Resultats de la cerca - Johan Staaf

Tumor purity adjusted beta values improve biological interpretability of high-dimensional DNA methylation data. per Johan Staaf, Mattias Aine

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Kataegis in clinical and molecular subgroups of primary breast cancer per Srinivas Veerla, Johan Staaf

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Perturbation and stability of PAM50 subtyping in population-based primary invasive breast cancer per Srinivas Veerla, Lennart Hohmann, Deborah F. Nacer, Johan Vallon-Christersson, Johan Staaf

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Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p. per Pontus Eriksson, Mattias Aine, Gottfrid Sjödahl, Johan Staaf, David Lindgren, Mattias Höglund

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Improved detection of clinically relevant fusion transcripts in cancer by machine learning classification per Völundur Hafstað, Jari Häkkinen, Malin Larsson, Johan Staaf, Johan Vallon-Christersson, Helena Persson

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Tumour immune characterisation of primary triple-negative breast cancer using automated image quantification of immunohistochemistry-stained immune cells per Suze Roostee, Daniel Ehinger, Mats Jönsson, Bengt Phung, Göran Jönsson, Gottfrid Sjödahl, Johan Staaf, Mattias Aine

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Molecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study per Deborah F. Nacer, Johan Vallon-Christersson, Nicklas Nordborg, Hans Ehrencrona, Anders Kvist, Åke Borg, Johan Staaf

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Comparison of SP142 and 22C3 PD-L1 assays in a population-based cohort of triple-negative breast cancer patients in the context of their clinically established scoring algorithms per Gudbjörg Sigurjonsdottir, Tommaso De Marchi, Anna Ehinger, Johan Hartman, Ana Bosch, Johan Staaf, Fredrika Killander, Emma Niméus

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Complement inhibitor CSMD1 modulates epidermal growth factor receptor oncogenic signaling and sensitizes breast cancer cells to chemotherapy per Chrysostomi Gialeli, Emre Can Tuysuz, Johan Staaf, Safia Guleed, Veronika Paciorek, Matthias Mörgelin, Konstantinos S. Papadakos, Anna M. Blom

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Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours per Jillian Howlin, Helena Cirenajwis, Barbara Lettiero, Johan Staaf, Martin Lauss, Lao Saal, Åke Borg, Sofia Gruvberger-Saal, Göran Jönsson

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Comprehensive comparison of homologous recombination deficiency predictors in early-stage triple-negative breast cancer per Deborah F. Nacer, Srinivas Veerla, Iñaki Sasiain, Jari Häkkinen, Johan Vallon-Christersson, Maria Rossing, Serena Nik-Zainal, Anders Edsjö, Johan Staaf

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Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma per Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian

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Multiomics assessment of lung adenocarcinoma subtypes defined through tumor purity-adjusted DNA methylation per Deborah F. Nacer, Elsa Arbajian, Srinivas Veerla, Mattias Aine, Mats Jönsson, Frida Rosengren, Anna Karlsson, Annette Salomonsson, Sofi Isaksson, Maria Planck, Johan Staaf

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The analytical and clinical validity of AI algorithms to score TILs in TNBC: can we use different machine learning models interchangeably?Research in context per Joan Martínez Vidal, Nikos Tsiknakis, Johan Staaf, Ana Bosch, Anna Ehinger, Emma Nimeus, Roberto Salgado, Yalai Bai, David L. Rimm, Johan Hartman, Balazs Acs

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The DNA methylation landscape of primary triple-negative breast cancer per Mattias Aine, Deborah F. Nacer, Elsa Arbajian, Srinivas Veerla, Anna Karlsson, Jari Häkkinen, Henrik J. Johansson, Frida Rosengren, Johan Vallon-Christersson, Åke Borg, Johan Staaf

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Molecular profiling of the Basal-like intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer per Lennart Hohmann, Deborah F. Nacer, Mattias Aine, Yasin Memari, Daniella Black, Ramsay Bowden, Helen R. Davies, Åke Borg, Johan Vallon-Christersson, Serena Nik-Zainal, Johan Staaf

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A two‐phase epigenome‐wide four‐way gene–smoking interaction study of overall survival for early‐stage non‐small cell lung cancer per Leyi Chen, Xiang Wang, Ning Xie, Zhongwen Zhang, Xiaowen Xu, Maojie Xue, Yuqing Yang, Liya Liu, Li Su, Maria Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Ruyang Zhang

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Distinct mechanisms of resistance to fulvestrant treatment dictate level of ER independence and selective response to CDK inhibitors in metastatic breast cancer per Kamila Kaminska, Nina Akrap, Johan Staaf, Carla L. Alves, Anna Ehinger, Anna Ebbesson, Ingrid Hedenfalk, Lukas Beumers, Srinivas Veerla, Katja Harbst, Sidse Ehmsen, Signe Borgquist, Åke Borg, Alejandro Pérez-Fidalgo, Henrik J. Ditzel, Ana Bosch, Gabriella Honeth

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Genomic characterization of the HER2-enriched intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer per Lennart Hohmann, Kristin Sigurjonsdottir, Ana Bosch Campos, Deborah F. Nacer, Srinivas Veerla, Frida Rosengren, Poojaswini Thimmaraya Reddy, Jari Häkkinen, Nicklas Nordborg, Johan Vallon-Christersson, Yasin Memari, Daniella Black, Ramsay Bowden, Helen R. Davies, Åke Borg, Serena Nik-Zainal, Johan Staaf

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Homologous recombination deficiency in primary ER-positive and HER2-negative breast cancer per Helen R. Davies, Daniella Black, Anders Kvist, Kristín Sigurjónsdóttir, Ana Bosch, Ramsay Bowden, Yasin Memari, Ziqian Chen, Giuseppe Rinaldi, Frida Rosengren, Deborah F. Nacer, Srinivas Veerla, Lennart Hohmann, Nicklas Nordborg, Jari Häkkinen, Johan Vallon-Christersson, Åke Borg, Serena Nik-Zainal, Johan Staaf

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