolas T. Martin, Mathieu J. F. Crupi, Zaid Taha, Joanna Poutou, Jack T. Whelan, Sydney Vallati, Julia Petryk, Ricardo Marius, Bradley Austin, Taha Azad, Mason Boulanger, Tamara Burgess, Ilson Sanders, Camille Victoor, Bryan C. Dickinson, Jean-Simon Diallo, Carolina S. Ilkow, John C. Bell

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Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase Dahkki Laura A. Orofiamma, Ralph Christian Delos Santos, Ayshin Mehrabi, Nikol Leshchyshyn, Geoffrey G. Hesketh, Sadia Rahmani, Aesha Patel, Farnaz Fekri, Rehman Ata, Colin D.H. Ratcliffe, Mathieu J.F. Crupi, Lois Mulligan, Morag Park, Anne-Claude Gingras, Costin N. Antonescu

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A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection Dahkki Stephen Boulton, Joanna Poutou, Rida Gill, Nouf Alluqmani, Xiaohong He, Ragunath Singaravelu, Mathieu J.F. Crupi, Julia Petryk, Bradley Austin, Leonard Angka, Zaid Taha, Iris Teo, Siddarth Singh, Rameen Jamil, Ricardo Marius, Nikolas Martin, Taylor Jamieson, Taha Azad, Jean-Simon Diallo, Carolina S. Ilkow, John C. Bell

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Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization Dahkki Taha Azad, Ragunath Singaravelu, Mathieu J.F. Crupi, Taylor Jamieson, Jaahnavi Dave, Emily E.F. Brown, Reza Rezaei, Zaid Taha, Stephen Boulton, Nikolas T. Martin, Abera Surendran, Joanna Poutou, Mina Ghahremani, Kazem Nouri, Jack T. Whelan, Jessie Duong, Sarah Tucker, Jean-Simon Diallo, John C. Bell, Carolina S. Ilkow

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Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment Dahkki Abera Surendran, Abera Surendran, Monire Jamalkhah, Monire Jamalkhah, Joanna Poutou, Rayanna Birtch, Rayanna Birtch, Christine Lawson, Jaahnavi Dave, Jaahnavi Dave, Mathieu J. F. Crupi, Mathieu J. F. Crupi, Justin Mayer, Victoria Taylor, Julia Petryk, Christiano Tanese de Souza, Neil Moodie, Jacob Lecompte Billingsley, Bradley Austin, Nicole Cormack, Natalie Blamey, Reza Rezaei, Reza Rezaei, Curtis W. McCloskey, Curtis W. McCloskey, Emily E. F. Fekete, Emily E. F. Fekete, Harsimrat K. Birdi, Harsimrat K. Birdi, Serge Neault, Serge Neault, Taylor R. Jamieson, Taylor R. Jamieson, Brenna Wylie, Sarah Tucker, Taha Azad, Taha Azad, Barbara Vanderhyden, Barbara Vanderhyden, Lee-Hwa Tai, John C. Bell, John C. Bell, Carolina S. Ilkow, Carolina S. Ilkow

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CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX Dahkki Jack T. Whelan, Jack T. Whelan, Ragunath Singaravelu, Ragunath Singaravelu, Ragunath Singaravelu, Fuan Wang, Fuan Wang, Adrian Pelin, Adrian Pelin, Levi A. Tamming, Levi A. Tamming, Giuseppe Pugliese, Nikolas T. Martin, Nikolas T. Martin, Mathieu J. F. Crupi, Mathieu J. F. Crupi, Julia Petryk, Bradley Austin, Xiaohong He, Ricardo Marius, Ricardo Marius, Jessie Duong, Jessie Duong, Carter Jones, Emily E. F. Fekete, Emily E. F. Fekete, Nouf Alluqmani, Nouf Alluqmani, Andrew Chen, Stephen Boulton, Stephen Boulton, Michael S. Huh, Matt Y. Tang, Zaid Taha, Zaid Taha, Elena Scut, Elena Scut, Jean-Simon Diallo, Jean-Simon Diallo, Taha Azad, Taha Azad, Brian D. Lichty, Brian D. Lichty, Carolina S. Ilkow, Carolina S. Ilkow, John C. Bell, John C. Bell

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Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer Dahkki Mathieu J. F. Crupi, Mathieu J. F. Crupi, Zaid Taha, Zaid Taha, Thijs J. A. Janssen, Julia Petryk, Stephen Boulton, Stephen Boulton, Nouf Alluqmani, Nouf Alluqmani, Anna Jirovec, Anna Jirovec, Omar Kassas, Sarwat T. Khan, Sydney Vallati, Sydney Vallati, Emily Lee, Ben Zhen Huang, Michael Huh, Michael Huh, Larissa Pikor, Larissa Pikor, Larissa Pikor, Xiaohong He, Ricardo Marius, Bradley Austin, Jessie Duong, Jessie Duong, Jessie Duong, Adrian Pelin, Adrian Pelin, Adrian Pelin, Serge Neault, Serge Neault, Taha Azad, Taha Azad, Caroline J. Breitbach, David F. Stojdl, Michael F. Burgess, Scott McComb, Scott McComb, Rebecca Auer, Rebecca Auer, Jean-Simon Diallo, Jean-Simon Diallo, Carolina S. Ilkow, Carolina S. Ilkow, John Cameron Bell, John Cameron Bell

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Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies Dahkki Taha Azad, Reza Rezaei, Ragunath Singaravelu, Adrian Pelin, Stephen Boulton, Julia Petryk, Kemal Alper Onsu, Nikolas T. Martin, Victoria Hoskin, Mina Ghahremani, Marie Marotel, Ricardo Marius, Xiaohong He, Mathieu J. F. Crupi, Huy-Dung Hoang, Abolfazl Nik-Akhtar, Mahsa Ahmadi, Nika Kooshki Zamani, Ashkan Golshani, Tommy Alain, Peter Greer, Michele Ardolino, Bryan C. Dickinson, Lee-Hwa Tai, Carolina S. Ilkow, John C. Bell

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Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy Dahkki Marie-Eve Wedge, Victoria A. Jennings, Mathieu J. F. Crupi, Joanna Poutou, Taylor Jamieson, Adrian Pelin, Giuseppe Pugliese, Christiano Tanese de Souza, Julia Petryk, Brian J. Laight, Meaghan Boileau, Zaid Taha, Nouf Alluqmani, Hayley E. McKay, Larissa Pikor, Sarwat Tahsin Khan, Taha Azad, Reza Rezaei, Bradley Austin, Xiaohong He, David Mansfield, Elaine Rose, Emily E. F. Brown, Natalie Crawford, Almohanad Alkayyal, Abera Surendran, Ragunath Singaravelu, Dominic G. Roy, Gemma Migneco, Benjamin McSweeney, Mary Lynn Cottee, Egon J. Jacobus, Brian A. Keller, Takafumi N. Yamaguchi, Paul C. Boutros, Michele Geoffrion, Katey J. Rayner, Avijit Chatterjee, Rebecca C. Auer, Jean-Simon Diallo, Derrick Gibbings, Benjamin R. tenOever, Alan Melcher, John C. Bell, Carolina S. Ilkow

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