The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity

by Francesca Di Cristo, Anna Calarco, Filomena Anna Digilio, Maria Stefania Sinicropi, Camillo Rosano, Umberto Galderisi, Mariarosa Anna Beatrice Melone, Carmela Saturnino, Gianfranco Peluso
Published 2020-10-01

Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies...

by Claudia Riccardi, Federica D’Aria, Filomena Anna Digilio, Maria Rosaria Carillo, Jussara Amato, Dominga Fasano, Laura De Rosa, Simona Paladino, Mariarosa Anna Beatrice Melone, Daniela Montesarchio, Concetta Giancola
Published 2022-04-01