Resultados da busca - Kim Monkhorst

Relation between intra-abdominal pressure and early intestinal ischemia in rats por Kim Monkhorst, Steven G Strang, Ben van der Hoven, Samir Ali, Esther M M van Lieshout, Oscar J F van Waes, Michael H J Verhofstad

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The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties. por Kim Monkhorst, Bas de Hoon, Iris Jonkers, Eskeatnaf Mulugeta Achame, Wouter Monkhorst, Jos Hoogerbrugge, Eveline Rentmeester, Hans V Westerhoff, Frank Grosveld, J Anton Grootegoed, Joost Gribnau

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Biological and technical factors in the assessment of blood-based tumor mutational burden (bTMB) in patients with NSCLC por Kim Monkhorst, Daniel Klass, Milou Schuurbiers, Zhongyun Huang, Senglor Saelee, Manana Javey, Leonie de Visser, Daan van den Broek, Michel van den Heuvel, Alexander F Lovejoy

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Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine por Krijn K. Dijkstra, Kim Monkhorst, Luuk J. Schipper, Koen J. Hartemink, Egbert F. Smit, Sovann Kaing, Rosa de Groot, Monika C. Wolkers, Hans Clevers, Edwin Cuppen, Emile E. Voest

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External validation of a serum tumor marker algorithm for early prediction of no durable benefit to immunotherapy in metastastic non-small cell lung carcinoma por Milou M. F. Schuurbiers, Freek A. van Delft, Hendrik Koffijberg, Maarten J. IJzerman, Kim Monkhorst, Marjolijn J. L. Ligtenberg, Daan van den Broek, Huub H. van Rossum, Michel M. van den Heuvel

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Identification of protein biomarkers for prediction of response to platinum‐based treatment regimens in patients with non‐small cell lung cancer por Franziska Böttger, Teodora Radonic, Idris Bahce, Kim Monkhorst, Sander R. Piersma, Thang V. Pham, Anne‐Marie C. Dingemans, Lisa M. Hillen, Mariacarmela Santarpia, Elisa Giovannetti, Egbert F. Smit, Sjaak A. Burgers, Connie R. Jimenez

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T cells expanded from renal cell carcinoma display tumor-specific CD137 expression but lack significant IFN-γ, TNF-α or IL-2 production por Saskia D. van Asten, Rosa de Groot, Marleen M. van Loenen, Suzanne M. Castenmiller, Jeroen de Jong, Kim Monkhorst, John B.A.G. Haanen, Derk Amsen, Axel Bex, Robbert M. Spaapen, Monika C. Wolkers

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Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions por Karlijn Hummelink, Mirte Muller, Theodora C. Linders, Vincent van der Noort, Petra M. Nederlof, Paul Baas, Sjaak Burgers, Egbert F. Smit, Gerrit A. Meijer, Michel M. van den Heuvel, Daan van den Broek, Kim Monkhorst

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Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stage II–IIIA NSCLC patients por Daan C. L. Vessies, Milou M. F. Schuurbiers, Vincent van derNoort, Irene Schouten, Theodora C. Linders, Mirthe Lanfermeijer, Kalpana L. Ramkisoensing, Koen J. Hartemink, Kim Monkhorst, Michel M. van denHeuvel, Daan van denBroek

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SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response por Sofía Ibáñez-Molero, Alex van Vliet, Joanna Pozniak, Karlijn Hummelink, Alexandra M. Terry, Kim Monkhorst, Joyce Sanders, Ingrid Hofland, Ewout Landeloos, Yannick Van Herck, Oliver Bechter, Thomas Kuilman, Weiwei Zhong, Jean-Christophe Marine, Lodewyk Wessels, Daniel S. Peeper

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Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products por Suzanne M. Castenmiller, Nandhini Kanagasabesan, Aurélie Guislain, Benoît P. Nicolet, Marleen M. van Loenen, Kim Monkhorst, Alexander A.F.A. Veenhof, Egbert F. Smit, Koen J. Hartemink, John B.A.G. Haanen, Rosa de Groot, Monika C. Wolkers

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Recurrence prediction using circulating tumor DNA in patients with early-stage non-small cell lung cancer after treatment with curative intent: A retrospective validation study. por Milou M F Schuurbiers, Christopher G Smith, Koen J Hartemink, Robert C Rintoul, Davina Gale, Kim Monkhorst, Bas L R Mandos, Anna L Paterson, Daan van den Broek, Nitzan Rosenfeld, Michel M van den Heuvel, LEMA Study Group and the LUCID Study Group

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Feasibility of Intracoronary GLP-1 Eluting CellBead Infusion in Acute Myocardial Infarction por Jaco H. Houtgraaf, Renate De Jong, Kim Monkhorst, Dennie Tempel, Esther Van De Kamp, Wijnand K. Den Dekker, Kushan Kazemi, Imo Hoefer, Gerard Pasterkamp, Andrew L. Lewis, Peter W. Stratford, Christine Wallrapp, Felix Zijlstra, Henricus J. Duckers M.D., Ph.D., FESC, FACC

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Tumor microenvironment shows an immunological abscopal effect in patients with NSCLC treated with pembrolizumab-radiotherapy combination por Kim Monkhorst, Johannes Textor, Michel M van den Heuvel, Katrien Grünberg, Jeroen H A Creemers, Carl G Figdor, I Jolanda M de Vries, Lieke L van der Woude, Mark A J Gorris, Inge M N Wortel, Kiek Verrijp, Berber Piet, Willemijn S M E Theelen

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Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in non-small cell lung cancer. por Willemijn S M E Theelen, Thomas Kuilman, Katja Schulze, Wei Zou, Oscar Krijgsman, Dennis D G C Peters, Sten Cornelissen, Kim Monkhorst, Pranamee Sarma, Teiko Sumiyoshi, Lukas C Amler, Stefan M Willems, Johannes L G Blaauwgeers, Carel J M van Noesel, Daniel S Peeper, Michel M van den Heuvel, Marcin Kowanetz

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Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients por Ekaterina A. Semenova, Min-chul Kwon, Kim Monkhorst, Ji-Ying Song, Rajith Bhaskaran, Oscar Krijgsman, Thomas Kuilman, Dennis Peters, Wieneke A. Buikhuisen, Egbert F. Smit, Colin Pritchard, Miranda Cozijnsen, Jan van der Vliet, John Zevenhoven, Jan-Paul Lambooij, Natalie Proost, Erwin van Montfort, Arno Velds, Ivo J. Huijbers, Anton Berns

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Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE) por Kris G. Samsom, Linda J. W. Bosch, Luuk J. Schipper, Paul Roepman, Ewart de Bruijn, Louisa R. Hoes, Immy Riethorst, Lieke Schoenmaker, Lizet E. van der Kolk, Valesca P. Retèl, Geert W. J. Frederix, Tineke E. Buffart, Jacobus J. M. van der Hoeven, Emile E. Voest, Edwin Cuppen, Kim Monkhorst, Gerrit A. Meijer

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Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile por Rosa De Groot, Marleen M. Van Loenen, Aurélie Guislain, Benoît P. Nicolet, Julian J. Freen-Van Heeren, Onno J.H.M. Verhagen, Michel M. Van Den Heuvel, Jeroen De Jong, Patrick Burger, C.Ellen Van Der Schoot, Robbert M. Spaapen, Derk Amsen, John B. A. G. Haanen, Kim Monkhorst, Koen J. Hartemink, Monika C. Wolkers

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Real-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC por Liesbeth M. Hondelink, MD, Merel Jebbink, MD, Jan H. von der Thüsen, MD, PhD, Danielle Cohen, MD, PhD, Hendrikus J. Dubbink, PhD, Marthe S. Paats, MD, PhD, Anne-Marie C. Dingemans, MD, PhD, Adrianus J. de Langen, MD, PhD, Mirjam C. Boelens, PhD, Egbert F. Smit, MD, PhD, Pieter E. Postmus, MD, PhD, Tom van Wezel, PhD, Kim Monkhorst, MD, PhD

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Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity por Daan van den Broek, T. Jeroen N. Hiltermann, Bonne Biesma, Winand N. M. Dinjens, Nils A. 't Hart, John W. J. Hinrichs, John W. J. Hinrichs, Mathie P. G. Leers, Kim Monkhorst, Matthijs van Oosterhout, Volkher Scharnhorst, Ed Schuuring, Ernst-Jan M. Speel, Michel M. van den Heuvel, Ron H. N. van Schaik, Jan von der Thüsen, Stefan M. Willems, Leonie de Visser, Marjolijn J. L. Ligtenberg, Marjolijn J. L. Ligtenberg

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