Bilaketaren emaitzak - Lars Pache

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure nork Natasha N. Duggan, Tatjana Dragic, Sumit K. Chanda, Lars Pache

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Metascape provides a biologist-oriented resource for the analysis of systems-level datasets nork Yingyao Zhou, Bin Zhou, Lars Pache, Max Chang, Alireza Hadj Khodabakhshi, Olga Tanaseichuk, Christopher Benner, Sumit K. Chanda

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An integrated map of HIV-human protein complexes that facilitate viral infection. nork Dorothea Emig-Agius, Kevin Olivieri, Lars Pache, Hsin Ling Shih, Olga Pustovalova, Marina Bessarabova, John A T Young, Sumit K Chanda, Trey Ideker

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Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu nork Prashant Jain, Guney Boso, Simon Langer, Stephen Soonthornvacharin, Paul D. De Jesus, Quy Nguyen, Kevin C. Olivieri, Alex J. Portillo, Sunnie M. Yoh, Lars Pache, Sumit K. Chanda

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The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription nork Simon Langer, Xin Yin, Arturo Diaz, Alex J. Portillo, David E. Gordon, Umu H. Rogers, John M. Marlett, Nevan J. Krogan, John A. T. Young, Lars Pache, Sumit K. Chanda

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A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor. nork Charlotte A Stoneham, Simon Langer, Paul D De Jesus, Jacob M Wozniak, John Lapek, Thomas Deerinck, Andrea Thor, Lars Pache, Sumit K Chanda, David J Gonzalez, Mark Ellisman, John Guatelli

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Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses nork Dominik Dornfeld, Alexandra H. Dudek, Thibaut Vausselin, Sira C. Günther, Judd F. Hultquist, Sebastian Giese, Daria Khokhlova-Cubberley, Yap C. Chew, Lars Pache, Nevan J. Krogan, Adolfo Garcia-Sastre, Martin Schwemmle, Megan L. Shaw

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HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses nork Simon Langer, Christian Hammer, Kristina Hopfensperger, Lukas Klein, Dominik Hotter, Paul D De Jesus, Kristina M Herbert, Lars Pache, Nikaïa Smith, Johannes A van der Merwe, Sumit K Chanda, Jacques Fellay, Frank Kirchhoff, Daniel Sauter

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Drug target prediction through deep learning functional representation of gene signatures nork Hao Chen, Frederick J. King, Bin Zhou, Yu Wang, Carter J. Canedy, Joel Hayashi, Yang Zhong, Max W. Chang, Lars Pache, Julian L. Wong, Yong Jia, John Joslin, Tao Jiang, Christopher Benner, Sumit K. Chanda, Yingyao Zhou

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Addressing barriers in FAIR data practices for biomedical data nork Laura D. Hughes, Ginger Tsueng, Jack DiGiovanna, Thomas D. Horvath, Luke V. Rasmussen, Tor C. Savidge, Thomas Stoeger, Serdar Turkarslan, Qinglong Wu, Chunlei Wu, Andrew I. Su, Lars Pache, the NIAID Systems Biology Data Dissemination Working Group

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Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice nork Gagandeep Singh, Juan García-Bernalt Diego, Prajakta Warang, Seok-Chan Park, Lauren A. Chang, Moataz Noureddine, Gabriel Laghlali, Yonina Bykov, Matthew Prellberg, Vivian Yan, Sarabjot Singh, Lars Pache, Sara Cuadrado-Castano, Brett Webb, Adolfo García-Sastre, Michael Schotsaert

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Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo nork Lars Pache, Matthew D. Marsden, Peter Teriete, Alex J. Portillo, Dominik Heimann, Jocelyn T. Kim, Mohamed S.A. Soliman, Melanie Dimapasoc, Camille Carmona, Maria Celeridad, Adam M. Spivak, Vicente Planelles, Nicholas D.P. Cosford, Jerome A. Zack, Sumit K. Chanda

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Developing a standardized but extendable framework to increase the findability of infectious disease datasets nork Ginger Tsueng, Marco A. Alvarado Cano, José Bento, Candice Czech, Mengjia Kang, Lars Pache, Luke V. Rasmussen, Tor C. Savidge, Justin Starren, Qinglong Wu, Jiwen Xin, Michael R. Yeaman, Xinghua Zhou, Andrew I. Su, Chunlei Wu, Liliana Brown, Reed S. Shabman, Laura D. Hughes, the NIAID Systems Biology Data Dissemination Working Group

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Global siRNA screen identifies human host factors critical for SARS-CoV-2 replication and late stages of infection. nork Xin Yin, Yuan Pu, Shuofeng Yuan, Lars Pache, Christopher Churas, Stuart Weston, Laura Riva, Lacy M Simons, William J Cisneros, Thomas Clausen, Grace Biddle, Simon Doss-Gollin, Meagan Deming, Paul D De Jesus, Ha Na Kim, Daniel Fuentes, John M Whitelock, Jeffrey D Esko, Megan S Lord, Ignacio Mena, Adolfo García-Sastre, Judd F Hultquist, Matthew B Frieman, Trey Ideker, Dexter Pratt, Laura Martin-Sancho, Sumit K Chanda

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Integrative multi-omics analysis in vivo identifies influenza virus host factors nork Leah P. Shriver, Benjamin J. Polacco, Manon Eckhardt, Max W. Chang, Carles Martínez-Romero, Kayla Adkins-Travis, Celina Cahalane, Kelsey Haas, David A. Stein, Slim Fourati, Laura Martin-Sancho, Giorgi Metreveli, Jeffrey R. Johnson, Raquel Muñoz-Moreno, Billy W. Newton, Robyn M. Kaake, Yuan Zhou, David Jimenez-Morales, John VonDollen, Erik Verschueren, Danielle L. Swaney, Thong T. Nguyen, Erica J. Stevenson, Ethan Stancliffe, Gary J. Patti, Randy Albrecht, Hong M. Moulton, Lars Pache, Rafick P. Sekaly, Christopher Benner, Judd F. Hultquist, Sumit K. Chanda, Adolfo Garcia-Sastre, Nevan J. Krogan

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Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets nork Kelsey M. Haas, Michael J. McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun-Young Kim, Thong T. Nguyen, Billy W. Newton, Matthew Urbanowski, Heejin Kim, Michael A. P. Williams, Veronica V. Rezelj, Alexandra Hardy, Andrea Fossati, Erica J. Stevenson, Ellie Sukerman, Tiffany Kim, Sudhir Penugonda, Elena Moreno, Hannes Braberg, Yuan Zhou, Giorgi Metreveli, Bhavya Harjai, Tia A. Tummino, James E. Melnyk, Margaret Soucheray, Jyoti Batra, Lars Pache, Laura Martin-Sancho, Jared Carlson-Stevermer, Alexander S. Jureka, Christopher F. Basler, Kevan M. Shokat, Brian K. Shoichet, Leah P. Shriver, Jeffrey R. Johnson, Megan L. Shaw, Sumit K. Chanda, Dan M. Roden, Tonia C. Carter, Leah C. Kottyan, Rex L. Chisholm, Jennifer A. Pacheco, Maureen E. Smith, Steven J. Schrodi, Randy A. Albrecht, Marco Vignuzzi, Lorena Zuliani-Alvarez, Danielle L. Swaney, Manon Eckhardt, Steven M. Wolinsky, Kris M. White, Judd F. Hultquist, Robyn M. Kaake, Adolfo García-Sastre, Nevan J. Krogan

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