Zoekresultaten - Laura Codarri Deak

Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibition door Laura Codarri Deak, Masao Hashimoto, Pablo Umaña, Christian Klein

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Advanced cytokine-based immunotherapies: targeted cis-delivery strategies for enhanced anti-tumor efficacy and reduced toxicity door Laurène Pousse, Amrita Manchala, Christian Klein, Laura Codarri Deak

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PD‐1‐Cis IL‐2R Agonism Determines the Predicted Pharmacological Dose Range for the Immunocytokine Eciskafusp Alfa (PD1‐IL2v) door Lucy G. Hutchinson, Thomas D. Lewin, Laura Lauener, Meret Martin‐Facklam, Merlind Muecke, Volker Teichgraeber, Laura Codarri Deak

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Target receptor expression dictates the selective intra-tumoral targeting of CD8+ T cells by eciskafusp alfa in matched PBMCs and TILs from CPI-naïve patients door Amrita Manchala, Amrita Manchala, Eleni Maria Varypataki, Jehad Charo, Pablo Umaña, Christian Klein, Christian Klein, Laura Codarri Deak

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863 Novel radioimmunotherapy for lung cancer: a tumor targeting approach door Pedro Romero, Sara Labiano, Christian Klein, Pablo Umana, Tania Wyss, Christine Trumpfheller, Marie-Catherine Vozenin, Céline Godfroid, Jackeline Romero, Vincent Roh, Laura Codarri Deak, Genrich V Tolstonog

PD-1 cis-targeted IL-2v in combination with radiotherapy inhibits lung cancer growth and remodels the immune microenvironment door Pedro J Romero, Sara Labiano, Gregory Verdeil, Christian Klein, Pablo Umana, Tania Wyss, Christine Trumpfheller, Marie-Catherine Vozenin, Céline Godfroid, Jackeline Romero, Vincent Roh, Genrich V Tolstonog, Chia-Hsien Chuang, Andrea Kelemen, Laura Codarri Deak

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PD1-IL2v expands and induces effector CD8+ TILs, but not Tregs, in the BCG treated orthotopic non-muscle invasive bladder cancer model door Irene Locatelli, Marco Lorenzoni, Chiara Venegoni, Alessia Di Coste, Rita Sorrentino, Jithin Jose, Daniela Maria Cirillo, Patrick Weber, Amrita Manchala, Ralf J. Hosse, Valeria Nicolini, Pablo Umana, Christian Klein, Andrea Salonia, Francesco Montorsi, Matteo Bellone, Marco Moschini, Laura Codarri Deak, Massimo Alfano

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Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors door Alfred Zippelius, Petra Herzig, Pratiksha Gulati, Christian Klein, Marta Trüb, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Marina Natoli, Klas Hatje, Fabian Junker, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Lothar Tietze, Laura Codarri-Deak, Henry Kao

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