Canlyniadau Chwilio - Frauke Swieringa

Combining human platelet proteomes and transcriptomes: possibilities and challenges gan Jingnan Huang, Johan W.M. Heemskerk, Frauke Swieringa

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Use of microfluidics to assess the platelet-based control of coagulation gan Magdolna Nagy, Johan W. M. Heemskerk, Frauke Swieringa

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Automated Imaging and Analysis of Platelet, Coagulation and Fibrinolysis Activities Using a Novel Flow Chip-Based System at Physiological Temperature gan Xiang Gui, Bibian M. E. Tullemans, Bas de Laat, Johan W. M. Heemskerk, Frauke Swieringa

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Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis gan Isabella Provenzale, Sanne L. N. Brouns, Paola E. J. van der Meijden, Frauke Swieringa, Johan W. M. Heemskerk

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Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow gan Frauke Swieringa, Marijke J. E. Kuijpers, Moniek M. E. Lamers, Paola E. J. van der Meijden, Johan W. M. Heemskerk

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Reversing direct factor Xa or thrombin inhibitors: Factor V addition to prothrombin complex concentrate is beneficial in vitro gan Herm Jan M. Brinkman, Frauke Swieringa, Marleen Zuurveld, Alicia Veninga, Sanne L. N. Brouns, Johan W. M. Heemskerk, Joost C. M. Meijers

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Platelet Activation Pathways Controlling Reversible Integrin αIIbβ3 Activation gan Jinmi Zou, Siyu Sun, Ilaria De Simone, Hugo ten Cate, Philip G. de Groot, Bas de Laat, Mark Roest, Johan W.M. Heemskerk, Frauke Swieringa

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Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions gan Jingnan Huang, Frauke Swieringa, Fiorella A. Solari, Isabella Provenzale, Luigi Grassi, Ilaria De Simone, Constance C. F. M. J. Baaten, Rachel Cavill, Albert Sickmann, Mattia Frontini, Johan W. M. Heemskerk

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Quantitative and qualitative changes in platelet traits of sunitinib-treated patients with renal cell carcinoma in relation to circulating sunitinib levels: a proof-of-concept stud... gan Bibian M. E. Tullemans, Sanne L. N. Brouns, Frauke Swieringa, Siamack Sabrkhany, Franchette W. P. J. van den Berkmortel, Natascha A. J. B. Peters, Peter de Bruijn, Stijn L. W. Koolen, Johan W. M. Heemskerk, Maureen J. B. Aarts, Marijke J. E. Kuijpers

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Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication gan Constance C. F. M. J. Baaten, Leo F. Veenstra, Rick Wetzels, Johanna P. van Geffen, Frauke Swieringa, Susanne M. de Witt, Yvonne M. C. Henskens, Harry Crijns, Sven Nylander, J. J. J. van Giezen, Johan W. M. Heemskerk, Paola E. J. van der Meijden

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Human and mouse platelet transcriptomes and proteomes for phenotyping 3474 genes with hemostatic and platelet traits gan Jingnan Huang, Federico Marini, Fiorella A. Solari, Frauke Swieringa, Bas de Laat, Ilaria De Simone, Luigi Grassi, Xiang Gui, Kunpeng Li, Elizabeth A. Middleton, Neil V. Morgan, Isabella Provenzale, Carina Santos, Saskia Schols, Sarah Westbury, Albert Sickmann, Matthew T. Rondina, Wolfram Ruf, Mattia Frontini, Johan W. M. Heemskerk

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Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome gan Johanna P. van Geffen, Frauke Swieringa, Kim van Kuijk, Bibian M. E. Tullemans, Fiorella A. Solari, Bing Peng, Kenneth J. Clemetson, Richard W. Farndale, Ludwig J. Dubois, Albert Sickmann, René P. Zahedi, Robert Ahrends, Erik A. L. Biessen, Judith C. Sluimer, Johan W. M. Heemskerk, Marijke J. E. Kuijpers

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Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy gan Constance C. F. M. J. Baaten, Floor C. J. I. Moenen, Yvonne M. C. Henskens, Frauke Swieringa, Rick J. H. Wetzels, René van Oerle, Harry F. G. Heijnen, Hugo ten Cate, Graham P. Holloway, Erik A. M. Beckers, Johan W. M. Heemskerk, Paola E. J. van der Meijden

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High-throughput elucidation of thrombus formation reveals sources of platelet function variability gan Johanna P. van Geffen, Sanne L.N. Brouns, Joana Batista, Harriet McKinney, Carly Kempster, Magdolna Nagy, Suthesh Sivapalaratnam, Constance C.F.M.J. Baaten, Nikki Bourry, Mattia Frontini, Kerstin Jurk, Manuela Krause, Daniele Pillitteri, Frauke Swieringa, Remco Verdoold, Rachel Cavill, Marijke J. E. Kuijpers, Willem H. Ouwehand, Kate Downes, Johan W.M. Heemskerk

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Case Report: Laboratory detection of a thrombotic tendency in a family with hypodysfibrinogenemia and a novel FGG mutation gan Amaury Monard, Amaury Monard, Elisabetta Castoldi, Ilaria De Simone, Kanin Wichapong, Tirsa van Duijl, Maartje van den Biggelaar, Stefano Spada, Stefano Spada, William van Doorn, Dave Hellenbrand, Paola van der Meijden, Paola van der Meijden, Frauke Swieringa, Alexander Stork, Hugo ten Cate, Hugo ten Cate, Erik Beckers, Floor Heubel-Moenen, Yvonne Henskens, Yvonne Henskens

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Coated platelets function in platelet-dependent fibrin formation via integrin αIIbβ3 and transglutaminase factor XIII gan Nadine J.A. Mattheij, Frauke Swieringa, Tom G. Mastenbroek, Michelle A. Berny-Lang, Frauke May, Constance C.F.M.J. Baaten, Paola E.J. van der Meijden, Yvonne M.C. Henskens, Erik A.M. Beckers, Dennis P.L. Suylen, Marc W. Nolte, Tilman M. Hackeng, Owen J.T. McCarty, Johan W.M. Heemskerk, Judith M.E.M. Cosemans

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