Результаты поиска - Kevin D. Read

Development of a Fluorescence-based Trypanosoma cruzi CYP51 Inhibition Assay for Effective Compound Triaging in Drug Discovery Programmes for Chagas Disease. по Jennifer Riley, Stephen Brand, Michael Voice, Ivan Caballero, David Calvo, Kevin D Read

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Temporal and Wash-Out Studies Identify Medicines for Malaria Venture Pathogen Box Compounds with Fast-Acting Activity against Both <i>Trypanosoma cruzi</i> and <i>Trypanosoma bruce... по Melissa L. Sykes, Emily K. Kennedy, Kevin D. Read, Marcel Kaiser, Vicky M. Avery

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Untargeted metabolomics for triaging of cytochrome b inhibitors during Chagas' disease drug discovery. по A Kenneth MacLeod, Lindsay B Tulloch, Michele Tinti, Darren Edwards, Susan Wyllie, Kevin D Read

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Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo. по Katrin Hack, Louise Reilly, Colin Palmer, Kevin D Read, Suzanne Norval, Robert Kime, Kally Booth, John Foerster

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Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania. по Susan Wyllie, Adam J Roberts, Suzanne Norval, Stephen Patterson, Bernardo J Foth, Matthew Berriman, Kevin D Read, Alan H Fairlamb

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A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on t... по Andrew M. Brandon, Lysbeth H. Antonides, Jennifer Riley, Ola Epemolu, Denise A. McKeown, Kevin D. Read, Craig McKenzie

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The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis по Stephen Patterson, Susan Wyllie, Suzanne Norval, Laste Stojanovski, Frederick RC Simeons, Jennifer L Auer, Maria Osuna-Cabello, Kevin D Read, Alan H Fairlamb

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Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition по Julianty Frost, Carles Galdeano, Pedro Soares, Morgan S. Gadd, Katarzyna M. Grzes, Lucy Ellis, Ola Epemolu, Satoko Shimamura, Marcus Bantscheff, Paola Grandi, Kevin D. Read, Doreen A. Cantrell, Sonia Rocha, Alessio Ciulli

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Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening по Andreas Holmqvist, Nur Mehpare Kocaturk, Christina Duncan, Jennifer Riley, Steven Baginski, Graham Marsh, Joel Cresser-Brown, Hannah Maple, Kristiina Juvonen, Gajanan Sathe, Nicola Morrice, Calum Sutherland, Kevin D. Read, William Farnaby

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Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles. по Ning Zhang, Martin Zoltner, Ka-Fai Leung, Paul Scullion, Sebastian Hutchinson, Ricardo C Del Pino, Isabel M Vincent, Yong-Kang Zhang, Yvonne R Freund, Michael R K Alley, Robert T Jacobs, Kevin D Read, Michael P Barrett, David Horn, Mark C Field

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Compounds Reducing Human Sperm Motility as Potential Nonhormonal Contraceptives Identified Using a High-Throughput Phenotypic Screening Platform по Anthony Richardson, Franz S. Gruber, David P. Day, Darren Edwards, Irene Georgiou, Zoe C. Johnston, Halimatu Joji, Sarah Martins da Silva, Rachel Myles, Neil R. Norcross, Kevin D. Read, Jason R. Swedlow, Caroline Wilson, Christopher L. R. Barratt, Ian H. Gilbert

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Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice по Villo Muha, Ritchie Williamson, Rachel Hills, Alison D. McNeilly, Thomas G. McWilliams, Jana Alonso, Marianne Schimpl, Aneika C. Leney, Albert J. R. Heck, Calum Sutherland, Kevin D. Read, Rory J. McCrimmon, Simon P. Brooks, Daan M. F. van Aalten

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Targeting N-myristoylation for therapy of B-cell lymphomas по Erwan Beauchamp, Megan C. Yap, Aishwarya Iyer, Maneka A. Perinpanayagam, Jay M. Gamma, Krista M. Vincent, Manikandan Lakshmanan, Anandhkumar Raju, Vinay Tergaonkar, Soo Yong Tan, Soon Thye Lim, Wei-Feng Dong, Lynne M. Postovit, Kevin D. Read, David W. Gray, Paul G. Wyatt, John R. Mackey, Luc G. Berthiaume

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Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. по Federica Giordani, Daniel Paape, Isabel M Vincent, Andrew W Pountain, Fernando Fernández-Cortés, Eva Rico, Ning Zhang, Liam J Morrison, Yvonne Freund, Michael J Witty, Rosemary Peter, Darren Y Edwards, Jonathan M Wilkes, Justin J J van der Hooft, Clément Regnault, Kevin D Read, David Horn, Mark C Field, Michael P Barrett

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Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs по Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K. Tamaki, Kirsteen I. Buchanan, John Post, Karen Dowers, Sharon M. Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H. Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C. Kim, James M. Bean, Navid Nahiyaan, Kyu Y. Rhee, Qinglan Wang, Vee Y. Tan, Helena I. M. Boshoff, Paul J. Converse, Si-Yang Li, Yong S. Chang, Nader Fotouhi, Anna M. Upton, Eric L. Nuermberger, Dirk Schnappinger, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Paul G. Wyatt, Laura A. T. Cleghorn

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