Resultados de procura - H. Mach

67 Lipid metabolism and synthesis pathway analysis of Sigma-2 Receptor/TMEM97 in breast cancer cells por Aladdin Riad, David Mankof, Robert H. Mach

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Automation of the Radiosynthesis of Six Different 18F-labeled radiotracers on the AllinOne por Shihong Li, Alexander Schmitz, Hsiaoju Lee, Robert H. Mach

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Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development por Chia-Ju Hsieh, Sam Giannakoulias, E. James Petersson, Robert H. Mach

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PET Imaging of Microglial Activation—Beyond Targeting TSPO por Bieneke Janssen, Danielle J. Vugts, Albert D. Windhorst, Robert H. Mach

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Dopamine D1, D2, D3 receptors, vesicular monoamine transporter type-2 (VMAT2) and dopamine transporter (DAT) densities in aged human brain. por Jianjun Sun, Jinbin Xu, Nigel J Cairns, Joel S Perlmutter, Robert H Mach

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A nanoluciferase complementation-based assay for monitoring β-arrestin2 recruitment to the dopamine D3 receptor por Viktor Burström, Kuiying Xu, Emilio Garro-Martínez, Robert H. Mach, Kristoffer Sahlholm, Nibal Betari

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Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase‑1 Inhibitors with Decreased P‑Glycoprotein Interactions por Sean W. Reilly, Laura N. Puentes, Chia-Ju Hsieh, Mehran Makvandi, Robert H. Mach

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Automated synthesis of [11C]L-glutamine on Synthra HCN plus synthesis module por Prashanth K. Padakanti, Shihong Li, Alexander Schmitz, David Mankoff, Robert H. Mach, Hsiaoju S. Lee

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Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imagin... por Devika P Bagchi, Lihai Yu, Joel S Perlmutter, Jinbin Xu, Robert H Mach, Zhude Tu, Paul T Kotzbauer

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Design and Synthesis of D₃R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies por Gui-Long Tian, Chia-Ju Hsieh, Michelle Taylor, Ji Youn Lee, Robert R. Luedtke, Robert H. Mach

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Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods por Chia-Ju Hsieh, Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu, Robert R. Luedtke, Robert H. Mach

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In vitro characterization of [125I]HY-3-24, a selective ligand for the dopamine D3 receptor por Ji Youn Lee, Ho Young Kim, Paul Martorano, Aladdin Riad, Michelle Taylor, Robert R. Luedtke, Robert H. Mach

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Characterization of Sigma-2 Receptor—Specific Binding Sites Using [³H]DTG and [¹²⁵I]RHM-4 por Chi-Chang Weng, Aladdin Riad, Brian P. Lieberman, Kuiying Xu, Xin Peng, John L. Mikitsh, Robert H. Mach

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Evaluation of Substituted <i>N</i>-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands por Boeun Lee, Michelle Taylor, Suzy A. Griffin, Tamara McInnis, Nathalie Sumien, Robert H. Mach, Robert R. Luedtke

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Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue por Jennifer Y. O’Shea, Dhruva D. Dhavale, Helen Hwang, Zachary Smith, Thomas J. A. Graham, Robert H. Mach, Paul T. Kotzbauer

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Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro por Chia-Ju Hsieh, Kuiying Xu, Iljung Lee, Thomas J. A. Graham, Zhude Tu, Dhruva Dhavale, Paul Kotzbauer, Robert H. Mach

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Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein por Xiang Zhang, Hongjun Jin, Prashanth K. Padakanti, Junfeng Li, Hao Yang, Jinda Fan, Robert H. Mach, Paul Kotzbauer, Zhude Tu

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[¹⁸F]NOS PET Brain Imaging Suggests Elevated Neuroinflammation in Idiopathic Parkinson’s Disease por Robert K. Doot, Anthony J. Young, Ilya M. Nasrallah, Reagan R. Wetherill, Andrew Siderowf, Robert H. Mach, Jacob G. Dubroff

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Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer por Chi-Chang Weng, Chao-Chih Chiang, Yi-Hsiu Chung, Yi-Pei Ho, Yu-Chuan Chang, Ing-Tsung Hsiao, Robert H. Mach

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Translocator protein in late stage Alzheimer’s disease and Dementia with Lewy bodies brains por Jinbin Xu, Jianjun Sun, Richard J. Perrin, Robert H. Mach, Kelly R. Bales, John C. Morris, Tammie L. S. Benzinger, David M. Holtzman

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