uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

Por Pavón, Miguel Angel, Arroyo-Solera, Irene, Céspedes, Maria Virtudes, Casanova, Isolda, León, Xavier, Mangues, Ramón
Publicado no Oncotarget (2016)

Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors

Por Mira, Alessia, Morello, Virginia, Céspedes, Maria Virtudes, Perera, Timothy, Comoglio, Paolo M., Mangues, Ramon, Michieli, Paolo
Publicado no Oncotarget (2017)

A novel orally available inhibitor of focal adhesion signaling increases survival in a xenograft model of diffuse large B-cell lymphoma with central nervous system involvement

Por Bosch, Rosa, Moreno, María José, Dieguez-Gonzalez, Rebeca, Céspedes, María Virtudes, Gallardo, Alberto, Trias, Manuel, Grañena, Albert, Sierra, Jorge, Casanova, Isolda, Mangues, Ramon
Publicado em 2013

Neural plasticity of the uterus: New targets for endometrial cancer?

Por Pia Español, Rocio Luna, Cristina Soler, Pablo Caruana, Amanda Altés-Arranz, Francisco Rodríguez, Oriol Porta, Olga Sanchez, Elisa Llurba, Ramón Rovira, María Virtudes Céspedes
Publicado em 2022-04-01

Site-Dependent E-Cadherin Cleavage and Nuclear Translocation in a Metastatic Colorectal Cancer Model

Por Céspedes, María Virtudes, Larriba, María Jesús, Pavón, Miguel Angel, Álamo, Patricia, Casanova, Isolda, Parreño, Matilde, Feliu, Anna, Sancho, Francesc Josep, Muñoz, Alberto, Mangues, Ramón
Publicado em 2010

Intracellular CXCR4(+) cell targeting with T22-empowered protein-only nanoparticles

Por Unzueta, Ugutz, Céspedes, María Virtudes, Ferrer-Miralles, Neus, Casanova, Isolda, Cedano, Juan, Corchero, José Luis, Domingo-Espín, Joan, Villaverde, Antonio, Mangues, Ramón, Vázquez, Esther
Publicado em 2012

Orthotopic Microinjection of Human Colon Cancer Cells in Nude Mice Induces Tumor Foci in All Clinically Relevant Metastatic Sites

Por Céspedes, María Virtudes, Espina, Carolina, García-Cabezas, Miguel Angel, Trias, Manuel, Boluda, Alicia, Gómez del Pulgar, María Teresa, Sancho, Francesc Josep, Nistal, Manuel, Lacal, Juan Carlos, Mangues, Ramon
Publicado em 2007

A Critical Role for Rac1 in Tumor Progression of Human Colorectal Adenocarcinoma Cells

Por Espina, Carolina, Céspedes, María Virtudes, García-Cabezas, Miguel Angel, del Pulgar, María Teresa Gómez, Boluda, Alicia, Oroz, Lourdes García, Cejas, Paloma, Nistal, Manuel, Mangues, Ramón, Lacal, Juan Carlos
Publicado em 2008

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models

Por María Virtudes Céspedes, María José Guillén, Pedro Pablo López-Casas, Francesca Sarno, Alberto Gallardo, Patricia Álamo, Carmen Cuevas, Manuel Hidalgo, Carlos María Galmarini, Paola Allavena, Pablo Avilés, Ramón Mangues
Publicado em 2016-12-01

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models

Por Céspedes, María Virtudes, Guillén, María José, López-Casas, Pedro Pablo, Sarno, Francesca, Gallardo, Alberto, Álamo, Patricia, Cuevas, Carmen, Hidalgo, Manuel, Galmarini, Carlos María, Allavena, Paola, Avilés, Pablo, Mangues, Ramón
Publicado no Dis Model Mech (2016)

A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models

Por Falgàs, Aïda, Pallarès, Victor, Unzueta, Ugutz, Céspedes, María Virtudes, Arroyo-Solera, Irene, Moreno, María José, Sierra, Jorge, Gallardo, Alberto, Mangues, María Antonia, Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon, Casanova, Isolda
Publicado no Haematologica (2020)

GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases

Por Rita Sala, Elisa Rioja-Blanco, Naroa Serna, Laura Sánchez-García, Patricia Álamo, Lorena Alba-Castellón, Isolda Casanova, Antonio López-Pousa, Ugutz Unzueta, María Virtudes Céspedes, Esther Vázquez, Antonio Villaverde, Ramon Mangues
Publicado em 2022-12-01

Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli

Por Rueda, Fabián, Céspedes, María Virtudes, Sánchez-Chardi, Alejandro, Seras-Franzoso, Joaquin, Pesarrodona, Mireia, Ferrer-Miralles, Neus, Vázquez, Esther, Rinas, Ursula, Unzueta, Ugutz, Mamat, Uwe, Mangues, Ramón, García-Fruitós, Elena, Villaverde, Antonio
Publicado no Microb Cell Fact (2016)

Selective depletion of metastatic stem cells as therapy for human colorectal cancer

Por Céspedes, María Virtudes, Unzueta, Ugutz, Aviñó, Anna, Gallardo, Alberto, Álamo, Patricia, Sala, Rita, Sánchez‐Chardi, Alejandro, Casanova, Isolda, Mangues, María Antònia, Lopez‐Pousa, Antonio, Eritja, Ramón, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramón
Publicado no EMBO Mol Med (2018)

Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients

Por Pavón, Miguel Angel, Arroyo-Solera, Irene, Téllez-Gabriel, Marta, León, Xavier, Virós, David, López, Montserrat, Gallardo, Alberto, Céspedes, Maria Virtudes, Casanova, Isolda, López-Pousa, Antonio, Mangues, Maria Antonia, Quer, Miquel, Barnadas, Agustí, Mangues, Ramón
Publicado no Oncotarget (2015)

CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis

Por Moreno, María José, Gallardo, Alberto, Novelli, Silvana, Mozos, Ana, Aragó, Marc, Pavón, Miguel Ángel, Céspedes, María Virtudes, Pallarès, Víctor, Falgàs, Aïda, Alcoceba, Miguel, Blanco, Oscar, Gonzalez-Díaz, Marcos, Sierra, Jorge, Mangues, Ramon, Casanova, Isolda
Publicado no PLoS One (2018)

NEDD9, an independent good prognostic factor in intermediate-risk acute myeloid leukemia patients

Por Pallarès, Victor, Hoyos, Montserrat, Chillón, M. Carmen, Barragán, Eva, Conde, M. Isabel Prieto, Llop, Marta, Céspedes, María Virtudes, Nomdedeu, Josep F., Brunet, Salut, Sanz, Miguel Ángel, González-Díaz, Marcos, Sierra, Jorge, Casanova, Isolda, Mangues, Ramon
Publicado no Oncotarget (2017)

Bacterial mimetics of endocrine secretory granules as immobilized in vivo depots for functional protein drugs

Por Céspedes, María Virtudes, Fernández, Yolanda, Unzueta, Ugutz, Mendoza, Rosa, Seras-Franzoso, Joaquin, Sánchez-Chardi, Alejando, Álamo, Patricia, Toledo-Rubio, Verónica, Ferrer-Miralles, Neus, Vázquez, Esther, Schwartz, Simó, Abasolo, Ibane, Corchero, José Luis, Mangues, Ramon, Villaverde, Antonio
Publicado no Sci Rep (2016)

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease

Por Gomez‐Arboledas, Angela, Davila, Jose C., Sanchez‐Mejias, Elisabeth, Navarro, Victoria, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Sanchez‐Mico, Maria Virtudes, Trujillo‐Estrada, Laura, Fernandez‐Valenzuela, Juan Jose, Vizuete, Marisa, Comella, Joan X., Galea, Elena, Vitorica, Javier, Gutierrez, Antonia
Publicado no Glia (2017)

Focal Adhesion Genes Refine the Intermediate-Risk Cytogenetic Classification of Acute Myeloid Leukemia

Por Pallarès, Victor, Hoyos, Montserrat, Chillón, M. Carmen, Barragán, Eva, Prieto Conde, M. Isabel, Llop, Marta, Falgàs, Aïda, Céspedes, María Virtudes, Montesinos, Pau, Nomdedeu, Josep F., Brunet, Salut, Sanz, Miguel Ángel, González-Díaz, Marcos, Sierra, Jorge, Mangues, Ramon, Casanova, Isolda
Publicado no Cancers (Basel) (2018)