Rezultaty - Luke A. Gilbert

A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy od Christopher Yogodzinski, Abolfazl Arab, Justin R. Pritchard, Hani Goodarzi, Luke A. Gilbert

Dokumenty pełnotekstowe

Cellular response to small molecules that selectively stall protein synthesis by the ribosome. od Nadège Liaud, Max A Horlbeck, Luke A Gilbert, Ketrin Gjoni, Jonathan S Weissman, Jamie H D Cate

Dokumenty pełnotekstowe

Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis od Becky Xu Hua Fu, Albert Xu, Hua Li, Daniel E. Johnson, Jennifer R. Grandis, Luke A. Gilbert

Dokumenty pełnotekstowe

Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity od Duy P. Nguyen, Yuichiro Miyaoka, Luke A. Gilbert, Steven J. Mayerl, Brian H. Lee, Jonathan S. Weissman, Bruce R. Conklin, James A. Wells

Dokumenty pełnotekstowe

Nucleosomes impede Cas9 access to DNA in vivo and in vitro od Max A Horlbeck, Lea B Witkowsky, Benjamin Guglielmi, Joseph M Replogle, Luke A Gilbert, Jacqueline E Villalta, Sharon E Torigoe, Robert Tjian, Jonathan S Weissman

Dokumenty pełnotekstowe

Versatile protein tagging in cells with split fluorescent protein od Daichi Kamiyama, Sayaka Sekine, Benjamin Barsi-Rhyne, Jeffrey Hu, Baohui Chen, Luke A. Gilbert, Hiroaki Ishikawa, Manuel D. Leonetti, Wallace F. Marshall, Jonathan S. Weissman, Bo Huang

Dokumenty pełnotekstowe

Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome od Duygu Kuzuoglu-Ozturk, Zhiqiang Hu, Martina Rama, Emily Devericks, Jacob Weiss, Gary G. Chiang, Stephen T. Worland, Steven E. Brenner, Hani Goodarzi, Luke A. Gilbert, Davide Ruggero

Dokumenty pełnotekstowe

Highly efficient generation of isogenic pluripotent stem cell models using prime editing od Hanqin Li, Oriol Busquets, Yogendra Verma, Khaja Mohieddin Syed, Nitzan Kutnowski, Gabriella R Pangilinan, Luke A Gilbert, Helen S Bateup, Donald C Rio, Dirk Hockemeyer, Frank Soldner

Dokumenty pełnotekstowe

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation od Max A Horlbeck, Luke A Gilbert, Jacqueline E Villalta, Britt Adamson, Ryan A Pak, Yuwen Chen, Alexander P Fields, Chong Yon Park, Jacob E Corn, Martin Kampmann, Jonathan S Weissman

Dokumenty pełnotekstowe

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure. od Bryce A Mendelsohn, Neal K Bennett, Maxwell A Darch, Katharine Yu, Mai K Nguyen, Daniela Pucciarelli, Maxine Nelson, Max A Horlbeck, Luke A Gilbert, William Hyun, Martin Kampmann, Jean L Nakamura, Ken Nakamura

Dokumenty pełnotekstowe

A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation od Alex Y. Ge, Abolfazl Arab, Raymond Dai, Albertas Navickas, Lisa Fish, Kristle Garcia, Hosseinali Asgharian, Jackson Goudreau, Sean Lee, Kathryn Keenan, Melissa B. Pappalardi, Michael T. McCabe, Laralynne Przybyla, Hani Goodarzi, Luke A. Gilbert

Dokumenty pełnotekstowe

In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma od S. John Liu, Christopher Zou, Joanna Pak, Alexandra Morse, Dillon Pang, Timothy Casey-Clyde, Ashir A. Borah, David Wu, Kyounghee Seo, Thomas O’Loughlin, Daniel A. Lim, Tomoko Ozawa, Mitchel S. Berger, Roarke A. Kamber, William A. Weiss, David R. Raleigh, Luke A. Gilbert

Dokumenty pełnotekstowe

An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer od Rajdeep Das, Martin Sjöström, Raunak Shrestha, Christopher Yogodzinski, Emily A. Egusa, Lisa N. Chesner, William S. Chen, Jonathan Chou, Donna K. Dang, Jason T. Swinderman, Alex Ge, Junjie T. Hua, Shaheen Kabir, David A. Quigley, Eric J. Small, Alan Ashworth, Felix Y. Feng, Luke A. Gilbert

Dokumenty pełnotekstowe

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors od Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael E Ward, Luke A Gilbert, Martin Kampmann, Jonathan S Weissman, Marco Jost

Dokumenty pełnotekstowe

Exploitable mechanisms of antibody and CAR mediated macrophage cytotoxicity od Tianyi Liu, Meng Zhang, Tatyanah Farsh, Haolong Li, Audrey Kishishita, Abhilash Barpanda, Stanley G. Leung, Jun Zhu, Hyuncheol Jung, Junjie Tony Hua, Xiaolin Zhu, Alexander B. Kim, Young Ah Goo, Minsoo Son, Jaenyeon Kim, Aish Subramanian, Martin Sjöström, Katherine C. Fuh, Jocelyn S. Chapman, Julia Carnevale, Luke A. Gilbert, Aparna Lakkaraju, Peter M. Bruno, David Quigley, Arun P. Wiita, Felix Y. Feng, Carl J. DeSelm

Dokumenty pełnotekstowe