Glial phagocytic clearance in Parkinson’s disease

Por Marie-Eve Tremblay, Mark R. Cookson, Laura Civiero
Publicado em 2019-04-01

Directing LRRK2 to membranes of the endolysosomal pathway triggers RAB phosphorylation and JIP4 recruitment

Por Jillian H. Kluss, Luis Bonet-Ponce, Patrick A. Lewis, Mark R. Cookson
Publicado em 2022-08-01

Hexokinases link DJ-1 to the PINK1/parkin pathway

Por David N. Hauser, Adamantios Mamais, Melissa M. Conti, Christopher T. Primiani, Ravindran Kumaran, Allissa A. Dillman, Rebekah G. Langston, Alexandra Beilina, Joseph H. Garcia, Alberto Diaz-Ruiz, Michel Bernier, Fabienne C. Fiesel, Xu Hou, Wolfdieter Springer, Yan Li, Rafael de Cabo, Mark R. Cookson
Publicado em 2017-09-01

Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.

Por Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson
Publicado em 2021-12-01

Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.

Por Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Kirsten Harvey, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson
Publicado em 2022-05-01

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2

Por Laura Civiero, Susanna Cogo, Susanna Cogo, Anneleen Kiekens, Claudia Morganti, Isabella Tessari, Evy Lobbestael, Veerle Baekelandt, Jean-Marc Taymans, Jean-Marc Taymans, Marie-Christine Chartier-Harlin, Marie-Christine Chartier-Harlin, Cinzia Franchin, Cinzia Franchin, Giorgio Arrigoni, Giorgio Arrigoni, Patrick A. Lewis, Giovanni Piccoli, Luigi Bubacco, Mark R. Cookson, Paolo Pinton, Elisa Greggio
Publicado em 2017-12-01

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

Por Jesús Madero-Pérez, Elena Fdez, Belén Fernández, Antonio J. Lara Ordóñez, Marian Blanca Ramírez, Patricia Gómez-Suaga, Dieter Waschbüsch, Evy Lobbestael, Veerle Baekelandt, Angus C. Nairn, Javier Ruiz-Martínez, Ana Aiastui, Adolfo López de Munain, Pawel Lis, Thomas Comptdaer, Jean-Marc Taymans, Marie-Christine Chartier-Harlin, Alexandria Beilina, Adriano Gonnelli, Mark R. Cookson, Elisa Greggio, Sabine Hilfiker
Publicado em 2018-01-01