Evaluation of the Pharmacokinetics and Pharmacodynamics of Prasugrel in Japanese Elderly Subjects

par Hasunuma, Tomoko, Fukase, Hiroyuki, Miyazaki, Atsuhiro, Nishikawa, Yasuhiro
Publié dans Clin Drug Investig (2017)

Comparison of levocetirizine pharmacokinetics after single doses of levocetirizine oral solution and cetirizine dry syrup in healthy Japanese male subjects

par Ino, Hiroko, Hara, Katsutoshi, Honma, Gosuke, Doi, Yohei, Fukase, Hiroyuki
Publié dans J Drug Assess (2014)

Pharmacokinetics, Safety, and Tolerability of Cefiderocol, a Novel Siderophore Cephalosporin for Gram-Negative Bacteria, in Healthy Subjects

par Saisho, Yutaka, Katsube, Takayuki, White, Scott, Fukase, Hiroyuki, Shimada, Jingoro
Publié dans Antimicrob Agents Chemother (2018)

Food Effect on a Single High Dose of Carotegrast Methyl, an Oral Antagonist of α4-Integrin, in Healthy Male Subjects: A Randomised, Placebo-Controlled, Double-Blind Study

par Fukase, Hiroyuki, Kajioka, Toshifumi, Oikawa, Ichiro, Ikeda, Naoki, Furuie, Hidetoshi
Publié dans Clin Drug Investig (2020)

AJM300, a novel oral antagonist of α4‐integrin, sustains an increase in circulating lymphocytes: A randomised controlled trial in healthy male subjects

par Fukase, Hiroyuki, Kajioka, Toshifumi, Oikawa, Ichiro, Ikeda, Naoki, Furuie, Hidetoshi
Publié dans Br J Clin Pharmacol (2020)

Relative and Absolute Bioavailability Study of Emicizumab to Bridge Drug Products and Subcutaneous Injection Sites in Healthy Volunteers

par Kotani, Naoki, Yoneyama, Koichiro, Kawakami, Nobuhiko, Shimuta, Tohru, Fukase, Hiroyuki, Kawanishi, Takehiko
Publié dans Clin Pharmacol Drug Dev (2018)

Effects of mild and moderate renal dysfunction on pharmacokinetics, pharmacodynamics, and safety of dotinurad: a novel selective urate reabsorption inhibitor

par Fukase, Hiroyuki, Okui, Daisuke, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo, Hosoya, Tatsuo
Publié dans Clin Exp Nephrol (2019)