Targeting Amino Acid Metabolic Vulnerabilities in Myeloid Malignancies

by Fultang, Livingstone, Gneo, Luciana, De Santo, Carmela, Mussai, Francis J.
Published in Front Oncol (2021)

TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation

by Farina, Antonietta Rosella, Cappabianca, Lucia, Gneo, Luciana, Ruggeri, Pierdomenico, Mackay, Andrew Reay
Published in Oncotarget (2017)

Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity

by Farina, Antonietta Rosella, Cappabianca, Lucia, Ruggeri, Pierdomenico, Gneo, Luciana, Maccarone, Rita, Mackay, Andrew Reay
Published in Oncotarget (2015)

TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII o...

by Gneo, Luciana, Ruggeri, Pierdomenico, Cappabianca, Lucia, Farina, Antonietta Rosella, Ianni, Natalia Di, Mackay, Andrew Reay
Published in Oncotarget (2016)

The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII

by Farina, Antonietta Rosella, Cappabianca, Lucia, Ruggeri, Pierdomenico, Gneo, Luciana, Pellegrini, Cristina, Fargnoli, Maria-Concetta, Mackay, Andrew Reay
Published in J Exp Clin Cancer Res (2018)

Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma

by Fultang, Livingstone, Gamble, Laura D., Gneo, Luciana, Berry, Andrea M., Egan, Sharon A., De Bie, Fenna, Yogev, Orli, Eden, Georgina L., Booth, Sarah, Brownhill, Samantha, Vardon, Ashley, McConville, Carmel M., Cheng, Paul N., Norris, Murray D., Etchevers, Heather C., Murray, Jayne, Ziegler, David S., Chesler, Louis, Schmidt, Ronny, Burchill, Susan A., Haber, Michelle, De Santo, Carmela, Mussai, Francis
Published in Cancer Res (2018)