Sökresultat - Laura M Raffield

Analysis of left ventricular mass for African American individuals using multi-ancestry polygenic risk scores: the Jackson Heart Study av Laura M Raffield, Elizabeth Heitman, Douglas McLaurin, Philip Turk, Olivia Affuso

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Characterization of the phenotypic consequences of the Duffy-null genotype av Micah R. Hysong, Megan M. Shuey, Jennifer E. Huffman, Paul Auer, Alexander Reiner, Laura M. Raffield

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Multi-omics integration predicts the incidence of 17 diseases in the UK Biobank av Jiawen Du, Muqing Zhou, Hanling Wang, Jianqiao Wang, Laura M. Raffield, Ruihai Zhou, Yun Li, Can Chen, Quan Sun

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Methylation profile of individuals with sickle cell trait av Ana Gabriela Vasconcelos, Mari Johnson, Yanwei Cai, Li Hsu, Nora Franceschini, Paul L. Auer, Charles Kooperberg, Laura M. Raffield, Alex P. Reiner

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Integration of genetic risk, cardiometabolic diseases, and cognitive impairment among African American adults av Chaitali Dagli, Nicole D. Armstrong, Daeeun Kim, Laura M. Raffield, Hemant K. Tiwari, Mary Cushman, Suzanne E. Judd, Michael Crowe, Virginia J. Howard, Marguerite R. Irvin

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KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS)... av Ranee Chatterjee, Clemontina A Davenport, Laura M Raffield, Nisa Maruthur, Leslie Lange, Elizabeth Selvin, Kenneth Butler, Hsin-Chieh Yeh, James G Wilson, Adolfo Correa, David Edelman, Elizabeth Hauser

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Interferon gamma-induced protein 10 (IP-10) and cardiovascular disease in African Americans. av Colton Leavitt, Neil A Zakai, Paul Auer, Mary Cushman, Ethan M Lange, Emily B Levitan, Nels Olson, Timothy A Thornton, Russell P Tracy, James G Wilson, Leslie A Lange, Alex P Reiner, Laura M Raffield

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A multi-ethnic polygenic risk score for chronic kidney disease is associated with increased risk of hypertension in African American individuals av Aastha Kakar, Elizabeth M. Litkowski, Ashley W. Scadden, Mohammad Y. Anwar, Iain R. Konigsberg, Maggie A. Stanislawski, Natalie C. DuPre, Riten Mitra, Richard Baumgartner, Laura M. Raffield, Ethan M. Lange, Leslie A. Lange, Kira C. Taylor

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Branched chain amino acids harbor distinct and often opposing effects on health and disease av Christy L. Avery, Annie Green Howard, Harold H. Lee, Carolina G. Downie, Moa P. Lee, Sarah H. Koenigsberg, Anna F. Ballou, Michael H. Preuss, Laura M. Raffield, Rina A. Yarosh, Kari E. North, Penny Gordon-Larsen, Mariaelisa Graff

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Protein quantitative trait locus analysis in African American and non-Hispanic White individuals av Yanwei Cai, Mari Johnson, Jeffrey Haessler, Aaron J. Molstad, Shih-Jen Hwang, Roby Joehanes, Joanne M. Murabito, Usman A. Tahir, Nora Franceschini, Robert E. Gerszten, Wei Sun, Daniel Levy, Laura M. Raffield, Charles Kooperberg, Li Hsu, Alexander P. Reiner

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Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI av Quan Sun, Bryce T. Rowland, Jiawen Chen, Anna V. Mikhaylova, Christy Avery, Ulrike Peters, Jessica Lundin, Tara Matise, Steve Buyske, Ran Tao, Rasika A. Mathias, Alexander P. Reiner, Paul L. Auer, Nancy J. Cox, Charles Kooperberg, Timothy A. Thornton, Laura M. Raffield, Yun Li

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Admixture-mapping analysis reveals genetic determinants of the human plasma proteome av Daniel E. Cruz, Shuliang Deng, Usman A. Tahir, Zsu-Zsu Chen, Mark D. Benson, Bjoernar Tuftin, Jiawen Chen, Laurie Farrell, Dongxiao Shen, Mariah Meyer, Ethan Lange, Yan Gao, Michael E. Hall, Russell P. Tracy, Stephen S. Rich, Kent Taylor, Ani Manichaikul, Jerome I. Rotter, Tamar Sofer, James G. Wilson, Robert E. Gerszten, Laura M. Raffield

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Integrating whole genome and transcriptome sequencing to characterize the genetic architecture of isoform variation av Chunyu Liu, Roby Joehanes, Jiantao Ma, Jiuyong Xie, Jian Yang, Mengyao Wang, Tianxiao Huan, Shih-Jen Hwang, Jia Wen, Quan Sun, Cumhur Y. Demirkale, Nancy L. Heard-Costa, Peter Orchard, April P. Carson, Jeffrey W. Haessler, Laura M. Raffield, Alex P. Reiner, Nora Franceschini, Paul L. Auer, Charles Kooperberg, Yun Li, George O’Connor, Joanne M. Murabito, Peter Munson, Daniel Levy

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Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation av Sara Kirmani, Tianxiao Huan, Joseph C. Van Amburg, Roby Joehanes, Md Mesbah Uddin, Ngoc Quynh H. Nguyen, Bing Yu, Jennifer A. Brody, Myriam Fornage, Jan Bressler, Nona Sotoodehnia, David A. Ong, Fabio Puddu, James S. Floyd, Christie M. Ballantyne, Bruce M. Psaty, Laura M. Raffield, Pradeep Natarajan, Karen N. Conneely, Joshua S. Weinstock, April P. Carson, Leslie A. Lange, Kendra Ferrier, Nancy L. Heard-Costa, Joanne Murabito, Alexander G. Bick, Daniel Levy

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African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children av John Muthii Muriuki, Alexander J. Mentzer, Gavin Band, Amanda Y. Chong, Alex W. Macharia, Reagan M. Mogire, Kelvin Mokaya Abuga, Ruth Mitchell, James J. Gilchrist, Emily L. Webb, Francis M. Ndungu, Laura M. Raffield, Lynette Ekunwe, Amy R. Bentley, Sodiomon B. Sirima, Shabir A. Madhi, Adrian V. S. Hill, Andrew M. Prentice, Philip Bejon, Gibran Hemani, George Davey Smith, Manjinder S. Sandhu, Alison M. Elliott, Thomas N. Williams, Adebowale Adeyemo, Sarah H. Atkinson

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Genome‐wide meta‐analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans av Anh N. Do, Wei Zhao, Abigail S. Baldridge, Laura M. Raffield, Kerri L. Wiggins, Sanjiv J. Shah, Stella Aslibekyan, Hemant K. Tiwari, Nita Limdi, Degui Zhi, Colleen M. Sitlani, Kent D. Taylor, Bruce M. Psaty, Nona Sotoodehnia, Jennifer A. Brody, Laura J. Rasmussen‐Torvik, Donald Lloyd‐Jones, Leslie A. Lange, James G. Wilson, Jennifer A. Smith, Sharon L. R. Kardia, Thomas H. Mosley, Ramachandran S. Vasan, Donna K. Arnett, Marguerite R. Irvin

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Canonical correlation analysis for multi-omics: Application to cross-cohort analysis. av Min-Zhi Jiang, François Aguet, Kristin Ardlie, Jiawen Chen, Elaine Cornell, Dan Cruz, Peter Durda, Stacey B Gabriel, Robert E Gerszten, Xiuqing Guo, Craig W Johnson, Silva Kasela, Leslie A Lange, Tuuli Lappalainen, Yongmei Liu, Alex P Reiner, Josh Smith, Tamar Sofer, Kent D Taylor, Russell P Tracy, David J VanDenBerg, James G Wilson, Stephen S Rich, Jerome I Rotter, Michael I Love, Laura M Raffield, Yun Li, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Analysis Working Group

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Admixture-informed polygenic risk reporting using the ePRS framework av Yu-Jyun Huang, Nuzulul Kurniansyah, Matthew O. Goodman, Brian W. Spitzer, Jiongming Wang, Adrienne Stilp, Cecelia Laurie, Paul S. de Vries, Han Chen, Yuan-I Min, Mario Sims, Gina M. Peloso, Xiuqing Guo, Joshua C. Bis, Jennifer A. Brody, Laura M. Raffield, Jennifer A. Smith, Wei Zhao, Jerome I. Rotter, Stephen S. Rich, Susan Redline, Myriam Fornage, Robert Kaplan, Nora Franceschini, Daniel Levy, Alanna C. Morrison, Eric Boerwinkle, Nicholas L. Smith, Charles Kooperberg, Bruce M. Psaty, Sebastian Zöllner, the Trans-Omics for Precision Medicine Consortium, Tamar Sofer

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Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease av Daeeun Kim, Heather M. Highland, Roelof A. J. Smit, Micah R. Hysong, Victoria L. Buchanan, Kristin L. Young, Chi Zhao, Cassandra N. Spracklen, Tuomas O. Kilpeläinen, Boya Guo, Burcu F. Darst, Yanwei Cai, Zhe Wang, Jessica Lundin, Sonja I. Berndt, JoAnn E. Manson, Eirini Marouli, Leslie Lange, Ethan Lange, Myriam Fornage, Christopher R. Gignoux, Christopher A. Haiman, Stephen S. Rich, Steven Buyske, Ruth J. F. Loos, Charles Kooperberg, Ulrike Peters, Christy L. Avery, Penny Gordon-Larsen, Mariaelisa Graff, Laura M. Raffield, Kari E. North

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Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. av Laura M Raffield, Jacob C Ulirsch, Rakhi P Naik, Samuel Lessard, Robert E Handsaker, Deepti Jain, Hyun M Kang, Nathan Pankratz, Paul L Auer, Erik L Bao, Joshua D Smith, Leslie A Lange, Ethan M Lange, Yun Li, Timothy A Thornton, Bessie A Young, Goncalo R Abecasis, Cathy C Laurie, Deborah A Nickerson, Steven A McCarroll, Adolfo Correa, James G Wilson, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Hematology & Hemostasis, Diabetes, and Structural Variation TOPMed Working Groups, Guillaume Lettre, Vijay G Sankaran, Alex P Reiner

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