Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure

by Nicholas C. Wu, Ian A. Wilson
Published 2020-09-01

Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses.

by Tshidi Tsibane, Damian C Ekiert, Jens C Krause, Osvaldo Martinez, James E Crowe, Ian A Wilson, Christopher F Basler
Published 2012-01-01

Crystal structure of a two-subunit TrkA octameric gating ring assembly.

by Marc C Deller, Hope A Johnson, Mitchell D Miller, Glen Spraggon, Marc-André Elsliger, Ian A Wilson, Scott A Lesley
Published 2015-01-01

Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans

by Seth J. Zost, Juhye Lee, Megan E. Gumina, Kaela Parkhouse, Carole Henry, Nicholas C. Wu, Chang-Chun D. Lee, Ian A. Wilson, Patrick C. Wilson, Jesse D. Bloom, Scott E. Hensley
Published 2019-12-01

Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design

by Kimmo Rantalainen, Zachary T. Berndsen, Sasha Murrell, Liwei Cao, Oluwarotimi Omorodion, Jonathan L. Torres, Mengyu Wu, Jeffrey Umotoy, Jeffrey Copps, Pascal Poignard, Elise Landais, James C. Paulson, Ian A. Wilson, Andrew B. Ward
Published 2018-06-01

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response.

by Merika Treants Koday, Jorgen Nelson, Aaron Chevalier, Michael Koday, Hannah Kalinoski, Lance Stewart, Lauren Carter, Travis Nieusma, Peter S Lee, Andrew B Ward, Ian A Wilson, Ashley Dagley, Donald F Smee, David Baker, Deborah Heydenburg Fuller
Published 2016-02-01

Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake.

by Qingping Xu, Neil D Rawlings, Carol L Farr, Hsiu-Ju Chiu, Joanna C Grant, Lukasz Jaroszewski, Heath E Klock, Mark W Knuth, Mitchell D Miller, Dana Weekes, Marc-André Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Ian A Wilson
Published 2011-01-01

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

by James E. Voss, Raiees Andrabi, Laura E. McCoy, Natalia de Val, Roberta P. Fuller, Terrence Messmer, Ching-Yao Su, Devin Sok, Salar N. Khan, Fernando Garces, Laura K. Pritchard, Richard T. Wyatt, Andrew B. Ward, Max Crispin, Ian A. Wilson, Dennis R. Burton
Published 2017-10-01

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

by James E. Voss, Raiees Andrabi, Laura E. McCoy, Natalia de Val, Roberta P. Fuller, Terrence Messmer, Ching-Yao Su, Devin Sok, Salar N. Khan, Fernando Garces, Laura K. Pritchard, Richard T. Wyatt, Andrew B. Ward, Max Crispin, Ian A. Wilson, Dennis R. Burton
Published 2018-01-01

Structure of a novel winged-helix like domain from human NFRKB protein.

by Abhinav Kumar, Sabine Möcklinghoff, Fumiaki Yumoto, Lukasz Jaroszewski, Carol L Farr, Anna Grzechnik, Phuong Nguyen, Christian X Weichenberger, Hsiu-Ju Chiu, Heath E Klock, Marc-André Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Bruce R Conklin, Robert J Fletterick, Ian A Wilson
Published 2012-01-01

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

by Ronald Derking, Gabriel Ozorowski, Kwinten Sliepen, Anila Yasmeen, Albert Cupo, Jonathan L Torres, Jean-Philippe Julien, Jeong Hyun Lee, Thijs van Montfort, Steven W de Taeye, Mark Connors, Dennis R Burton, Ian A Wilson, Per-Johan Klasse, Andrew B Ward, John P Moore, Rogier W Sanders
Published 2015-03-01

A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.

by Nathan Beutler, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Randall S MacGill, Elijah Garcia, Jaeson Calla, Mara Parren, Linlin Yang, Wayne Volkmuth, Emily Locke, Jason A Regules, Sheetij Dutta, Daniel Emerling, Angela M Early, Daniel E Neafsey, Elizabeth A Winzeler, C Richter King, Fidel Zavala, Dennis R Burton, Ian A Wilson, Thomas F Rogers
Published 2022-03-01

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

by P J Klasse, Thomas J Ketas, Christopher A Cottrell, Gabriel Ozorowski, Gargi Debnath, Diawoye Camara, Erik Francomano, Pavel Pugach, Rajesh P Ringe, Celia C LaBranche, Marit J van Gils, Christine A Bricault, Dan H Barouch, Shane Crotty, Guido Silvestri, Sudhir Kasturi, Bali Pulendran, Ian A Wilson, David C Montefiori, Rogier W Sanders, Andrew B Ward, John P Moore
Published 2018-02-01

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

by Alba Torrents de la Peña, Jean-Philippe Julien, Steven W. de Taeye, Fernando Garces, Miklos Guttman, Gabriel Ozorowski, Laura K. Pritchard, Anna-Janina Behrens, Eden P. Go, Judith A. Burger, Edith E. Schermer, Kwinten Sliepen, Thomas J. Ketas, Pavel Pugach, Anila Yasmeen, Christopher A. Cottrell, Jonathan L. Torres, Charlotte D. Vavourakis, Marit J. van Gils, Celia LaBranche, David C. Montefiori, Heather Desaire, Max Crispin, Per Johan Klasse, Kelly K. Lee, John P. Moore, Andrew B. Ward, Ian A. Wilson, Rogier W. Sanders
Published 2017-08-01