תוצאות חיפוש - James M Cook

Bisindole Alkaloids from the <i>Alstonia</i> Species: Recent Isolation, Bioactivity, Biosynthesis, and Synthesis מאת Kamal P. Pandey, Md Toufiqur Rahman, James M. Cook

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General Approach to the Total Synthesis of Macroline-Related Sarpagine and Ajmaline Alkaloids מאת Chitra R. Edwankar, Rahul V. Edwankar, Sundari Rallapalli, James M. Cook

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Functional trait mismatch between native and introduced bee pollinators servicing a global fruit crop מאת Olivia M. Bernauer, Michael G. Branstetter, James M. Cook, Simon M. Tierney

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The Impact of Colony Deployment Timing on <i>Tetragonula carbonaria</i> Crop Fidelity and Resource Use in Macadamia Orchards מאת Claire E. Allison, James C. Makinson, Robert N. Spooner-Hart, James M. Cook

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First Total Synthesis of the Unnatural (+)-Talcarpine and (−)‑N4‑Methyl,N4‑21-secotalpinine מאת Kamal Prasad Pandey, Md Toufiqur Rahman, Anna Benko, Gregory H. Imler, Jefferey R. Deschamps, James M. Cook

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Co-flowering plants support diverse pollinator populations and facilitate pollinator visitation to sweet cherry crops מאת Amy-Marie Gilpin, Corey O'Brien, Conrad Kobel, Laura E. Brettell, James M. Cook, Sally A. Power

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Co-Flowering Species Richness Increases Pollinator Visitation to Apple Flowers מאת Amy-Marie Gilpin, Conrad Kobel, Laura E. Brettell, Corey O’Brien, James M. Cook, Sally A. Power

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The Role of Flies as Pollinators of Horticultural Crops: An Australian Case Study with Worldwide Relevance מאת David F Cook, Sasha C Voss, Jonathan T D Finch, Romina C Rader, James M Cook, Cameron J Spurr

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Synthesis and Receptor Binding Studies of α5 GABA_AR Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders מאת Dishary Sharmin, Md Yeunus Mian, Michael Marcotte, Thomas D. Prevot, Etienne Sibille, Jeffrey M. Witkin, James M. Cook

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KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy מאת Jodi L. Smith, Jeremy Wertz, Arnold Lippa, Xingjie Ping, Xiaoming Jin, James M. Cook, Jeffrey M. Witkin, Rok Cerne

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The α6 GABA_A Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome מאת Roberto Cadeddu, Daniel E. Knutson, Laura J. Mosher, Stefanos Loizou, Karen Odeh, Janet L. Fisher, James M. Cook, Marco Bortolato

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Behavioral Domain‐Specific Effects of Positive Modulation of α5 and α6 GABAA Receptors in a Rat Double‐Hit Stress Model מאת Đorđe Đorović, Jovana Aranđelović, Jana Ivanović, Kristina Jezdić, Bojan Batinić, Dishary Sharmin, Prithu Mondal, James M. Cook, Miroslav M. Savić

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Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor <i>N</i>₄-Methyltalpinine מאת Md Toufiqur Rahman, Veera Venkata Naga Phani Babu Tiruveedhula, Michael Rajesh Stephen, Sundari K. Rallapalli, Kamal P. Pandey, James M. Cook

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GABA-A Alpha 2/3 but Not Alpha 1 Receptor Subunit Ligand Inhibits Harmaline and Pimozide-Induced Tremor in Rats מאת Barbara Kosmowska, Martyna Paleczna, Dominika Biała, Justyna Kadłuczka, Jadwiga Wardas, Jeffrey M. Witkin, James M. Cook, Dishary Sharmin, Monika Marcinkowska, Katarzyna Z. Kuter

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Therapeutic effects of KRM-II-81, positive allosteric modulator for α2/3 subunit containing GABAA receptors, in a mouse model of Dravet syndrome מאת Sachiko Nakakubo, Yasuyoshi Hiramatsu, Takeru Goto, Syuhei Kimura, Masashi Narugami, Midori Nakajima, Yuki Ueda, Hideaki Shiraishi, Atsushi Manabe, Dishary Sharmin, James M. Cook, Kiyoshi Egawa

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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach מאת Jelena R. Mitrović, Branka Divović-Matović, Daniel E. Knutson, Jelena B. Đoković, Aleksandar Kremenović, Vladimir D. Dobričić, Danijela V. Randjelović, Ivana Pantelić, James M. Cook, Miroslav M. Savić, Snežana D. Savić

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A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABA_A Receptor מאת Guanguan Li, Amanda N. Nieman, Md Yeunus Mian, Nicolas M. Zahn, Brandon N. Mikulsky, Michael M. Poe, Kashi R. Methuku, Yongfeng Liu, James M. Cook, Douglas C. Stafford, Leggy A. Arnold

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Intravenous Nanoemulsions Loaded with Phospholipid Complex of a Novel Pyrazoloquinolinone Ligand for Enhanced Brain Delivery מאת Tijana Stanković, Tanja Ilić, Branka Divović Matović, Milos Petkovic, Vladimir Dobričić, Ivan Jančić, Biljana Bufan, Kristina Jezdić, Jelena Đoković, Ivana Pantelić, Danijela Randjelović, Dishary Sharmin, James M. Cook, Miroslav M. Savić, Snežana Savić

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Parenteral Nanoemulsion for Optimized Delivery of GL-II-73 to the Brain—Comparative In Vitro Blood–Brain Barrier and In Vivo Neuropharmacokinetic Evaluation מאת Kristina Jezdić, Jelena Đoković, Ivan Jančić, Tanja Ilić, Biljana Bufan, Bojan Marković, Jana Ivanović, Tijana Stanković, Nebojša D. Cekić, Vassiliki Papadimitriou, Dishary Sharmin, Prithu Mondal, James M. Cook, Snežana D. Savić, Miroslav M. Savić

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KRM-II-81, a β3-Preferring GABA_A Receptor Potentiator, Blocks Handling-Induced Seizures in Theiler’s Murine Encephalomyelitis Virus-Infected Mice מאת Dishary Sharmin, Kamal P. Pandey, Lalit K. Golani, Sepideh Rezvanian, Md Yeunus Mian, Janet L. Fisher, Arnold Lippa, James M. Cook, Daniel P. Radin, Jodi L. Smith, Jeffrey M. Witkin, Hana Shafique, Rok Cerne

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