Cell cycle regulators control mesoderm specification in human pluripotent stem cells

by Yiangou, Loukia, Grandy, Rodrigo A., Osnato, Anna, Ortmann, Daniel, Sinha, Sanjay, Vallier, Ludovic
Published in J Biol Chem (2019)

The Ric-8B Gene Is Highly Expressed in Proliferating Preosteoblastic Cells and Downregulated during Osteoblast Differentiation in a SWI/SNF- and C/EBPβ-Mediated Manner

by Grandy, Rodrigo, Sepulveda, Hugo, Aguilar, Rodrigo, Pihan, Philippe, Henriquez, Berta, Olate, Juan, Montecino, Martin
Published 2011

A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation

by Eldridge, Cara B., Allen, Finian J., Crisp, Alastair, Grandy, Rodrigo A., Vallier, Ludovic, Sale, Julian E.
Published in Stem Cell Reports (2020)

Expression of Ribosomal RNA and Protein Genes in Human Embryonic Stem Cells is Associated with the Activating H3K4me3 Histone Mark

by Zaidi, Sayyed K., Boyd, Joseph R., Grandy, Rodrigo, Medina, Ricardo, Lian, Jane B., Stein, Gary S., Stein, Janet L.
Published in J Cell Physiol (2016)

Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation

by Canu, Giovanni, Athanasiadis, Emmanouil, Grandy, Rodrigo A., Garcia-Bernardo, Jose, Strzelecka, Paulina M., Vallier, Ludovic, Ortmann, Daniel, Cvejic, Ana
Published in Genome Biol (2020)

Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle

by VanOudenhove, Jennifer J., Grandy, Rodrigo A., Ghule, Prachi N., Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary S.
Published in J Cell Physiol (2017)

The Abbreviated Pluripotent Cell Cycle

by Kapinas, Kristina, Grandy, Rodrigo, Ghule, Prachi, Medina, Ricardo, Becker, Klaus, Pardee, Arthur, Zaidi, Sayyed K., Lian, Jane, Stein, Janet, van Wijnen, Andre, Stein, Gary
Published 2013

Bookmarking Target Genes in Mitosis: A Shared Epigenetic Trait of Phenotypic Transcription Factors and Oncogenes?

by Zaidi, Sayyed K., Grandy, Rodrigo A., Lopez-Camacho, Cesar, Montecino, Martin M., van Wijnen, Andre J., Lian, Jane B., Stein, Janet L., Stein, Gary S.
Published 2014

A Functional N-terminal Domain in C/EBPβ-LAP* is Required for Interacting with SWI/SNF and to Repress Ric-8B Gene Transcription in Osteoblasts

by Aguilar, Rodrigo, Grandy, Rodrigo, Meza, Daniel, Sepulveda, Hugo, Pihan, Philippe, van Wijnen, Andre J., Lian, Jane B., Stein, Gary S., Stein, Janet L., Montecino, Martin
Published 2014

Lineage-Specific Early Differentiation of Human Embryonic Stem Cells Requires a G2 Cell Cycle Pause

by VanOudenhove, Jennifer J., Grandy, Rodrigo A., Ghule, Prachi N., del Rio, Roxana, Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary S.
Published in Stem Cells (2016)

The Dynamic Architectural and Epigenetic Nuclear Landscape: Developing the Genomic Almanac of Biology and Disease

by Tai, Phillip W. L., Zaidi, Sayyed K., Wu, Hai, Grandy, Rodrigo A., Montecino, Martin M., van Wijnen, André J., Lian, Jane B., Stein, Gary S., Stein, Janet L.
Published 2014

The Architectural Organization of Human Stem Cell Cycle Regulatory Machinery

by Stein, Gary S., Stein, Janet L., Wijnen, Andre van J, Lian, Jane B., Montecino, Martin, Medina, Ricardo, Kapinas, Kristie, Ghule, Prachi, Grandy, Rodrigo, Zaidi, Sayyed K., Becker, Klaus A.
Published 2012

Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation

by Grandy, Rodrigo A., Whitfield, Troy W., Wu, Hai, Fitzgerald, Mark P., VanOudenhove, Jennifer J., Zaidi, Sayyed K., Montecino, Martin A., Lian, Jane B., van Wijnen, André J., Stein, Janet L., Stein, Gary S.
Published in Mol Cell Biol (2016)

Method to Synchronize Cell Cycle of Human Pluripotent Stem Cells without Affecting Their Fundamental Characteristics

by Yiangou, Loukia, Grandy, Rodrigo A., Morell, Carola M., Tomaz, Rute A., Osnato, Anna, Kadiwala, Juned, Muraro, Daniele, Garcia-Bernardo, Jose, Nakanoh, Shota, Bernard, William G., Ortmann, Daniel, McCarthy, Davis J., Simonic, Ingrid, Sinha, Sanjay, Vallier, Ludovic
Published in Stem Cell Reports (2018)

The SMAD2/3 interactome reveals that TGFβ controls m(6)A mRNA methylation in pluripotency

by Bertero, Alessandro, Brown, Stephanie, Madrigal, Pedro, Osnato, Anna, Ortmann, Daniel, Yiangou, Loukia, Kadiwala, Juned, Hubner, Nina C., de los Mozos, Igor Ruiz, Sadee, Christoph, Lenaerts, An-Sofie, Nakanoh, Shota, Grandy, Rodrigo, Farnell, Edward, Ule, Jernej, Stunnenberg, Hendrik G., Mendjan, Sasha, Vallier, Ludovic
Published in Nature (2018)