Bilaketaren emaitzak - Graham MacLeod

The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma nork Thibault Houles, Jonathan Boucher, Geneviève Lavoie, Graham MacLeod, Sichun Lin, Stephane Angers, Philippe P. Roux

Testu osoa

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ. nork Amanda M Opaluch, Monika Schneider, Chih-yuan Chiang, Quy T Nguyen, Ana M Maestre, Lubbertus C F Mulder, Ismael Secundino, Paul D De Jesus, Renate König, Viviana Simon, Victor Nizet, Graham MacLeod, Susannah Varmuza, Ana Fernandez-Sesma, Sumit K Chanda

Testu osoa

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells nork Graham MacLeod, Danielle A. Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle M. Kushida, Helen Yu, Fiona J. Coutinho, Florence M.G. Cavalli, Ian Restall, Xiaoguang Hao, Traver Hart, H. Artee Luchman, Samuel Weiss, Peter B. Dirks, Stephane Angers

Testu osoa

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma nork Alexandria DeCarlo, Graham MacLeod, Carolina Fernandes da Silva, Li Qing Shen, Julija Povilaikaite, Madeline Deane, Lucas Aragao, Mariska Sie, Deborah Termini, Jonathan Magee, Brian Gudenas, Sneha Sukumaran, Frederic Charron, Richard Marcellus, Rima Al-Awar, Ahmed Aman, Denis Reynaud, Amarine Trolat, Leanne Wybenga-Groot, Uri Tabori, Carolina Nör, Shane M. Harding, Michael F. Moran, Paul A. Northcott, Peter Dirks, Stephane Angers, Vijay Ramaswamy

Testu osoa

Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils nork Benoît Vanderperre, Amitha Muraleedharan, Marie-France Dorion, Frédérique Larroquette, Esther Del Cid Pellitero, Nishani Rajakulendran, Carol X.-Q. Chen, Roxanne Larivière, Charlotte Michaud-Tardif, Thomas Goiran, Rony Chidiac, Damien Lipuma, Graham MacLeod, Rhalena Thomas, Zhangjie Wang, Wolfgang E. Reintsch, Wen Luo, Irina Shlaifer, Fuming Zhang, Ke Xia, Zachary Steinhart, Robert J. Linhardt, Jean-François Trempe, Jian Liu, Thomas M. Durcan, Stephane Angers, Edward A. Fon

Testu osoa

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival nork Paul Guilhamon, Charles Chesnelong, Michelle M Kushida, Ana Nikolic, Divya Singhal, Graham MacLeod, Seyed Ali Madani Tonekaboni, Florence MG Cavalli, Christopher Arlidge, Nishani Rajakulendran, Naghmeh Rastegar, Xiaoguang Hao, Rozina Hassam, Laura J Smith, Heather Whetstone, Fiona J Coutinho, Bettina Nadorp, Katrina I Ellestad, H Artee Luchman, Jennifer Ai-wen Chan, Molly S Shoichet, Michael D Taylor, Benjamin Haibe-Kains, Samuel Weiss, Stephane Angers, Marco Gallo, Peter B Dirks, Mathieu Lupien

Testu osoa