Søgeresultater - Gregory M Cook

Bacillus subtilis as a platform for molecular characterisation of regulatory mechanisms of Enterococcus faecalis resistance against cell wall antibiotics. af Chong Fang, Emanuel Stiegeler, Gregory M Cook, Thorsten Mascher, Susanne Gebhard

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The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis af Natalie J. E. Waller, Chen-Yi Cheung, Gregory M. Cook, Matthew B. McNeil

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Inhalable Dry Powder of Bedaquiline for Pulmonary Tuberculosis: In Vitro Physicochemical Characterization, Antimicrobial Activity and Safety Studies af Mohammad A. M. Momin, Bhamini Rangnekar, Shubhra Sinha, Chen-Yi Cheung, Gregory M. Cook, Shyamal C. Das

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Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion af William J Allen, Robin A Corey, Daniel W Watkins, A Sofia F Oliveira, Kiel Hards, Gregory M Cook, Ian Collinson

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Remission spectroscopy resolves the mechanism of action of bedaquiline within living mycobacteria af Suzanna H. Harrison, Rowan C. Walters, Chen-Yi Cheung, Roger J. Springett, Gregory M. Cook, Morwan M. Osman, James N. Blaza

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M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments af Nitin Pal Kalia, Samsher Singh, Kiel Hards, Chen-Yi Cheung, Ekaterina Sviriaeva, Amir Banaei-Esfahani, Ruedi Aebersold, Michael Berney, Gregory M. Cook, Kevin Pethe

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A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis af Xirong Tian, Xirong Tian, Xirong Tian, Xirong Tian, Yamin Gao, Yamin Gao, Yamin Gao, Yamin Gao, Chunyu Li, Chunyu Li, Chunyu Li, Chunyu Li, Wanli Ma, Wanli Ma, Wanli Ma, Wanli Ma, Jingran Zhang, Jingran Zhang, Jingran Zhang, Jingran Zhang, Yanan Ju, Yanan Ju, Yanan Ju, Yanan Ju, Jie Ding, Jie Ding, Jie Ding, Jie Ding, Sanshan Zeng, Sanshan Zeng, Sanshan Zeng, Sanshan Zeng, H. M. Adnan Hameed, H. M. Adnan Hameed, H. M. Adnan Hameed, H. M. Adnan Hameed, Htin Lin Aung, Htin Lin Aung, Htin Lin Aung, Nanshan Zhong, Gregory M. Cook, Gregory M. Cook, Gregory M. Cook, Gregory M. Cook, Jinxing Hu, Jinxing Hu, Tianyu Zhang, Tianyu Zhang, Tianyu Zhang, Tianyu Zhang, Tianyu Zhang

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Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues af Yuanyuan Zhao, Kang Duan, Youlong Fan, Shengrong Li, Liyan Huang, Zhengchao Tu, Hongyan Sun, Gregory M. Cook, Jing Yang, Pinghua Sun, Yi Tan, Ke Ding, Zhengqiu Li

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A CRISPR-guided mutagenic DNA polymerase strategy for the detection of antibiotic-resistant mutations in M. tuberculosis af Siyuan Feng, Lujie Liang, Cong Shen, Daixi Lin, Jiachen Li, Lingxuan Lyu, Wanfei Liang, Lan-lan Zhong, Gregory M. Cook, Yohei Doi, Cha Chen, Guo-bao Tian

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Comparative genomics of endemic Staphylococcus aureus ST1 in New Zealand af Emma M. Voss, Gregory M. Cook, Christine Couldrey, Scott A. Ferguson, Chad Harland, Ali Karkaba, Scott McDougall, Sergio E. Morales, Jack Rolfe, James E. Ussher, Rhys T. White, Liam Williams, John Williamson

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Amino acid 17 in QRDR of Gyrase A plays a key role in fluoroquinolones susceptibility in mycobacteria af Shuai Wang, Jingran Zhang, H. M. Adnan Hameed, Jie Ding, Ping Guan, Xiange Fang, Jiacong Peng, Biyi Su, Shangming Ma, Yaoju Tan, Gregory M. Cook, Guoliang Zhang, Yongping Lin, Nanshan Zhong, Jinxing Hu, Jianxiong Liu, Tianyu Zhang

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Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis af Zhiqi Xiong, Xiaolin Yang, Shule Wang, Caitlan J. Smart, Hazel M. Sisson, Zhenli Lin, Tianyu Hu, Yuting Ran, Chuyao Xu, Xiuna Yang, Yao Zhao, William J. Jowsey, Gregory M. Cook, Matthew B. McNeil, Luke W. Guddat, Zihe Rao, Bing Zhang

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ClpC1-targeting peptide natural products differentially dysregulate the proteome of Mycobacterium tuberculosis af Isabel K. Barter, Max J. Bedding, Julia Leodolter, Joshua W. C. Maxwell, Paige M. E. Hawkins, Maxwell T. Stevens, Matthew B. McNeil, William J. Jowsey, Trixie Wang, Diana Quan, Sabryna Junker, Manuela Flórido, Daniel Hesselson, Gregory M. Cook, Tim Clausen, Warwick J. Britton, Mark Larance, Richard J. Payne

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Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis af XinYue Wang, William J. Jowsey, Chen-Yi Cheung, Caitlan J. Smart, Hannah R. Klaus, Noon EJ Seeto, Natalie JE Waller, Michael T. Chrisp, Amanda L. Peterson, Boatema Ofori-Anyinam, Emily Strong, Brunda Nijagal, Nicholas P. West, Jason H. Yang, Peter C. Fineran, Gregory M. Cook, Simon A. Jackson, Matthew B. McNeil

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Arabinosyltransferase C Mediates Multiple Drugs Intrinsic Resistance by Altering Cell Envelope Permeability in Mycobacterium abscessus af Shuai Wang, Xiaoyin Cai, Wei Yu, Sheng Zeng, Jingran Zhang, Lingmin Guo, Yamin Gao, Zhili Lu, H. M. Adnan Hameed, Cuiting Fang, Xirong Tian, Buhari Yusuf, Chiranjibi Chhotaray, M. D. Shah Alam, Buchang Zhang, Honghua Ge, Dmitry A. Maslov, Gregory M. Cook, Jiacong Peng, Yongping Lin, Nanshan Zhong, Guoliang Zhang, Tianyu Zhang

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Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis af Bei Shi Lee, Kiel Hards, Curtis A Engelhart, Erik J Hasenoehrl, Nitin P Kalia, Jared S Mackenzie, Ekaterina Sviriaeva, Shi Min Sherilyn Chong, Malathy Sony S Manimekalai, Vanessa H Koh, John Chan, Jiayong Xu, Sylvie Alonso, Marvin J Miller, Adrie J C Steyn, Gerhard Grüber, Dirk Schnappinger, Michael Berney, Gregory M Cook, Garrett C Moraski, Kevin Pethe

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Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria af Rhys Grinter, Blair Ney, Rajini Brammananth, Christopher K. Barlow, Paul R. F. Cordero, David L. Gillett, Thierry Izoré, Max J. Cryle, Liam K. Harold, Gregory M. Cook, George Taiaroa, Deborah A. Williamson, Andrew C. Warden, John G. Oakeshott, Matthew C. Taylor, Paul K. Crellin, Colin J. Jackson, Ralf B. Schittenhelm, Ross L. Coppel, Chris Greening

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Dormancy regulon reduction was pivotal to the evolution of Mycobacterium tuberculosis af Matthew Silcocks, James P. Lingford, Chen-Yi Cheung, William J. Jowsey, Rita M. McCall, Christopher D. Rae, Liam K. Harold, David Edwards, Evan Pepper-Tunick, Stephanie L. Neville, Megan J. Maher, Aleix Canalda-Baltrons, Xuling Chang, Phan Vuong Khac Thai, Kathryn E. Holt, Nitin S. Baliga, Gregory M. Cook, Thomas R. Hawn, Nguyen Thuy Thuong Thuong, Maxine Caws, Chris Greening, Christopher A. McDevitt, Jeffery S. Cox, Matthew B. McNeil, Sarah J. Dunstan

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