Risultati della ricerca - John Collinge

The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse. di Julia Grizenkova, Shaheen Akhtar, John Collinge, Sarah E Lloyd

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Sex effects in mouse prion disease incubation time. di Shaheen Akhtar, Adam Wenborn, Sebastian Brandner, John Collinge, Sarah E Lloyd

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Prion protein gene mutation detection using long-read Nanopore sequencing di François Kroll, Athanasios Dimitriadis, Tracy Campbell, Lee Darwent, John Collinge, Simon Mead, Emmanuelle Vire

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Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis. di Ruth Chia, M Howard Tattum, Samantha Jones, John Collinge, Elizabeth M C Fisher, Graham S Jackson

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Isolation of proteinase K-sensitive prions using pronase E and phosphotungstic acid. di Laura D'Castro, Adam Wenborn, Nathalie Gros, Susan Joiner, Sabrina Cronier, John Collinge, Jonathan D F Wadsworth

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Sod1 deficiency reduces incubation time in mouse models of prion disease. di Shaheen Akhtar, Julia Grizenkova, Adam Wenborn, Holger Hummerich, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Sarah E Lloyd

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NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression di David Mengel, Tze How Mok, Akin Nihat, Wen Liu, Robert A. Rissman, Douglas Galasko, Henrik Zetterberg, Simon Mead, John Collinge, Dominic M. Walsh

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Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. di Rocio Castro-Seoane, Holger Hummerich, Trevor Sweeting, M Howard Tattum, Jacqueline M Linehan, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Peter-Christian Klöhn

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HECTD2 is associated with susceptibility to mouse and human prion disease. di Sarah E Lloyd, Emma G Maytham, Hirva Pota, Julia Grizenkova, Eleni Molou, James Uphill, Holger Hummerich, Jerome Whitfield, Michael P Alpers, Simon Mead, John Collinge

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Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein. di Emmanuel A Asante, Jacqueline M Linehan, Michelle Smidak, Andrew Tomlinson, Andrew Grimshaw, Asif Jeelani, Tatiana Jakubcova, Shyma Hamdan, Caroline Powell, Sebastian Brandner, Jonathan D F Wadsworth, John Collinge

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Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein. di Silvia A Purro, Michael Farmer, Elizabeth Noble, Claire J Sarell, Megan Powell, Daniel Yip, Lauren Giggins, Leila Zakka, David X Thomas, Mark Farrow, Andrew J Nicoll, Dominic Walsh, John Collinge

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Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS. di Emmanuel A Asante, Andrew Grimshaw, Michelle Smidak, Tatiana Jakubcova, Andrew Tomlinson, Asif Jeelani, Shyma Hamdan, Caroline Powell, Susan Joiner, Jacqueline M Linehan, Sebastian Brandner, Jonathan D F Wadsworth, John Collinge

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Isolation of a novel human prion strain from a PRNP codon 129 heterozygous vCJD patient. di Fuquan Zhang, Susan Joiner, Jacqueline M Linehan, Florin Pintilii, Tamsin Nazari, Fabio Argentina, Connor Preston, Maged Taema, Thomas J Cunningham, Emmanuel A Asante, Tzehow Mok, Simon Mead, Sebastian Brandner, John Collinge, Jonathan D F Wadsworth

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Genetic variability in CLU and its association with Alzheimer's disease. di Rita J Guerreiro, John Beck, J Raphael Gibbs, Isabel Santana, Martin N Rossor, Jonathan M Schott, Michael A Nalls, Helena Ribeiro, Beatriz Santiago, Nick C Fox, Catarina Oliveira, John Collinge, Simon Mead, Andrew Singleton, John Hardy

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Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6 di Emma Jones, Elizabeth Hill, Jacqueline Linehan, Tamsin Nazari, Adam Caulder, Gemma F. Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin Sandberg, Emmanuelle Viré, Thomas J. Cunningham, Emmanuel A. Asante, Sebastian Brandner, John Collinge, Simon Mead

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Genome wide association study of clinical duration and age at onset of sporadic CJD di Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G. Kovacs, Michael D. Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J. van der Lee, Cornelia M. van Duijn, Pawel P. Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H. Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S. Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead

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Genome wide association study of clinical duration and age at onset of sporadic CJD. di Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G Kovacs, Michael D Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J van der Lee, Cornelia M van Duijn, Pawel P Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead

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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. di Lesley Jones, Peter A Holmans, Marian L Hamshere, Denise Harold, Valentina Moskvina, Dobril Ivanov, Andrew Pocklington, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Jaspreet Singh Pahwa, Nicola Jones, Alexandra Stretton, Angharad R Morgan, Simon Lovestone, John Powell, Petroula Proitsi, Michelle K Lupton, Carol Brayne, David C Rubinsztein, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Kevin Morgan, Kristelle S Brown, Peter A Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Clive Holmes, David Mann, A David Smith, Seth Love, Patrick G Kehoe, Simon Mead, Nick Fox, Martin Rossor, John Collinge, Wolfgang Maier, Frank Jessen, Britta Schürmann, Reinhard Heun, Heike Kölsch, Hendrik van den Bussche, Isabella Heuser, Oliver Peters, Johannes Kornhuber, Jens Wiltfang, Martin Dichgans, Lutz Frölich, Harald Hampel, Michael Hüll, Dan Rujescu, Alison M Goate, John S K Kauwe, Carlos Cruchaga, Petra Nowotny, John C Morris, Kevin Mayo, Gill Livingston, Nicholas J Bass, Hugh Gurling, Andrew McQuillin, Rhian Gwilliam, Panos Deloukas, Ammar Al-Chalabi, Christopher E Shaw, Andrew B Singleton, Rita Guerreiro, Thomas W Mühleisen, Markus M Nöthen, Susanne Moebus, Karl-Heinz Jöckel, Norman Klopp, H-Erich Wichmann, Eckhard Rüther, Minerva M Carrasquillo, V Shane Pankratz, Steven G Younkin, John Hardy, Michael C O'Donovan, Michael J Owen, Julie Williams

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